Polymer nanocomposites for biomedical applications

Shahbaz, Areej; Hussain, N.; Mahmood, Tehreem; Iqbal, Hafiz M.N.; Emran, Talha Bin; Show, Pau Loke; Bilal, Muhammad

doi:10.1016/b978-0-323-91611-0.00012-8

Cited by 4 publications

(2 citation statements)

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“…Glushkova органов кровеносной системы [1,2]. Несмотря на высокую биосовместимость и функциональность, такие материалы часто требуют дополнительного модифицирования [3], например, введение различных наночастиц может существенно изменить структуру полимерной матрицы и, как следствие, улучшить свойства материала [4,5]. Углеродные наноматериалы, благодаря высокой прочности на разрыв, обусловленной уникальной организацией атомов углерода в двумерной гексагональной решетке, представляют особый интерес для разработки имплантируемых медицинских изделий [6,7].…”

Section: список сокращенийunclassified

Biocompatible Elastic Polymer Nanocomposites Based on Multiwalled Carbon Nanotubes for Application in Cardiovascular Surgery

Rezvova,

Nikishau,

Kostyuk

et al. 2023

Kompleks. probl. serdečno-sosud. zabol.

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HighlightsThe incorporation of multi-walled carbon nanotubes into the structure of the poly(styrene-block-isobutylene-block-styrene) polymer matrix leads to an increase in the tensile strength and Young's modulus of the nanocomposites. The resulting nanocomposites retain high biocompatibility and can be used as elements of implanted cardiovascular products. AbstractAim. To synthesize and modify poly(styrene-block-isobutylene-block-styrene) (SIBS) with two types of multi-walled carbon nanotubes (MWCNTs) in different concentrations to improve its mechanical properties.Methods. SIBS was synthesized by controlled cationic polymerization. Polymer nanocomposites were prepared using ultrasonic dispersion followed by casting films from a polymer solution. The resulting nanocomposite films were subjected to mechanical tests under uniaxial tensile conditions. Tensile strength, elastic-strain properties, and plastic deformation under cyclic loading were assessed. The structure of the nanocomposites was analyzed by scanning electron microscopy. The hydrophilicity of the surface of the materials was studied by measuring the contact angle with water. The cytotoxicity of the resulting polymer films was assessed by the viability and metabolic activity of endothelial cells cultured on the surface of the nanocomposites.Results. Polymer nanocomposites with a uniform distribution of MWCNTs in the polymer matrix were obtained. SIBS films modified with 1% MWCNTs with a diameter of 50–90 nm showed an increase in tensile strength by 16.4% compared to SIBS polymer. Increasing the concentration of MWCNTs to 8% led to a decrease in the strength of polymer materials by 19,6%. The inclusion of nanoparticles into the polymer matrix significantly increased the Young's modulus of the studied polymers with a MWCNT content above 4%. With an increase in the content of MWCNTs in the nanocomposites, an increase in hydrophilicity was also observed, while the cytotoxicity of the samples towards endothelial cells was not noted.Conclusion. Nanocomposites based on SIBS and MWCNTs, due to their high strength and biocompatibility, can become a promising material for the development of various medical products, in particular prosthetic heart valves.

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Section: список сокращенийunclassified

Biocompatible Elastic Polymer Nanocomposites Based on Multiwalled Carbon Nanotubes for Application in Cardiovascular Surgery

Rezvova,

Nikishau,

Kostyuk

et al. 2023

Kompleks. probl. serdečno-sosud. zabol.

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“…They are abundant and cheap, and their synthesis is less complex and costly than that of clay minerals. Shahbaz et al [142] outlined the advantages and disadvantages of using nanoclays in biomedical applications. The main disadvantages are high viscosity, agglomeration, and non-uniform distribution.…”

Section: Clay Minerals In Healthcarementioning

confidence: 99%

Physical-Chemical Properties of Nano-Sized Phyllosilicates: Recent Environmental and Industrial Advancements

Elmi

2023

Encyclopedia

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Phyllosilicates are common minerals that include the most widely known micas and clay minerals. These minerals are found in several natural environments and have unique physical-chemical features, such as cation exchange capacity (CEC) and surface charge properties. When phyllosilicates are nano-sized, their physical-chemical properties are enhanced from those of the micro-sized counterpart. Because of their unique crystal chemical and physical-chemical features, kinetics, and particle size, nano-sized clay minerals (i.e., kaolinite, montmorillonite/illite) and micas (i.e., muscovite) are of great interest in several fields spanning from environmental applications to engineered materials. This paper aims to overview the recent developments of environmental protection and technological applications employing nano-sized natural micas and clay minerals. Emphasis is given to the role that the unique physical-chemical properties of montmorillonite, vermiculite, kaolinite, and muscovite play in nanoparticle formulations, manufacture, and technical performance.

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