Plug-in optical fiber SPR biosensor for lung cancer gene detection with temperature and pH compensation

Li, Xuegang; Gong, Pengqi; Zhao, Qi; Zhou, Xue; Zhang, Yanan; Zhao, Yong

doi:10.1016/j.snb.2022.131596

Cited by 70 publications

(15 citation statements)

References 30 publications

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“…During the past five years, the above-mentioned new structure has been widely used in actual detection, involving different biomolecules [ 12 ], chemicals [ 13 ], and temperature [ 14 ]. This detection function can be used in a wide range of applications such as the water environment pH value and RI [ 15 ], various gases [ 16 ], and humidity [ 17 ].…”

Section: Special Optical Fiber Structure-based Biosensing Applicationsmentioning

confidence: 99%

“…For this, the perception of external subtle changes is then realized through data demodulation and processing. According to these steps, it can be applied to detect different biomolecules [ 12 ], chemicals [ 13 ], and temperature [ 14 ], and also a wide range of other applications such as the water environment pH value and RI [ 15 ], various gases [ 16 ], humidity [ 17 ] etc. However, with the increasing demand for the application of sensor technology, especially in life science, clinical diagnosis, medicine, and food safety, the sensitivity and specificity of plasma sensors for low-dose analyte detection are required to be higher [ 18 ].…”

Section: Introductionmentioning

confidence: 99%

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Novel Optical Fiber-Based Structures for Plasmonics Sensors

et al. 2022

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Optical fiber sensors based on surface plasma technology have many unique advantages in specific applications such as extreme environmental monitoring, physical parameter determination, and biomedical indicators testing. In recent decades, various kinds of fiber probes with special structures were developed according to special processing such as tapering, splicing, etching, fiber balls, grating etc. In this paper, the fabrication technology, characteristics, development status and application scenarios of different special optical fiber structures are briefly reviewed, including common processing equipment. Furthermore, many special novel optical fiber structures reported in recent years are summarized, which have been used in various kinds of plasmonic sensing work. Then, the fiber-plasmonic sensors for practical applications are also introduced and examined in detail. The main aim of this review is to provide guidance and inspiration for researchers to design and fabricate special optical fiber structures, thus facilitating their further research.

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Section: Special Optical Fiber Structure-based Biosensing Applicationsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Novel Optical Fiber-Based Structures for Plasmonics Sensors

et al. 2022

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“…In addition, Teng et al [ 21 ] obtained temperature-compensated refractive index measurements with a sensitivity of up to 1258 nm/RIU by vaporizing Au films on both polished sides of a U-shape plastic fiber and then coating one of the Au film surfaces with PDMS. Lia et al [ 22 ] coated PDNA and PH-sensitive material PAA/CS on the surface of FBG, eliminated the influence of ambient temperature and ph value and realized DNA sequence detection. To excite temperature-sensitive SPR channels, Wei et al [ 23 ] used a graded-index multi-mode fiber (GI-MMF) as the displacement sensing region (DSR) and hetero-core fiber as the temperature sensing region (TSR) coated with polydimethylsiloxane (PDMS) temperature-sensitive material.…”

Section: Introductionmentioning

confidence: 99%

Research Advances on Fiber-Optic SPR Sensors with Temperature Self-Compensation

Zhao

Wang

Han

et al. 2023

Sensors

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The fiber-optic surface plasmon resonance sensor has very promising applications in environmental monitoring, biochemical sensing, and medical diagnosis, due to the superiority of high sensitivity and novel label-free microstructure. However, the influence of ambient temperature is inevitable in practical sensing applications, and even the higher the sensitivity, the greater the influence. Therefore, how to eliminate temperature interference in the sensing process has become one of the hot issues of this research field in recent years, and some accomplishments have been achieved. This paper mainly reviews the research results on temperature self-compensating fiber-optic surface plasmon sensors. Firstly, it introduces the mechanism of a temperature self-compensating fiber-optic surface plasmon resonance sensor. Then, the latest development of temperature self-compensated sensor is reviewed from the perspective of various fiber-optic sensing structures. Finally, this paper discusses the most recent applications and development prospects of temperature self-compensated fiber-optic surface plasmon resonance sensors.

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“…In terms of price, size, and convenience of in situ label-free technique development, the use of fiber optic devices as biological/chemical sensing components provides numerous important benefits over electrochemical approaches. As a result, fiber-based biosensors have gained popularity and provide a novel approach for the wide range detection of biological analytes [ 5 , 6 , 7 , 8 ]. Many geometrically modified and microstructured fibers, including side-polished fibers [ 9 , 10 ], D-shaped fibers [ 11 , 12 , 13 , 14 ], U-shaped fibers [ 15 ], tapered fibers [ 16 , 17 , 18 , 19 ], microsphere structured fibers [ 20 , 21 ], photonic crystal fibers (PCF) [ 22 , 23 , 24 , 25 ], and grating fibers [ 26 , 27 , 28 , 29 , 30 ], are employed to draw the guiding mode out of the cladding to interact with the surrounding environment.…”

Section: Introductionmentioning

confidence: 99%

“…Two-dimensional metal films and three-dimensional (3D) nanoarrays play an important role in enhancing the local electric field of optical fiber structures so they can be used in the development of SPR-based optical fiber biosensors. These sensing systems can detect a large number of molecules of clinical relevance, including glucose [ 56 , 57 ], bacteria [ 58 , 59 ], cancer cells [ 6 , 60 ], dopamine [ 61 , 62 , 63 ], deoxyribonucleic acid (DNA) [ 41 ], and so on. The applications of different types of nanomaterials based on different sensing principles are represented in Figure 1 .…”

Section: Introductionmentioning

confidence: 99%

Advances in Novel Nanomaterial-Based Optical Fiber Biosensors—A Review

Singh

Wang

et al. 2022

Biosensors

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This article presents a concise summary of current advancements in novel nanomaterial-based optical fiber biosensors. The beneficial optical and biological properties of nanomaterials, such as nanoparticle size-dependent signal amplification, plasmon resonance, and charge-transfer capabilities, are widely used in biosensing applications. Due to the biocompatibility and bioreceptor combination, the nanomaterials enhance the sensitivity, limit of detection, specificity, and response time of sensing probes, as well as the signal-to-noise ratio of fiber optic biosensing platforms. This has established a practical method for improving the performance of fiber optic biosensors. With the aforementioned outstanding nanomaterial properties, the development of fiber optic biosensors has been efficiently promoted. This paper reviews the application of numerous novel nanomaterials in the field of optical fiber biosensing and provides a brief explanation of the fiber sensing mechanism.

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Plug-in optical fiber SPR biosensor for lung cancer gene detection with temperature and pH compensation

Cited by 70 publications

References 30 publications

Novel Optical Fiber-Based Structures for Plasmonics Sensors

Novel Optical Fiber-Based Structures for Plasmonics Sensors

Research Advances on Fiber-Optic SPR Sensors with Temperature Self-Compensation

Advances in Novel Nanomaterial-Based Optical Fiber Biosensors—A Review

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