Abstract:IntroductionLiquid biopsies provide a non-invasive method to acquire the genetic information provided in cell-free DNA (cfDNA) as well as in single circulating tumour cells. Access to this genetic information through next-generation sequencing (NGS) identifies mutations and alterations such as Copy Number Variation (CNV) that play a role in cancer and other diseases.Material and methodsThe key to identifying rare mutations is improved sequencing accuracy and the ability to distinguish between biological and PC… Show more
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