Pleural Effusion As The Initial Extramedullary Manifestation Of AML

Boodoosingh, Dev R.; Hernández, Luis Ruiz; Fernández, Ricardo; Fernández, Francisco Ruiz; Velez, Felipe; Torrellas, Pedro; Olmo, Francisco Del; Sanchez, Alfredo; Fernández, Ricardo Antonio Menéndez; Adorno, Jose

doi:10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a5901

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“…Pleural fluid yielded exudative criteria with 62% leukaemic myeloblasts. Confirmation was done by BM biopsy [7]. Unilateral pleural effusion associated with AML has been reported by Fatih et al [3], Nieves-Nieves et al [8], and Ohe et al [9].…”

Section: Discussionmentioning

confidence: 99%

ecancermedicalscience

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Haematologic malignancies such as acute and chronic leukaemias rarely present with or develop pleural effusion during their clinical course. We present a case of a young female who presented with unilateral pleural effusion and was diagnosed with haematologic malignancy on pleural fluid cytology. On further workup, a diagnosis of acute myeloid leukaemia was established. The patient was put on chemotherapy thereafter. This case clearly highlights the importance of cytopathology aids in making a diagnosis of rare and unusual presentation in haematologic malignancies.

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Section: Discussionmentioning

confidence: 99%