Polymer-hydroxyapatite composites for biodegradable bone fillers

Calcium orthophosphate-based biocomposites and hybrid biomaterials

“…In other studies, PLA and PGA fibers were combined with porous HA scaffolds. Such reinforcement did not hinder bone ingrowth into the implants, which supported further development of such biocomposites as bone graft substitutes [47,48,309,330,331].…”

Fracture Mechanisms of Biodegradable PLA and PLA/PCL Blends

“…Poly (lactic acid) (PLA), made from natural resources such as starch of plants, is one of typical biodegradable thermoplastic polymers and has extensively been used in medical fields such as orthopedics, neurosurgery and oral surgery as bone fixation devices mainly due to biocompatibility and bioabsorbability (Higashi et al, 1986;Ikada et al, 1996;Middleton & Tipton, 2000;Mohanty, 2000). Its importance has led to many studies on its mechanical properties and fracture behavior which found that the mode I fracture behavior of PLA is relatively brittle in nature (Todo et al, 2002;Park et al, 2004Park et al, , 2005Park et al, , 2006.…”

Characterization of Correlation between Microstructure and Fracture Properties of Poly(lactic acid) Polymer Blends

“…Poly (lactic acid) (PLA) is one of the typical biodegradable polymers, which has been considered for the use in a variety of industrial fields, including automobile, computer and electric appliances. PLA has also been used as an implant biomaterial in medical fields such as orthopedics and oral surgery [1,2]. Its importance has led to many studies on its mechanical properties and fracture behavior [3][4][5][6][7] which found that the fracture behavior of PLA is relatively brittle in nature.…”