Plexiform (multinodular) schwannoma

Woodruff, James M.; Marshall, Mary L.; Godwin, Thomas; Funkhouser, James W.; Thompson, Nicholas J.; Erlandson, Robert A.

doi:10.1097/00000478-198310000-00009

Cited by 103 publications

(11 citation statements)

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“…These features made us suspect that the tumor was a Schwannoma. However, it is well known that Schwannoma-like lesions can be seen in some neurofibromas [4,5]. However in our case, there was absolutely no sign of axon differentiation in the tumor, and we observed no neurofilament-positive areas.…”

Section: Introductioncontrasting

confidence: 56%

“…Manual muscle testing of his left upper extremity revealed the following results: deltoid [1], biceps [1], brachioradialis [0], triceps [4], extensor digitorum [2], extensor digiti minimi [2], extensor pollicis brevis [2], extensor pollicis longus [2], extensor indicis [2], extensor carpi radialis [4], extensor carpi ulnaris [4], flexor carpi radialis [0], flexor carpi ulnaris [5], pronator teres [0], pronator quadratus [0], flexor digitorum superficiali [I-IV][0], flexor digitorum profindus (index finger) [0] and II-IV [5], flexor pollicis longus [0], flexor pollicis brevis [0], and flexor digiti minimi [0]. There was sensory loss in his axillary nerve, lateral brachial cutaneous nerve, and median nerve.…”

Section: Introductionmentioning

confidence: 99%

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A giant plexiform schwannoma of the brachial plexus: case report

Kohyama

Hara

Nishiura

et al. 2014

J Brachial Plex Peripher Nerve Inj

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We report the case of a patient who noticed muscle weakness in his left arm 5 years earlier. On examination, a biloculate mass was observed in the left supraclavicular area, and Tinel's sign caused paresthesia in his left arm. Magnetic resonance imaging showed a continuous, multinodular, plexiform tumor from the left C5 to C7 nerve root along the course of the brachial plexus to the left brachia. Tumor excision was attempted. The median and musculocutaneous nerves were extremely enlarged by the tumor, which was approximately 40 cm in length, and showed no response to electric stimulation. We resected a part of the musculocutaneous nerve for biopsy and performed latissimus dorsi muscle transposition in order to repair elbow flexion. Morphologically, the tumor consisted of typical Antoni A areas, and immunohistochemistry revealed a Schwann cell origin of the tumor cells moreover, there was no sign of axon differentiation in the tumor. Therefore, the final diagnosis of plexiform Schwannoma was confirmed.

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Section: Introductioncontrasting

confidence: 56%

Section: Introductionmentioning

confidence: 99%

A giant plexiform schwannoma of the brachial plexus: case report

Kohyama

Hara

Nishiura

et al. 2014

J Brachial Plex Peripher Nerve Inj

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“…The only report vulvar neurilemmoma recurred, beside our case, was a patient with the plexiform type who recurred twice, and was alive and well three years after the second resection [9].…”

Section: Discussionmentioning

confidence: 54%

“…There was five cases reported of plexiform variants despite is one of the least common histologic variants [9] [13] [15].…”

Section: Discussionmentioning

confidence: 99%

Schwanoma Vulvar

Gutiérrez¹,

Campo²,

García³

et al. 2017

OALib

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Schwannoma, also known as neurinoma or neurilemmoma, is a benign tumor that arises from the Schwann cells of the nerve sheath. This neoplasm often affects peripheral nerves although it may occur in soft tissues. Vulval location is extremely rare. We relate the case report of a 45-year-old woman with history of vulval mass excised in 2012 and diagnosed as benign schwannoma. She currently presents with local recurrence.

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“…Despite considered painless, penile schwannomas have been associated with painful intercourse, erectile dysfunction, and penile curvature[2]. Differential diagnosis includes Peyronie's disease, fibrosis after intracavernosal injections, lipomas, leiomyomas, sarcomas, and the other schwannoma subtypes [9]. Histopathology is the only safe means to distinguish them from other benign lesions [10, 11].…”

Section: Discussionmentioning

confidence: 99%

Plexiform Schwannoma of the Penis: A Rare Subtype of Genital Schwannoma

Gkekas

Kalyvas

Symeonidis

et al. 2019

Case Reports in Urology

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Schwannomas are benign, encapsulated neurogenic tumors which present in diverse histological subtypes despite the limited variety of their cellular constituents. These include the cellular, ancient, cystic, epithelioid, melanotic, psammomatous, schwannoma with pseudoglandular elements, and plexiform varieties. The plexiform schwannoma (PS) represents 4.3% of all schwannomas. These lesions are commonly encountered in the head and neck region and are extremely rare in the penis. To the best of our knowledge only 34 cases of penile schwannomas have been reported and this is the 3rd case of plexiform penile schwannoma. A 39-year-old patient presented to our andrology outpatient clinic complaining for two painful penile nodules. The lesions were located on the dorsum of the penile shaft. His medical history was insignificant for penile trauma and sexual transmitted diseases. The masses measured 2x1 cm and 0.5x1 cm. After sonographic and magnetic resonance evaluation the patient was admitted to theatre and underwent topical resection of the lesions. Histopathology revealed plexiform schwannoma. Postoperatively, penile tenderness and hyperesthesia ensued which was managed with pregabalin administration and topical corticosteroids. Plexiform schwannomas are rare in the penile region. Surgical excision is inevitably the only way to diagnose and treat the lesions. They must be differentiated by a variety of malignant and benign clinical conditions. Topical excision suffices for oncological control and allows for acceptable functional outcomes.

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Plexiform (multinodular) schwannoma

Cited by 103 publications

References 0 publications

A giant plexiform schwannoma of the brachial plexus: case report

A giant plexiform schwannoma of the brachial plexus: case report

Schwanoma Vulvar

Plexiform Schwannoma of the Penis: A Rare Subtype of Genital Schwannoma

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