Policy Considerations Regarding Genome Editing

Friedrichs, Steffi; Takasu, Yoko; Kearns, Peter; Dagallier, Bertrand; Oshima, Ryudai; Schofield, Janet Ward; Moreddu, Catherine

doi:10.1016/j.tibtech.2019.05.005

Cited by 30 publications

(16 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The Organization for Economic Co-operation and Development (OECD) recognizes increasing impact of emerging new breeding technologies such as genome editing on global economies. For that reason, the OECD Conference on Genome Editing: Applications in Agriculture was held in June 2018 bringing together relevant stakeholders like scientific experts, decision makers, company representatives and others from more than 35 countries ( OECD Review of Fisheries: Policies and Summary Statistics 2017 , OECD, 2017 ; Friedrichs et al, 2019 ). Participants discussed that regulatory approaches for genome editing should be determined to achieve policy objectives considering both, precaution and innovation through better communication between all stakeholders ( Friedrichs et al, 2019 ).…”

Section: Developments In Global Organizationsmentioning

confidence: 99%

See 1 more Smart Citation

Genome Edited Crops Touch the Market: A View on the Global Development and Regulatory Environment

et al. 2020

View full text Add to dashboard Cite

Products of genome editing as the most promising “New Plant Breeding Technology” (NPBT) have made the transition from the lab to the market in a short time. Globally, research activities employing genome editing are constantly expanding and more and more plants with market-oriented traits are being developed, and companies have already released the first genome edited crops to the market. Few countries, most of which are located in the Americas, have adapted legislations to these technologies or released guidelines supporting the use of genome editing. Other countries are debating the path to come either because there is no clarity on the legal classification or due consensus is hampered by a renewed GMO debate. In recent years (2017−2020), eight countries have introduced guidelines clarifying the legal status of genome edited products and many of those are actively committed to international harmonization of their policies. In this publication we give an overview on the current and potentially future international regulatory environment and an update on plants derived by genome editing with market-oriented traits.

show abstract

Section: Developments In Global Organizationsmentioning

confidence: 99%

“…Furthermore, it is important that the different legal systems understand their respective regulatory and policy approaches to genome editing. To minimize difficulties arising through different regulatory approaches a common understanding is obligatory ( Friedrichs et al, 2019 ).…”

Section: Developments In Global Organizationsmentioning

confidence: 99%

Genome Edited Crops Touch the Market: A View on the Global Development and Regulatory Environment

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Some of these questions are currently a matter of lively discussions in the synthetic biology arena, such as the role of evolution in the performance of synthetic organisms or how (and if) a bioprocess based on such organisms could be scaled up [11]. These emerging approaches will also shine a new light on safety assessment and regulation of genome-edited products [12], since the properties of whole-cell catalysts (including those that should be avoided) will be rendered amenable to tailoring. One way or the other, the work by Fredens and colleagues constitutes a formidable stepping stone toward the understanding and (re)programming of the core properties of the cellthe consequences of which will start to become evident in the near future, particularly in the domain of bioproduction.…”

Section: Synthesis Of Recoded Bacterial Genomes Toward Bespoke Biocatmentioning

confidence: 99%

Synthesis of Recoded Bacterial Genomes toward Bespoke Biocatalysis

Nikel

2019

Trends in Biotechnology

View full text Add to dashboard Cite

 Users may download and print one copy of any publication from the public portal for the purpose of private study or research.  You may not further distribute the material or use it for any profit-making activity or commercial gain  You may freely distribute the URL identifying the publication in the public portal If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim.

show abstract

“…Proponents consider the procedures to be faster, more precise, more effective, and thus significantly less expensive than classical genetic engineering techniques, and the hope has been expressed that this might make them more accessible for use by small and medium-sized enterprises. At the same time, NBTs have given rise to a number of concerns, e.g., regarding risks associated with side effects and off-target effects, as well as the possibility of negative socio-economic impacts, and there is an ongoing debate about responsible regulation [17][18][19][20][21][22]. Possible conflicts of interest in research and regulation are also an issue, for example, when research is publicly funded [23,24].…”

Section: Introductionmentioning

confidence: 99%

“…Fourteen EU member states have called for a "unified approach" on the EU level [28] that could lead to a more liberal approach, exempting some NBTs from GMO regulation. Also unclear is how the ruling could be applied to imported goods, as NBTs are already in use in some countries, such as the USA, where some products and product groups produced using NBTs cannot be distinguished using currently available technologies from those of conventional agriculture [21]. On 8 November 2019, the European Commission was requested by the EU member states to study "the status of novel genomic techniques under Union law" [29].…”

Section: Introductionmentioning

confidence: 99%

Pathways of Conflict: Lessons from the Cultivation of MON810 in Germany in 2005–2008 for Emerging Conflicts over New Breeding Techniques

Friedrich

2019

Sustainability

View full text Add to dashboard Cite

The paper uses qualitative interviews and document analysis to examine conflicts over plant and animal breeding techniques from the perspectives of Social and Political Ecology. It asks how past conflicts over genetically modified organisms (GMOs) can inform understandings of possible trajectories of emerging conflicts over new breeding techniques (NBTs) such as CRISPR/Cas genome editing. Case studies of conflicts in three areas where the transgenic maize MON810 was cultivated in Germany from 2005–2008 show that the escalation of conflict coincided with the first tangible presence of these already controversial organisms in the rural landscape. Location-specific interlinkages between discursive and material dimensions gave rise to different pathways of conflict in the three areas studied. These empirical results inform the analysis of emerging conflicts over NBTs in Germany and the United Kingdom. The future of NBTs in both countries is still open, and the divergence of regulatory frameworks in Europe could lead to the development of ‘NBT hotspots’ located in particular European countries, provoking an escalation of conflict in areas where commercial application takes place. The paper concludes by examining the potential for a politicization of future conflicts to encompass wider issues related to the transformation of agricultural systems towards sustainability.

show abstract

Policy Considerations Regarding Genome Editing

Cited by 30 publications

References 2 publications

Genome Edited Crops Touch the Market: A View on the Global Development and Regulatory Environment

Genome Edited Crops Touch the Market: A View on the Global Development and Regulatory Environment

Synthesis of Recoded Bacterial Genomes toward Bespoke Biocatalysis

Pathways of Conflict: Lessons from the Cultivation of MON810 in Germany in 2005–2008 for Emerging Conflicts over New Breeding Techniques

Contact Info

Product

Resources

About