Polyphenol and nutrient release from skin of almonds during simulated human digestion

Selected primary and secondary metabolites in fresh persimmon (Diospyros kaki Thunb.): A review of analytical methods and current knowledge of fruit composition and health benefits

“…As regards the former group (i.e. benzoic acid derivatives, monomeric flavanols, flavonols and flavanones) the availability for absorption during in vitro human digestion has been suggested (Mandalari et al, 2010). Likewise, in some in vitro experiments, proanthocyanidin dimers and trimers, but not polymers with an average DP= 7, were absorbed by human intestinal epithelium cells (Déprez, Mila, Huneau, Tome, & Scalbert, 2001); proanthocyanidin polymers were not absorbed even by chicken or sheep (JimenezRamnsey, Rogler, Housley, Butler, & Elkin, 1994;Terrill, Waghorn, Woolley, McNabb, & Barry, 1994).…”

Immunomodulatory and antiviral activity of almond skins

“…Webb) are known to have a number of nutritional benefits, mainly based on the presence of polyphenols and the high dietary fiber content [13]. We have recently shown that polyphenols from almond skin are bioaccessible in the upper gastrointestinal (GI) tract and therefore potentially available for absorption during digestion [14]. Blanched almond skins industrially removed from the nut by hot water blanching constitute 4-8% of the total shelled almond weight and are considered as by-products, which if not processed further, are discarded as waste.…”

How Can Research on Plants Contribute to Promoting Human Health?

“…Differences in bioavailability determined by differences in the food matrix would be reflected by different levels of the phytonutrients or their metabolites in plasma or urine of animals. Differences in bioavailability potentially determined by the food matrix could be investigated further using model gut technology or cell-based systems that report adsorption such as CaCo2 cells (Mandalari et al, 2008a(Mandalari et al, , 2008b(Mandalari et al, , 2010Cencic and Langerholc, 2010).…”