Polycyclic musk compounds in higher trophic level aquatic organisms and humans from the United States

Kannan, Kurunthachalam; Reiner, Jessica L.; Yun, Se Hun; Perrotta, Emily; Lin, Tao; Johnson‐Restrepo, Boris; Rodan, Bruce D.

doi:10.1016/j.chemosphere.2005.03.041

Cited by 218 publications

(96 citation statements)

References 22 publications

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“…These accumulation characteristics were similar to those reported in fish tissues by Duedahl-Olesen et al [28]. Kannan [12] also found no relationship between gender and the concentrations of HHCB or AHTN in human fat samples. However, Hutter et al [20] observed that plasma concentrations of HHCB were significantly higher in the blood of women than those in men, and they attributed this difference to the more frequent use of creams, body lotions, and perfumes by women than men.…”

Section: Gender and Agesupporting

confidence: 90%

“…Chem. 29, 2010 1881 ($4) was obtained in human fat samples collected from Austria by Kannan [12]. Peck and Hornbuckle [34] reported that the concentration ratio of HHCB to AHTN in Lake Michigan (USA) waters was 4.7.…”

Section: Geographical Trendsmentioning

confidence: 99%

“…In recent years, more and more studies have reported the occurrence of nitro-and polycyclic musk fragrances in various environmental matrixes, such as sewage sludge, air, wastewater, and sediment [8][9][10][11] as well as fish, human tissues, mother's milk [12][13][14][15], and others. However, there is little information about temporal trends of synthetic musk compounds concentrations in human blood that may reflect the changes in use of these compounds by the industry and alterations in the patterns of consumer use of perfumed products.…”

Section: Introductionmentioning

confidence: 99%

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Occurrence of synthetic musk fragrances in human blood from 11 cities in China

Shi

Niu

et al. 2010

Enviro Toxic and Chemistry

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Abstract-We measured two nitro musk fragrances (musk xylene) and musk ketone) and five polycyclic musk fragrances (galaxolide [HHCB], tonalide [AHTN], celestolide [ADBI], traseolide [ATII], and phantolide [AHMI]) in human blood samples from 11 cities of China (n ¼ 204). Possible temporal trends in musk concentrations and associations with personal factors, such as gender, age, and others, were studied. Galaxolide (HHCB) showed the highest median concentration (0.85 ng/g) followed by AHTN (0.53 ng/g) with high detection frequency (91 and 77%, respectively). Concentrations of the other synthetic musk fragrances, including musk ketone and musk xylene, were all below the quantification limits. The results suggested that musk concentrations were not significantly relative to gender and body weight but positively correlated with age groups and locations. Apparent differences were also observed in the ratios of HHCB to AHTN concentrations among different cities.

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Section: Gender and Agesupporting

confidence: 90%

Section: Geographical Trendsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Occurrence of synthetic musk fragrances in human blood from 11 cities in China

Shi

Niu

et al. 2010

Enviro Toxic and Chemistry

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“…9, 5.7, 4.3, and 4.9, respectively], SM are expected to bio-accumulate in aquatic biota. Previous studies have shown widespread occurrence of SM in aquatic biota including fish, crustaceans and mussels (Kannan et al 2005;Wan et al 2007), as well as top order predators such as sharks, seals, and finless porpoises (Nakata 2005). SM have also been detected in human adipose tissues (Müller et al 1996), blood plasma (Hutter et al 2005), and human breast milk (Duedahl-Olesen et al 2005;Reiner et al 2007;Zhang et al 2011).…”

Section: Introductionmentioning

confidence: 90%

Screening level ecological risk assessment for synthetic musks in surface water of Lake Taihu, China

Guo

et al. 2012

Stoch Environ Res Risk Assess

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A total of thirty-three surface water samples were collected from Meiliang Bay, Gonghu Bay and Xukou Bay of Lake Taihu, and analyzed for synthetic musks, including 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylcyclopenta-[c]-2-benzopyrane (HHCB), 7-acetyl-1,1,3,4,4, 6-hexamethyl-1,2,3,4-tetrahydronaphthalene (AHTN), 1-tertbutyl-3,5-dimethyl-2,5-dinitro-4-acetylbenzene (MK) and 1-tert-butyl-3,5-dimethyl-2,4,6-trinitrobenzene (MX). Ecological risks of these compounds were characterized by hazard quotient (HQ) method due to a lack of sufficient available toxicity data of synthetic musks. HHCB was the main synthetic musk detected in Lake Taihu, followed by AHTN, MK, and MX. The risk assessment results indicate that low ecological risks were posed by HHCB and total synthetic musks, and even lower risks posed by other synthetic musks in the worst case; much lower ecological risks were caused by both individual and total synthetic musks in the general case. The combined ecological risk from total synthetic musks calculation suggests that the combined ecological risk from all four synthetic musks was expected to be slightly higher than for the individual musks due to their joint action. The HQ spatial distribution maps show that several hot-spot areas were mainly around the river inlets to Lake Taihu, indicating that synthetic musks may be transported to Lake Taihu with municipal sewage and industrial wastewater from surrounding areas. However, the ecological risks in hot-spot areas posed by individual and total synthetic musks were still acceptable.

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“…Also in China, elevated residue levels of commonly used pharmaceuticals have been detected in surface wastewater treatment plants as well as in surface waters (Duan et al 2013;Wolf et al 2013;Yang et al 2015;Zhou et al 2014). Like POPs, some of these substances have a potential for bioaccumulation (Kannan et al 2005). Besides, common applied antibiotics used in human therapy and intensive livestock farming can produce selection pressure possibly resulting in resistant bacteria which in turn may endanger human health (Zhang et al 2009).…”

Section: Introductionmentioning

confidence: 99%

Depth profile of persistent and emerging organic pollutants upstream of the Three Gorges Dam gathered in 2012/2013

Deyerling

Wang

et al. 2015

Environ Sci Pollut Res

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Persistent and emerging organic pollutants were sampled in September 2012 and 2013 at a sampling site in front of the Three Gorges Dam near Maoping (China) in a water depth between 11 and 61 m to generate a depth profile of analytes. A novel compact water sampling system with self-packed glass cartridges was employed for the on-site enrichment of approximately 300 L of water per sample to enable the detection of low analytes levels in the picogram per liter-scale in the large water body. The overall performance of the sampling system was acceptable for the qualitative detection of polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs), organochlorine pesticides (OCPs), perfluoroalkylic acids (PFAAs), pharmaceutical residues and polar pesticides. Strongly particle-associated analytes like PAHs and PCBs resided mainly in the glass wool filter of the sampling system, whereas all other compounds have mainly been enriched on the XAD-resin of the selfpacked glass cartridges. The sampling results revealed qualitative information on the presence, depth distribution and origin of the investigated compounds. Although the depth profile of PAHs, PCBs, OCPs, and PFAAs appeared to be homogeneous, pharmaceuticals and polar pesticides were detected in distinct different patterns with water depth. Source analysis with diagnostic ratios for PAHs revealed their origin to be pyrogenic (burning of coal, wood and grass). In contrast, most PCBs and OCPs had to be regarded as legacy pollutants which have been released into the environment in former times and still remain present due to their persistence. The abundance of emerging organic pollutants could be confirmed, and their most abundant compounds could be identified as perfluorooctanoic acid, diclofenac and atrazine among investigated PFAAs, pharmaceuticals and polar pesticides, respectively.

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Polycyclic musk compounds in higher trophic level aquatic organisms and humans from the United States

Cited by 218 publications

References 22 publications

Occurrence of synthetic musk fragrances in human blood from 11 cities in China

Occurrence of synthetic musk fragrances in human blood from 11 cities in China

Screening level ecological risk assessment for synthetic musks in surface water of Lake Taihu, China

Depth profile of persistent and emerging organic pollutants upstream of the Three Gorges Dam gathered in 2012/2013

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