Polyphenol composition and antioxidant activity of Searsia tripartita and Limoniastrum guyonianum growing in Southeastern Algeria

Hadjadj, Soumia; Esnault, Marie-Andrée; Berardocco, Solenne; Guyot, Sylvain; Bouchereau, Alain; Ghouini, Fatima; Lamini, Razika; Hadj-Khelil, Aminata Ould El

doi:10.1016/j.sciaf.2020.e00585

Cited by 8 publications

(3 citation statements)

References 45 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The phytochemical profile was achieved using complementary techniques for the phytochemical compound's identification and quantification. The polyphenols play an important role in the antioxidant activity because these types of compounds have aromatic rings that allow them to act as reducing agents due to their phenolic hydrogen atoms' mobility, stabilization, and relocation of the unpaired electrons of their structures and due to their metal chelating properties [42]. The extraction process, using 50% ethanol, allowed us to obtain an extract enriched in polyphenols.…”

Section: Discussionmentioning

confidence: 99%

Phytochemical Screening and Antioxidant Potential of Selected Extracts from Betula alba var. pendula Roth., Glycyrrhiza glabra L., and Avena sativa L.

Ghica,

Drumea,

Moroșan

et al. 2023

Plants

View full text Add to dashboard Cite

The aim of the present study was to obtain, characterize, and evaluate the antioxidant potential of some extracts obtained from the bark of Betula alba var. pendula Roth., the root of Glycyrrhiza glabra L., and the green herb of the Avena sativa. The results revealed that the lowest IC50 value, determined by all three methods, was obtained for Betulae extractum (BE) (73.6 µg/mL—DPPH method, 11.2 µg/mL—ABTS method, and 58.7 µg/mL—FRAP method), followed by Liquiritiae extractum (LE) (805.6 µg/mL, 92.1 µg/mL, and 722 µg/mL) and Avenae extractum (1.13 mg/mL—DPPH method, 99.7 µg/mL—ABTS method, and 135.1 µg/mL—FRAP method). These results correlate with total polyphenols content (expressed in g tannic acid/100 g dry extract), with BE having more polyphenols than LE and AE (47.96 ± 9.7083 for BE, compared with 9.31 ± 0.9913 for LE and 40.55 ± 6.3715 for AE). The total flavonoid content (expressed as g rutoside/100 g dry extract) is similar for BE and LE (3.75 ± 0.3140 and 3.44 ± 0.3037) and smaller for AE (1.95 ± 0.0526). Therefore, Betulae extractum has the strongest antioxidant action, with an IC50 value very close to the standard used as a reference (ascorbic acid—16.5 μg/mL solution). The FT-ICR-MS analysis confirmed the presence of the major compounds in all three extracts. The antioxidant properties of the studied extracts were further supported by molecular docking experiments that revealed the potential of the analyzed phytochemicals to act as both noncovalent and covalent activators of the Nrf2 signaling pathway, with promising benefits in treating various skin disorders.

show abstract

Section: Discussionmentioning

confidence: 99%

Phytochemical Screening and Antioxidant Potential of Selected Extracts from Betula alba var. pendula Roth., Glycyrrhiza glabra L., and Avena sativa L.

Ghica,

Drumea,

Moroșan

et al. 2023

Plants

View full text Add to dashboard Cite

show abstract

“…Various methods have been proposed to study the antioxidant activity of extracts, as a single method cannot fully assess the antioxidant potential of natural extracts due to the complexity of the oxidation process and the chemical diversity of antioxidants, with lipophilic and hydrophilic compounds [21,37,38]. In the present study, different in vitro assays were used in order to determine the antioxidant activity of Salvia balansae leaves polyphenolic extract, namely DPPH and 2,2-azinobis (3-ethylbenzothiazoline6-sulfonic acid (ABTS) radicals scavenging assays, ferric reducing antioxidant power (FRAP) and iron chelation activity.…”

Section: Antioxidant Activity Of S Balansae Leaves Polyphenolic Extractmentioning

confidence: 99%

HPLC-DAD Screening and Antioxidant Activity of Phenolic Compounds of Salvia balansae de Noé Leaves Extract

Malik MAHDJOUB,

BENZITOUNE,

MAIZ

et al. 2023

jrp

View full text Add to dashboard Cite

Salvia balansae de Noé is known to be an important source of a wide variety of non-toxic bioactive compounds with lack of information hinders exploitation in food and pharmaceutical industries as natural antioxidants. In this work, the phenolic compounds from S. balansae leaves were extracted using an ultrasound-assisted methodology and were separated and identified by HPLC-DAD. The antioxidant activity was evaluated by ABTS, and DPPH scavenging assays, Iron (Fe 2+ ) Chelating ability and reducing power (FRAP) tests. The total phenolic compounds (TPC) and total flavonoid content (TFC) were found with amounts of 49.63 ± 6.31 mg GAE/g DW and 8.14 ± 0.39 mg QE/g DW respectively. The ABTS, DPPH assays and metal chelating ability test demonstrated a higher antioxidant properties with IC50 values of 328.95 ± 5.29 µg/mL, 545.03 ± 3.27 µg/mL and 689.40 ± 0.86 µg/mL respectively. The reducing power at 700 nm increased considerably with concentration. In addition, the HPLC-DAD analysis showed that there were twelve detectable phenolic compounds and the benzoic acid, quercetin, myrecetin, hydroxyflavon, and ascorbic acid have been exclusively identified for the first time in S. balansae leaves extract and are rarely determined in other Salvia L. species. Therefore, these results provided new data about the main phenolic compounds present in S. balansae leaves extract with a strong antioxidant potential, which will be an alternative source for synthetic compounds.

show abstract

“…Antioxidants are naturally substances present in fruits, vegetables and medicinal plants which have the ability to trappe or neutralise free radicals (Schramm et al, 2003;Santos-Sánchez et al, 2019;Phuyal et al, 2020). Algeria possesses a rich and a little valued flora that must be studied and charachterised from its biological and chemical activities (Benyagoub et al, 2020;Hadjadj et al, 2020). Globularia alypum L., locally named «Tasselgha», is a wild plant belonging to the Globulariaceae family.…”

Section: Introductionmentioning

confidence: 99%

Antihemolytic and antioxidant activities of aerial parts extracts of Zygophyllum album L. and Globularia alypum L. from Algeria

Khaoula OUFFAI,

Rachid AZZI,

Fayza ABBOOU

et al. 2022

jnpra

View full text Add to dashboard Cite

The main intrest of this study was to evaluate the antihemolytic and the antioxidant activities of the aqueous extracts of Globularia alypum and Zygophyllum album prepared by three different methods: decoction, infusion and maceration. Phytochemical tests, total phenolic, flavonoid and tannins contents of the different aqueous extracts were determined. DPPH radical scavenging assay and Ferric Reducing Antioxidant Power (FRAP) were employed for the evaluation of the antioxidant activity. Whereas, the antihemolytic activity was carried out by the evaluation of the protective effect of the various prepared extracts on red blood cells against the radical attack induced by 2,2′-azobis(2-amidinopropane) di-hydrochloride (AAPH). The aqueous extract of Globularia alypum prepared by decoction showed the highest level of total phenolic contents (196.52± 10.76 µg GAE/mg Extract). These findings confirmed the remarkably antioxidant properties of this plant with DPPH scavenging activity and FRAP test. A concentration of 160 µg/ml of this extract showed a protective effect against hemolysis induced by AAPH radical. Hence, Zygophyllum album extracts demonstrated lower level of total phenolic contents (30.41 ± 2.01 µg GAE/mg Extract) and lower antioxidant and antihemolytic activities. Globularia alypum extracts presented a powerful antioxidant and antihemolytic activities especially for the decoction extract whereas Zygophyllum album revealed a weaker protective effect except its maceration extract.

show abstract

Polyphenol composition and antioxidant activity of Searsia tripartita and Limoniastrum guyonianum growing in Southeastern Algeria

Cited by 8 publications

References 45 publications

Phytochemical Screening and Antioxidant Potential of Selected Extracts from Betula alba var. pendula Roth., Glycyrrhiza glabra L., and Avena sativa L.

Phytochemical Screening and Antioxidant Potential of Selected Extracts from Betula alba var. pendula Roth., Glycyrrhiza glabra L., and Avena sativa L.

HPLC-DAD Screening and Antioxidant Activity of Phenolic Compounds of Salvia balansae de Noé Leaves Extract

Antihemolytic and antioxidant activities of aerial parts extracts of Zygophyllum album L. and Globularia alypum L. from Algeria

Contact Info

Product

Resources

About