Polyhalogenated heterocyclic compounds. Part 44. Reactions of perfluoro-(4-isopropylpyridine) with oxygen nucleophiles

Abstract

Reactions between perfluoro-(4-isopropyl pyridine) 1 and a variety of oxygen nucleophiles gave mono, di-and tri-alkoxylated systems depending on reaction conditions. The barrier to rotation for the perfluoro-isopropyl group in several pyridine systems was measured by 19 F n.m.r. saturation transfer experiments.