Polyfunctionalized Aryllead Triacetates in a Cascade Synthesis of Tetracyclic Isochromanocoumarin-Type Compounds

Abstract

The three-step one-pot a-arylation-annulation sequence leading to the reaction of 4-hydroxycoumarins with in situ generated 2-(bromomethyl)aryllead triacetates carried out in the presence of a combination of ortho-phenantroline-potassium tert-butoxide afforded tetracyclic benzo [b]pyran compounds in good to high yields.