Polymeric Nanoparticles for Transdermal Delivery of Polyphenols

Murthy, Namratha Turuvekere Vittala; Paul, Sagar Kumar; Chauhan, Harsh; Singh, Somnath

doi:10.2174/1567201818666210720144851

Cited by 11 publications

(3 citation statements)

References 57 publications

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“…Nanoemulsions, for instance, create nanoscale droplets of polyphenols within a continuous phase, enhancing their stability and solubility (Huang et al, 2010). Nanoparticles, on the other hand, enable precise control over the release of polyphenols, facilitating targeted delivery in cosmetic formulations (Vittala Murthy et al, 2022). Nanoliposomes, consisting of lecithin, water, and cholesterol, are one of the commercialized nanocosmetic products (Ajazzuddin et al, 2015) and they could encapsulate several bioactive compounds.…”

Section: Bioengineered-based Strategies For Polyphenol Encapsulationmentioning

confidence: 99%

An extensive review on phenolic compounds and their potential estrogenic properties on skin physiology

Rispo,

De Negri Atanasio,

Demori

et al. 2024

Front. Cell Dev. Biol.

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Polyphenolic compounds constitute a diverse group of natural components commonly occurring in various plant species, known for their potential to exert both beneficial and detrimental effects. Additionally, these polyphenols have also been implicated as endocrine-disrupting (ED) chemicals, raising concerns about their widespread use in the cosmetics industry. In this comprehensive review, we focus on the body of literature pertaining to the estrogenic properties of ED chemicals, with a particular emphasis on the interaction of isoflavones with estrogen receptors. Within this review, we aim to elucidate the multifaceted roles and effects of polyphenols on the skin, exploring their potential benefits as well as their capacity to act as ED agents. By delving into this intricate subject matter, we intend to provoke thoughtful consideration, effectively opening a Pandora’s box of questions for the reader to ponder. Ultimately, we invite the reader to contemplate whether polyphenols should be regarded as friends or foes in the realm of skincare and endocrine disruption.

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Section: Bioengineered-based Strategies For Polyphenol Encapsulationmentioning

confidence: 99%

An extensive review on phenolic compounds and their potential estrogenic properties on skin physiology

Rispo,

De Negri Atanasio,

Demori

et al. 2024

Front. Cell Dev. Biol.

View full text Add to dashboard Cite

show abstract

“…Sankha Bhattacharya’s study showed that polymeric nanoparticles conjugated with anti-EGFR monoclonal antibody and 5-fluorouracil (5-FU) had higher cellular uptake and higher cytotoxicity, and thereby have a good therapeutic effect on EGFR-positive colorectal cancer (Bhattacharya 2021 ). In addition, as a novel therapy polymeric nanoparticles was used to deliver low solubility and low bioavailability polyphenols for the treatment of skin cancers, such as melanoma (Vittala Murthy et al 2022 ) (Table 2 ).…”

Section: Properties Of Nanoparticles and Their Applications In Tumorsmentioning

confidence: 99%

Nanoparticles advanced from preclinical studies to clinical trials for lung cancer therapy

et al. 2023

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Lung cancer is the leading cause of cancer mortality. As a heterogeneous disease, it has different subtypes and various treatment modalities. In addition to conventional surgery, radiotherapy and chemotherapy, targeted therapy and immunotherapy have also been applied in the clinics. However, drug resistance and systemic toxicity still cannot be avoided. Based on the unique properties of nanoparticles, it provides a new idea for lung cancer therapy, especially for targeted immunotherapy. When nanoparticles are used as carriers of drugs with special physical properties, the nanodrug delivery system ensures the accuracy of targeting and the stability of drugs while increasing the permeability and the aggregation of drugs in tumor tissues, showing good anti-tumor effects. This review introduces the properties of various nanoparticles including polymer nanoparticles, liposome nanoparticles, quantum dots, dendrimers, and gold nanoparticles and their applications in tumor tissues. In addition, the specific application of nanoparticle-based drug delivery for lung cancer therapy in preclinical studies and clinical trials is discussed.

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“…Certainly, the synthesis methods of these nanoparticles, which directly affect their properties, will also indirectly determine the effectiveness of nanoparticles in combating the new coronavirus. The sizes of nanoparticles, which are generally between 1 and 100 nanometers, guarantee a very high surface to volume ratio, as well as the ability to load significant amounts of drugs in small amounts of nanoparticles, which can help a lot in combating pathogens, including SARS-CoV-2 virus [67].…”

Section: Different Classes Of Nanomaterials Against Coronavirus Diseasementioning

confidence: 99%

Nanoparticles for Coronavirus Control

Akbarian

Uversky

2022

Nanomaterials

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More than 2 years have passed since the SARS-CoV-2 outbreak began, and many challenges that existed at the beginning of this pandemic have been solved. Some countries have been able to overcome this global challenge by relying on vaccines against the virus, and vaccination has begun in many countries. Many of the proposed vaccines have nanoparticles as carriers, and there are different nano-based diagnostic approaches for rapid detection of the virus. In this review article, we briefly examine the biology of SARS-CoV-2, including the structure of the virus and what makes it pathogenic, as well as describe biotechnological methods of vaccine production, and types of the available and published nano-based ideas for overcoming the virus pandemic. Among these issues, various physical and chemical properties of nanoparticles are discussed to evaluate the optimal conditions for the production of the nano-mediated vaccines. At the end, challenges facing the international community and biotechnological answers for future viral attacks are reviewed.

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Polymeric Nanoparticles for Transdermal Delivery of Polyphenols

Cited by 11 publications

References 57 publications

An extensive review on phenolic compounds and their potential estrogenic properties on skin physiology

An extensive review on phenolic compounds and their potential estrogenic properties on skin physiology

Nanoparticles advanced from preclinical studies to clinical trials for lung cancer therapy

Nanoparticles for Coronavirus Control

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