Polycyclic aromatic hydrocarbons (PAHs): Updated aspects of their determination, kinetics in the human body, and toxicity

Barbosa, Fernando; Rocha, Bruno Alves; Souza, Marília Cristina Oliveira; Bocato, Mariana Zuccherato; Azevedo, Lcp; Adeyemi, Joseph A.; Santana, Anthony; Campiglia, Andrés D.

doi:10.1080/10937404.2022.2164390

Cited by 77 publications

(12 citation statements)

References 261 publications

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“…PHE is a typical light PAH consisting of three benzene rings. The United States Environmental Protection Agency (U.S. EPA) and the European Union have listed it as one of the 16 priority PAH pollutants, , so it is urgently required to develop efficient PHE removal technology. Due to the high specific surface area, good chemical stability, and abundant aromatic nuclei as adsorption sites, both DhaTAT and DhaTAB showed great promise in PHE adsorption and removal.…”

Section: Adsorption To Polycyclic Aromatic Hydrocarbonsmentioning

confidence: 99%

A Key to Crystallinity and Reusability of Covalent Organic Frameworks: Adsorption-Induced Deformation

Jin,

Li,

Zhou

et al. 2024

ACS Materials Lett.

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The design and synthesis of covalent organic frameworks (COFs) with excellent reusability are promising ways to advance practical applications in many fields, including as absorbents for environmental remediation. However, a lack of guiding principles makes it challenging. Herein, two COFs (DhaTAT and DhaTAB) are prepared and demonstrated to work excellently for the adsorption and removal of the representative environmental pollutant phenanthrene (PHE) with the highest adsorption capacity and the fastest adsorption kinetics reported so far. Although having comparable PHE adsorption performances, DhaTAT displays much better reusability than DhaTAB. By deeply exploring the underlying mechanism, we reveal for the first time the adverse effects of adsorption-induced deformation phenomenon on the crystallinity, morphology, specific surface area, and thus reusability of COFs, and propose that introducing electron-withdrawing groups can alleviate this phenomenon and endow COF-based adsorbents with excellent reusability. Such a prediction is further confirmed by the recycling performances of two new COFs (DapTFB and DanTFB) that are designed under the guidance of theoretical calculations. This study provides valuable insights into the effects of adsorption-induced deformation on the practical application potential of COFs, which is crucial for the development of new materials with stable adsorption performance and good reusability.

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Section: Adsorption To Polycyclic Aromatic Hydrocarbonsmentioning

confidence: 99%

A Key to Crystallinity and Reusability of Covalent Organic Frameworks: Adsorption-Induced Deformation

Jin,

Li,

Zhou

et al. 2024

ACS Materials Lett.

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“…87 PAHs, on the other hand, are a group of chemical compounds produced during incomplete combustion of organic materials, including coal, gasoline and tobacco smoke. 88 Numerous studies have demonstrated a link between exposure to PM2.5 and PAHs and an increased risk of endometriosis. 3,4,89,90 The presence of PM2.5 and PAHs in the pelvic cavity can lead to chronic inflammation, oxidative stress and DNA damage, all of which contribute to the development and progression of endometriotic lesions.…”

Section: A Ir Pol Lu Tion a N D E N Dom Etr Iosismentioning

confidence: 99%

“…These particles can originate from sources such as vehicle emissions, industrial processes and the burning of fossil fuels 87 . PAHs, on the other hand, are a group of chemical compounds produced during incomplete combustion of organic materials, including coal, gasoline and tobacco smoke 88 …”

Section: Air Pollution and Endometriosismentioning

confidence: 99%

Pollution and endometriosis: A deep dive into the environmental impacts on women's health

Vallée,

Ceccaldi,

Carbonnel

et al. 2023

BJOG

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BackgroundThe interaction between pollution and endometriosis is a pressing issue that demands immediate attention. The impact of pollution, particularly air and water pollution, or occupational hazards, on hormonal disruption and the initiation of endometriosis remains a major issue.ObjectivesThis narrative review aims to delve into the intricate connection between pollution and endometriosis, shedding light on how environmental factors contribute to the onset and severity of this disease and, thus, the possible public health policy implications.DiscussionEndocrine‐disrupting chemicals (EDCs) in pollutants dysregulate the hormonal balance, contributing to the progression of this major gynaecological disorder. Air pollution, specifically PM2.5 and PAHs, has been associated with an increased risk of endometriosis by enhancing chronic inflammation, oxidative stress, and hormonal imbalances. Chemical contaminants in water and work exposures, including heavy metals, dioxins, and PCBs, disrupt the hormonal regulation and potentially contribute to endometriosis. Mitigating the environmental impact of pollution is required to safeguard women’s reproductive health. This requires a comprehensive approach involving stringent environmental regulations, sustainable practices, responsible waste management, research and innovation, public awareness, and collaboration among stakeholders.ConclusionPublic health policies have a major role in addressing the interaction between pollution and endometriosis in a long‐term commitment.

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“…Lipophilicity and hydrophobicity are directly related to molecular weight, and increasing molecular weight increases these properties. The relationship between molecular weight and hydrophobicity in high molecular weight (HMW) PAHs such as benzo [a] pyrene, indeno [1, 2, 3-cd] pyrene, and dibenzo [ah] anthracene is more noticeable than PAHs such as naphthalene and phenanthrene that have low molecular weight (LMW) (Barbosa Jr et al, 2023). In addition, PAHs can be used in environmental sampling in which ecological parameters are collected (Alegbeleye, Opeolu, & Jackson, 2017;Tong, Chen, Liu, Wang, & Tian, 2019).…”

Section: Classification Of Pahsmentioning

confidence: 99%

Mutagenic and genotoxic effect of polycyclic aromatic hydrocarbons on health: Mechanisms and Risk assessment

Zahed

Salehi²,

Tanhaie

et al. 2023

Preprint

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Polycyclic aromatic hydrocarbons (PAHs) contain a large group of chemical compounds that have two or more aromatic rings in their structure. These materials are produced from the incomplete burning of organic materials (such as oil, coal, wood, etc.). Natural and human activities have caused these substances to widely enter the human life cycle and affect the body’s health and functioning. After entering the body, these substances accumulate in the lungs, brain, and fat tissue, therefore, due to the high-fat mass in women, this group is more vulnerable to PAH. With the increased concentration of many of these substances in the body, problems such as genetic toxicity, carcinogenesis and mutagenesis occur. In addition to a general look at these damages, specifically how the mutagenesis process and its effects on the body are examined in detail. PAHs can become more active metabolites (BP-7-trans-dihydrodiol, benzo [a] pyrene diol-epoxide) bind to DNA, and cause mutations in DNA strands by producing ROS. PAHs produce harmful metabolites by regulating the activity of xenobiotic pathway enzymes (cytochrome P450, epoxide hydrolase, and peroxidases). For all the above, it is necessary to investigate the mechanism of their effect on the body. Due to the importance of this issue, detailed and comprehensive information is not available in sufficient quantity in this case, thus, in this research, it has been mentioned in detail and at the end of their risk assessment, it has also been examined.

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Polycyclic aromatic hydrocarbons (PAHs): Updated aspects of their determination, kinetics in the human body, and toxicity

Cited by 77 publications

References 261 publications

A Key to Crystallinity and Reusability of Covalent Organic Frameworks: Adsorption-Induced Deformation

A Key to Crystallinity and Reusability of Covalent Organic Frameworks: Adsorption-Induced Deformation

Pollution and endometriosis: A deep dive into the environmental impacts on women's health

Mutagenic and genotoxic effect of polycyclic aromatic hydrocarbons on health: Mechanisms and Risk assessment

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