Pleomorphic Xanthoastrocytoma

Rao, G. Mallikarjuna; Kestle, John R. W.

doi:10.1016/b978-0-7216-8148-1.50089-9

Cited by 1 publication

(2 citation statements)

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“…Postoperative radiotherapy is reserved for patients with anaplastic and recurrent tumors with malignant changes (4, 5, 22, 33). Chemotherapy has not been adequately studied (30).…”

Section: A B C Dmentioning

confidence: 99%

“…Examples of this unusual neoplasm have also been reported in the cerebellum (11,12,14,23,31,35), pineal region (27), sella turcica (2), spinal cord (15,26), and even the retina (40). PXA often arises in adolescents and young adults and is amenable to surgical resection with good disease control (8), although it may harbor the potential for malignant transformation (1, 4, 5,6,9,25,28,30,32,38). To our knowledge, this is the first reported case of a solid PXA located exclusively within the third ventricle, a site not previously described in the literature.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Intraventricular pleomorphic xanthoastrocytoma: a case report

Menéndez¹,

Fernández²,

MonTI³

et al. 2014

Turkish Neurosurgery

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Pleomorphic xanthoastrocytoma (PXA), an uncommon glial neoplasm, typically affects adolescents and young adults and accounts for less than 1% of all astrocytic neoplasms. The authors present a case of PXA located entirely in the third ventricle in a 24-year-old male patient. The patient presented with a 6-month history of headaches, progressive decline in cognitive function and profound behavioral disturbances. He was admitted to the hospital with signs of increased intracranial pressure. Magnetic resonance imaging showed a well-enhanced solid tumor, located entirely inside the third ventricle. The tumor was totally removed via a right fronto-pterional trans-lamina terminalis approach and neuropathology report confirmed PXA diagnosis. No further treatment was indicated. To the best of our knowledge, this is the first case report of a solid PXA confined to the third ventricle. KEywoRds: Pleomorphic xanthoastrocytoma, Intraventricular, Immuno-histochemical ÖZPleomorfik ksantoastrositom (PXA) nadir bir gliyal neoplazidir ve tipik olarak adolesanlar ve genç yetişkinlerde görülüp, tüm astrositik neoplazmların %1'inden azını oluşturur. Yazarlar 24 yaşında bir erkek hastada tamamen üçüncü ventrikülde bulunan PXA olgusu sunmaktadır. Hasta 6 aylık başağrısı, bilişsel işlevde giderek azalma ve belirgin davranış bozuklukları öyküsüyle geldi. Artmış intrakraniyal basınç bulgularıyla hastaneye yatırıldı. Manyetik rezonans görüntüleme tamamen üçüncü ventrikül içinde bulunan ve iyi kontrast tutan bir solid tümör gösterdi. Tümör sağ fronto-pterional trans-lamina terminalis yaklaşımı ile tamamen çıkarıldı ve nöropatoloji raporu PXA tanısını doğruladı. Başka bir tedavi gerekmedi. Bildiğimiz kadarıyla bu üçüncü ventrikülle sınırlı solid bir PXA için ilk olgu raporudur.

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“…Postoperative radiotherapy is reserved for patients with anaplastic and recurrent tumors with malignant changes (4, 5, 22, 33). Chemotherapy has not been adequately studied (30).…”

Section: A B C Dmentioning

confidence: 99%