Plexin B3 guides axons to cross the midline in vivo
Zhi-Zhi Liu,
Ling-Yan Liu,
Lou-Yin Zhu
et al.
Abstract:During the development of neural circuits, axons are guided by a variety of molecular cues to navigate through the brain and establish precise connections with correct partners at the right time and place. Many axon guidance cues have been identified and they play pleiotropic roles in not only axon guidance but also axon fasciculation, axon pruning, and synaptogenesis as well as cell migration, angiogenesis, and bone formation. In search of receptors for Sema3E in axon guidance, we unexpectedly found that Plex… Show more
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