Polymer-coated magnetic nanoparticles for rapid bioassay of 90Sr in human urine samples

Varve, Zack; Lai, Edward P. C.; Li, Chunsheng; Sadi, Baki; Kramer, Gary H.

doi:10.1007/s10967-012-1621-5

Cited by 5 publications

(1 citation statement)

References 10 publications

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“…15 Additionally, MNPs have been coated with polymers and then treated with 18-crown-6 crown ether to form extraction chromatographic resins with magnetic properties; these materials have been evaluated as a means of collecting 90 Sr from various sample matrices. 16–18 Much work has been conducted in the use of mesoporous silica containing entrained magnetic iron oxide NPs to form nanocomposites that are used in the capture of metals 19–21 and uranium. 22,23 Recently, MNPs treated with various chelators for actinide extraction were reviewed.…”

Section: Introductionmentioning

confidence: 99%

Magnetic iron oxide and manganese-doped iron oxide nanoparticles for the collection of alpha-emitting radionuclides from aqueous solutions

et al. 2016

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Magnetic nanoparticles are well known to possess chemically active surfaces and large surface areas that can be employed to extract a range of ions from aqueous solutions. Additionally, their superparamagnetic properties provide a convenient means for bulk collection of the material from solution after the targeted ions have been adsorbed. Herein, two nanoscale amphoteric metal oxides, each possessing useful magnetic attributes, were evaluated for their ability to collect trace levels of a chemically diverse range of alpha emitting radioactive isotopes (polonium (Po), radium (Ra), uranium (U), and americium (Am)) from a wide range of aqueous solutions. The nanomaterials include commercially available magnetite (Fe3O4) and magnetite modified to incorporate manganese (Mn) into the crystal structure. The chemical stability of these nanomaterials was evaluated in Hanford Site, WA ground water between the natural pH (~8) and pH 1. Whereas the magnetite was observed to have good stability over the pH range, the Mn-doped material was observed to leach Mn at low pH. The materials were evaluated in parallel to characterize their uptake performance of the alpha-emitting radionuclide spikes from ground water across a range of pH (from ~8 down to 2). In addition, radiotracer uptake experiments were performed on Columbia River water, seawater, and human urine at their natural pH and at pH 2. Despite the observed leaching of Mn from the Mn-doped nanomaterial in the lower pH range, it exhibited generally superior analyte extraction performance compared to the magnetite, and analyte uptake was observed across a broader pH range. We show that the uptake behavior of the various radiotracers on these two materials at different pH levels can generally be explained by the amphoteric nature of the nanoparticle surfaces. Finally, the rate of sorption of the radiotracers on the two materials in unacidified ground water was evaluated. The uptake curves generally indicate that equilibrium is obtained within a few minutes, which is attributed to the high surface areas of the nanomaterials and the high level of dispersion in the liquids. Overall, the results indicate that these nanomaterials may have the potential to be employed for a range of applications to extract radionuclides from aqueous solutions.

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