Polymorphous Low-Grade Adenocarcinoma––Management and Reconstruction with Temporalis Myofacial Flap

Vinod, Vivek; Mani, Varghese; George, Arun; Sivaprasad, K.

doi:10.1007/s12663-011-0227-8

Cited by 5 publications

(2 citation statements)

References 16 publications

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“…Polymorphous low-grade adenocarcinoma is a rare, malignant salivary gland tumor, which is found almost exclusively in minor salivary glands. It is more frequent in the third to seventh decade of life, with a clear female predilection in a 2:1 ratio [ 6 ] Most of the lesions occur in the palate. Other intraoral sites can be buccal mucosa, retromolar region, upper lip, and base of the tongue.…”

Section: Discussionmentioning

confidence: 99%

An Extremely Rare Case of Synchronous Low-Grade Polymorphous Adenocarcinoma With Canalicular Adenoma of the Minor Salivary Gland of the Palate

Kasthurirengan¹,

John²

2023

Cureus

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Tumors of the salivary gland are a group of complex, heterogeneous lesions that are located either in the parotid gland, submandibular gland, sublingual gland, or minor salivary glands. These tumors have a wide range of etiology, pathophysiology, treatment, and prognosis. Multiple salivary gland tumors are extremely rare and usually occur more commonly in major salivary glands than in minor glands. A 61-year-old man with a chief complaint of swelling in the upper jaw for the past eight years reported to the department of oral and maxillofacial surgery. Incisional biopsy revealed a canalicular adenoma (CA) of the minor salivary gland of the palate. Wide local excision was done with closure using a buccal pad of fat and a collagen sheet. Surprisingly, the excisional biopsy was suggestive of synchronous low-grade polymorphous adenocarcinoma (PAC) with CA of the minor salivary gland of the palate. This appears to be the first reported case of PAC with CA found in the palate.

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Section: Discussionmentioning

confidence: 99%

An Extremely Rare Case of Synchronous Low-Grade Polymorphous Adenocarcinoma With Canalicular Adenoma of the Minor Salivary Gland of the Palate

Kasthurirengan¹,

John²

2023

Cureus

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“…Regarding the prevalence of anatomical sites affected by PAC, although the buccal mucosa is a less-considered site, it is not uncommon. PAC is usually diagnosed in the fifth decade of an individual’s life and is more common in females compared to males, with a ratio of 2:1 [ 6 ]. Typically, it manifests as mucosal swelling, and most patients remain asymptomatic.…”

Section: Introductionmentioning

confidence: 99%

Polymorphous Adenocarcinoma: A Systematic Review of the Literature and Presentation of Two Cases in a Less-Considered Anatomical Site

Mauceri,

Coppini,

Alecci

et al. 2024

Cancers

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Background: Polymorphous adenocarcinoma (PAC) is the second-most common malignant tumour of the minor salivary glands. Although PAC predominantly affects the palate, it can also involve the buccal mucosa. This systematic review aims to investigate the literature data about PAC. Furthermore, we report two cases of patients affected by PAC in an infrequently considered anatomical site. Methods: According to PRISMA guidelines, a systematic review search was conducted on PubMed, Scopus, and Web of Science. Observational studies conducted on patients with a histological diagnosis of PAC were selected and analysed. Furthermore, two cases of patients with PAC affecting the buccal mucosa were reported. Results: Twenty-nine studies were included, and 143 patients affected by PAC were analysed (62 males, 75 females, and 6 undefined, with a mean age of 57.4 ± 14.5 years). The palate was the most affected site (99/143, 69.2%), followed by the buccal mucosa (12/143, 8.4%). Moreover, we report two cases of patients with PAC affecting the buccal mucosa (one male and one female, with a mean age of 70.5 ± 2.5 years). Conclusions: The present study underscores the importance of considering the buccal mucosa as a possible location of minor salivary gland tumours; although it is a less-considered affliction, it is not uncommon.

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Polymorphous adenocarcinoma of the upper lip: A case report

Ketheeswaranathan

Andi

2022

Advances in Oral and Maxillofacial Surgery

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Polymorphous Low-Grade Adenocarcinoma––Management and Reconstruction with Temporalis Myofacial Flap

Cited by 5 publications

References 16 publications

An Extremely Rare Case of Synchronous Low-Grade Polymorphous Adenocarcinoma With Canalicular Adenoma of the Minor Salivary Gland of the Palate

An Extremely Rare Case of Synchronous Low-Grade Polymorphous Adenocarcinoma With Canalicular Adenoma of the Minor Salivary Gland of the Palate

Polymorphous Adenocarcinoma: A Systematic Review of the Literature and Presentation of Two Cases in a Less-Considered Anatomical Site

Polymorphous adenocarcinoma of the upper lip: A case report

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