Polyphenolic Composition, Antioxidant and Antibacterial Activities for Two Romanian Subspecies of Achillea distans Waldst. et Kit. ex Willd.

Benedec, Daniela; Vlase, Laurian; Oniga, Ilioara; Moţ, Augustin C.; Damian, Grigore; Hanganu, Daniela; Duma, Mihaela; Silaghi-Dumitrescu, Radu

doi:10.3390/molecules18088725

Cited by 73 publications

(108 citation statements)

References 28 publications

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“…distans (Asteraceae family) was assessed. [24] The work showed similar results of radical scavenging activity with TEAC values of 42.14 and 46.72 µmol Trolox/mg, respectively. Moreover, there are no previously data about the phenolic profile of O. africana certainly because of its position as endemic species.…”

Section: Antioxidant Activitysupporting

confidence: 68%

Chemical composition and bioactivities of the polyphenolic-rich extract of Ormenis africana Jord. and Fourr

Béjaoui

Boulila

Salem

et al. 2016

International Journal of Food Properties

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Ormenis africana is an endemic North African species used in folk medicine because of its hypoglycemic property. In this study, the α-amylase and α-glucosidase inhibition and antioxidant activities of the polyphenolic-rich extract from O. africana were determined. The chemical composition was made using liquid chromatography with photodiode array and electrospray ionization mass spectrometry method and the identification of phenolics was assessed by comparing their retention times and ultraviolet and mass spectra with those of the standards and/or reported in the literature. The total phenolic content was estimated by the Folin-Ciocalteu method. The antidiabetic potential was estimated by the determination of α-amylase and α-glucosidase inhibition in vitro. Four assays were used for the evaluation of antioxidant activity of the extracts. Seventeen phenolic compounds were detected. The major peaks are chlorogenic acid, 5-O-di-caffeoylquinic acid, and apigenin and luteolin derivatives. The polyphenolic-rich extract showed remarkable α-amylase and α-glucosidase inhibition activity in a concentration dependent manner. Furthermore, the extract also demonstrated high antioxidant activities. O. africana can serve as a potential natural source for the development of a novel α-amylase and α-glucosidase inhibitory agents against diabetic complications. ARTICLE HISTORY

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Section: Antioxidant Activitysupporting

confidence: 68%

Chemical composition and bioactivities of the polyphenolic-rich extract of Ormenis africana Jord. and Fourr

Béjaoui

Boulila

Salem

et al. 2016

International Journal of Food Properties

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“…2,2-Diphenyl-1-picrylhydrazyl (DPPH) radical scavenging is considered a good in vitro model, being widely used to conveniently assess antioxidant efficacy, as a rapid, easy, and cost-effective spectrophotometric method [34,35]. DPPH radicals are stable free radicals, which are neutralized in the presence of molecules capable of donating H atoms or electrons.…”

Section: Dpph Based Free Radical Scavenging Activitymentioning

confidence: 99%

New Hydrazones Bearing Thiazole Scaffold: Synthesis, Characterization, Antimicrobial, and Antioxidant Investigation

et al. 2015

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New series of hydrazones 5-18 were synthesized, in good yields, by reacting 4-methyl-2-(4-(trifluoromethyl)phenyl)thiazole-5-carbohydrazide with differently substituted benzaldehyde. The resulting compounds were characterized via elemental analysis, physico-chemical and spectral data. An antimicrobial screening was done, using Gram (+), Gram (−) bacteria and one fungal strain. Tested molecules displayed moderate-to-good growth inhibition activity. 2,2-Diphenyl-1-picrylhydrazide assay was used to test the antioxidant properties of the compounds. Monohydroxy (14-16), para-fluorine (13) and 2,4-dichlorine (17) derivatives exhibited better free-radical scavenging ability than the other investigated molecules.

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“…Due to the importance of plants in human health, it would be useful to know their contents on phenolic compounds and their biological activities (Benedec et al, ).…”

Section: Resultsmentioning

confidence: 99%

Comparison of phytochemicals, antimicrobial, and antioxidant capacities in different anatomical parts ofFicus microcarpa(Moraceae)

Rjeibi

Ncib

Alimi

et al. 2017

Journal of Food Biochemistry

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The aim of the present study was to compare the nutritional value, chemical composition, antioxidant capacity, and antimicrobial activity of leaves, fruits, and roots from Ficus microcarpa. The results showed that all plant parts are rich sources of sulfated polysaccharides and phenolics; in aerial roots, polyphenols and flavonoids dominate. Epicatechin, coumaric acid, and quercetin were present in roots, leaves, and fruits, but in different amounts. Gallic acid and rutin were detected only in roots extracts. The minerals compositions indicated that K, Na, Mn, Fe, Cu, and Zn were present in all plant parts. The antioxidant properties determined by hydrogen peroxide scavenging assays and 2,2‐diphenyl‐1‐picrylhydrazyl assays, and antimicrobial activity against Staphylococcus aureus, Micrococcus luteus, Escherichia coli, and Pseudomonas aeruginosa were better in root and in correlation with the chemical composition changes. Practical applications Our results provided evidence that the F. microcarpa could be a potential source of natural antioxidant that may replace synthetic product and prevents from oxidative stress induced by reactive oxygen species. Moreover, due to its potential antimicrobial activity, F. microcarpa can be used in pharmaceutical industry to treat damages caused by some pathogenic germs.

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Polyphenolic Composition, Antioxidant and Antibacterial Activities for Two Romanian Subspecies of Achillea distans Waldst. et Kit. ex Willd.

Cited by 73 publications

References 28 publications

Chemical composition and bioactivities of the polyphenolic-rich extract of Ormenis africana Jord. and Fourr

Chemical composition and bioactivities of the polyphenolic-rich extract of Ormenis africana Jord. and Fourr

New Hydrazones Bearing Thiazole Scaffold: Synthesis, Characterization, Antimicrobial, and Antioxidant Investigation

Comparison of phytochemicals, antimicrobial, and antioxidant capacities in different anatomical parts ofFicus microcarpa(Moraceae)

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