Poly (vinyl alcohol) (PVA) hydrogel incorporated with Ag/TiO2 for rapid sterilization by photoinspired radical oxygen species and promotion of wound healing

Wang, Jiameng; Zhang, Chao; Yang, Yongqiang; Fan, Ailan; Chi, Rui‐Fang; Shi, Jing; Zhang, Xiangyu

doi:10.1016/j.apsusc.2019.07.224

Cited by 63 publications

(59 citation statements)

References 34 publications

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“…[ 204 ] Zhang's research showed that embedding Ag‐doped TiO 2 into PVA hydrogels via freeze‐thaw cycles five times effectively enhanced the antibacterial activities of hybrid hydrogel against E. coli and S. aureus under the irradiation of 660 nm visible light for 5 min. [ 205 ]…”

Section: Light‐mediated Antibacterial Hydrogelsmentioning

confidence: 99%

Antibacterial Hybrid Hydrogels

Cao

Luo

et al. 2020

Macromolecular Bioscience

136

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Bacterial infectious diseases and bacterial‐infected environments have been threatening the health of human beings all over the world. In view of the increased bacteria resistance caused by overuse or improper use of antibiotics, antibacterial biomaterials are developed as the substitutes for antibiotics in some cases. Among them, antibacterial hydrogels are attracting more and more attention due to easy preparation process and diversity of structures by changing their chemical cross‐linkers via covalent bonds or noncovalent physical interactions, which can endow them with various specific functions such as high toughness and stretchability, injectability, self‐healing, tissue adhesiveness and rapid hemostasis, easy loading and controlled drug release, superior biocompatibility and antioxidation as well as good conductivity. In this review, the recent progress of antibacterial hydrogel including the fabrication methodologies, interior structures, performances, antibacterial mechanisms, and applications of various antibacterial hydrogels is summarized. According to the bacteria‐killing modes of hydrogels, several representative hydrogels such as silver nanoparticles‐based hydrogel, photoresponsive hydrogel including photothermal and photocatalytic, self‐bacteria‐killing hydrogel such as inherent antibacterial peptides and cationic polymers, and antibiotics‐loading hydrogel are focused on. Furthermore, current challenges of antibacterial hydrogels are discussed and future perspectives in this field are also proposed.

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Section: Light‐mediated Antibacterial Hydrogelsmentioning

confidence: 99%

Antibacterial Hybrid Hydrogels

Cao

Luo

et al. 2020

Macromolecular Bioscience

136

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“…Briefly, after Ag/TiO 2 irradiation with visible light, a charge transfer to Ag nanoparticles suppresses the electron–hole recombination, and reactive oxygen species can be formed by transfer to molecular oxygen or by water’s loss of a proton to form hydroxyl radicals. Using this elegant platform design, the photocatalytic activity of TiO 2 was extended to the visible region, while the toxicity of silver nanoparticles was reduced due to hydrogel entrapment [ 83 ].…”

Section: Photosensitizing Dyesmentioning

confidence: 99%

“…Hydrogels based on poly(vinyl alcohol) (PVA) containing Ag-doped TiO 2 nanoparticles were prepared using a simple two-step process ( Figure 28 A) [ 83 ]. The procedure involved the addition of the desired amount of AgNO 3 to TiO 2 nanoparticles dispersed in deionized water with sodium dodecylbenzenesulfonate (SDBS), followed by the chemical reduction of Ag + in the presence of glucose.…”

Section: Photosensitizing Dyesmentioning

confidence: 99%

“… Influence of Ag/TiO 2 nanoparticle hydrogel on mouse infected wound healing. ( A ) Ag/TiO 2 nanoparticle hydrogel preparation and ROS production under red light irradiation at 660 nm; ( B ) photographs of wound regions of control, 3 M, TiO 2 HD and 0.5% HD groups under light irradiation at 660 nm; ( C ) Percentage of wound area over 14 days of treatment) (figure adapted from [ 83 ] with permission of Elsevier). …”

Section: Figurementioning

confidence: 99%

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An Insight into the Role of Non-Porphyrinoid Photosensitizers for Skin Wound Healing

Vallejo

Moura

Faustino

et al. 2020

IJMS

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The concept behind photodynamic therapy (PDT) is being successfully applied in different biomedical contexts such as cancer diseases, inactivation of microorganisms and, more recently, to improve wound healing and tissue regeneration. The effectiveness of PDT in skin treatments is associated with the role of reactive oxygen species (ROS) produced by a photosensitizer (PS), which acts as a “double agent”. The release of ROS must be high enough to prevent microbial growth and, simultaneously, to accelerate the immune system response by recruiting important regenerative agents to the wound site. The growing interest in this subject is reflected by the increasing number of studies concerning the optimization of relevant experimental parameters for wound healing via PDT, namely, light features, the structure and concentration of the PS, and the wound type and location. Considering the importance of developing PSs with suitable features for this emergent topic concerning skin wound healing, in this review, a special focus on the achievements attained for each PS class, namely, of the non-porphyrinoid type, is given.

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“…TiO 2 nanorods and CdS particles were uniformly distributed in the composite, and the optical response range was extended to the visible light region.Catalysts 2020, 10, 441 2 of 14 coating, the nitric oxide (NO x ) in the atmosphere [8,9], sulfur oxide [10,11] and other pollutants such as halogenated hydrocarbons [12,13], aldehydes [14], and polycyclic aromatic hydrocarbons from automotive exhaust gas can be absorbed and degraded [15,16]. TiO 2 also shows a good performance in light-sensitive solar cells [17] and biomedical devices [18]. In addition, nano-TiO 2 has broad applications in many aspects such as sterilization, degradation, deodorization, self-cleaning and energy storage [19][20][21][22][23].…”

mentioning

confidence: 99%

Preparation of CdS Nanoparticles-TiO2 Nanorod Hererojunction and Their High-Performance Photocatalytic Activity

et al. 2020

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As a new and emerging technology, photocatalytic oxidation is widely used in the fields of sewage treatment and organic pollution control. In this study, CdS nanoparticles were prepared at room temperature by an innovative preparation method, then TiO2 nanorod–CdS nanoparticle heterojunction photocatalysts were prepared using the solvothermal method, with TiCl3 used as the precursor for TiO2 nanorods. This study mainly took advantage of the small size of the CdS nanoparticles in combination with TiO2 nanorods, and the resultant heterojunctions had large specific surface areas, thereby increasing the contact area between the catalysts and the contaminants. In addition, due to the lower band gap energy (2.4 eV) of CdS, the photo response range of the heterojunction photocatalysts was also increased. In an experimental study, through photocatalytic performance tests of the catalysts with different weight ratios, it was found that the TiO2(40%)@CdS composite had the best photocatalytic performance and the highest catalytic rate. BET, SEM, and other tests showed that the specific surface area of the TiO2(40%)@CdS composite was the largest. TiO2 nanorods and CdS particles were uniformly distributed in the composite, and the optical response range was extended to the visible light region.

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Poly (vinyl alcohol) (PVA) hydrogel incorporated with Ag/TiO2 for rapid sterilization by photoinspired radical oxygen species and promotion of wound healing

Cited by 63 publications

References 34 publications

Antibacterial Hybrid Hydrogels

Antibacterial Hybrid Hydrogels

An Insight into the Role of Non-Porphyrinoid Photosensitizers for Skin Wound Healing

Preparation of CdS Nanoparticles-TiO2 Nanorod Hererojunction and Their High-Performance Photocatalytic Activity

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