Polyphenolic compounds from the leaves of <i>Koelreuteria paniculata</i> Laxm

Lin, Wenhan; Deng, Zhiwei; Lei, Haiming; Fu, Hongzheng; Li, Jun

doi:10.1080/1028602021000049087

Cited by 31 publications

(23 citation statements)

References 13 publications

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“…The 2 C 28 H 24 O 15 isomers had analogous UV absorption peaks to compound 2, and had exactly 1 more gallic‐acid moiety, respectively; therefore, they are possibly gallic‐acid derivates from compound 2. Database searching with the molecular formulas and UV‐absorption peaks indicated that the 2 molecules were possibly 2″‐O‐Galloylquercitrin (compound 6) and 3″‐O‐Galloylquercitrin (compound 7) that were reported from medicinal plants Polygonum filiforme and Koelreuteria paniculata (Lin and others 2002). …”

Section: Resultsmentioning

confidence: 99%

Activity‐Guided Isolation and Identification of Radical Scavenging Components in Gao‐Cha Tea

Lu¹,

Hu²,

Xia³

2010

Journal of Food Science

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Gao-Cha is a traditional Chinese health tea made from Acer ginnala. We performed a components and radical scavenging activity analysis to identify any medicinal components in this tea. High performance thin layer chromatography (HPTLC)-1,1-Diphenyl-2-picryhydrazyl (HPTLC-DPPH) assay showed that the methanolic extract contained strong radical scavengers. Quantitative analysis revealed that the IC(50) of the extract against 1 mM DPPH was 52.7 ± 0.6 μg/mL. Bioactive-guided isolations led to procurement of 3 radical scavengers with IC(50)s of 17.5 ± 2.1, 29.3 ± 2.5, and 21.6 ± 1.7 μg/mL, respectively. Analysis of the high resolution-electric spray ionization-mass spectrometer and (1)H, (13)C, distortionless enhancement by polarization transfer at 135°, heteronuclear quantum coherence, correlating spectroscopy coupling, and heteronuclear multiple bond coherence (HMBC) data revealed that the compounds were methyl 3, 4, 5-trihydroxybenzoate (1), quercetin-3-O-α-rhamnopyranoside (2), and 2,6-bis (3,4,5-trihydroxybenzoyl)-aceritol (3). Bioactive combined components analysis revealed that, apart from compounds 1, 2, and 3, the tea possibly contained radical scavengers: ginnalin A (4) and B (5), 2″-O-Galloylquercitrin (6) and 3″-O-Galloyl-quercitrin (7). Compounds 2, 6, and 7 were isolated from Acer ginnala for the first time. The positions of the 2 galloyl moieties in compound 3 were unambiguously established by the HMBC spectrum for the first time.

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Section: Resultsmentioning

confidence: 99%

Activity‐Guided Isolation and Identification of Radical Scavenging Components in Gao‐Cha Tea

Lu¹,

Hu²,

Xia³

2010

Journal of Food Science

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“…30 (1H, dd, J = 1.6 Hz, H-6') showed o-coupled protons on ring B, while the signal at δ 7.35 (1H, d, J = 1.6 Hz, H-2') exhibited m-coupled, all of an ABC system, characteristic of 3', 4'-substituted ring B. (Bombardelli et al, 1973;Lin et al, 2002).…”

Section: Resultsmentioning

confidence: 99%

“…Bulked fraction C gave quercitrin which showed less antibacterial activity with the MIC value of 50 µg/ml. Quercitrin has been isolated from plants, such as Piliostigma thonningii (Ibewuike, 1997;Bombardelli et al, 1973), Koelreuteria paniculata (Lin et al, 2002) and Hypericum caprifoliatum (Dall et al, 2003), and its antimicrobial activity widely reported in such plants.…”

Section: Resultsmentioning

confidence: 99%

Antibacterial constituents of the leaves of Dacryodes edulis

Ajibesin¹,

Essien²,

Adesanya³

2011

Afr. J. Pharm. Pharmacol.

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Dacryodes edulis is a dioecious, small to medium-sized tree, reaching 20 to 25 m high. Different parts of the plant are used to treat many diseases including skin infections, digestive tract disorder and dysentery. The leaves were macerated in 50% ethanol and the liquid extract concentrated to dryness. The dry extract was evaluated for antibacterial activity by using agar diffusion method. The extract was partitioned between water, ethyl acetate and butanol successively and further subjected to antibacterial testing. The most active fraction, ethyl acetate fraction, was purified through various chromatographic methods to obtain pure compounds identified by spectroscopic methods as ethylgallate and quercitrin. These compounds gave good antibacterial effects, while the minimum inhibitory concentrations of the fractions and the pure compounds ranged between 12.5 and 250 µg/ml. These phenolic compounds are reported for the first time in this plant.

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“…Compounds 4-14 were identified by using 1 H NMR, 13 C NMR, DEPT-135, HMQC and HMBC as well as HRESIMS experiments, as: 5- O -methyl-luteolin 4 (Abou-Zaid et al, 2001), loliolide 5 (Kimura and Maki, 2002), kaempferol 7- O -α- l -rhamnoside 6 (Chua et al, 2008), kaempferol-3- O -α- l -rhamnoside (Afzelin) 7 (Cheng et al, 2013), methyl myo-inositol (Quebrachitol) 8 (HuiCong et al, 2013), β-sitosterol 9 (Lu et al, 2012), β-sitosterol-β- d -glucoside 10 (Wei et al, 2011), palmitic acid monoglyceride 11, ethyl gallate 12 (Yang et al, 1999), methyl gallate 13 (Lin et al, 2002) and gallic acid 14 (Qu et al, 2011). Compounds 4-6 were reported to be isolated for the first time from family Sapindaceae.…”

Section: Resultsmentioning

confidence: 99%

“…It is widely distributed in Northern China. Local people use the seeds as insecticides and the leaves as antifungal and antibacterial agents (Lin et al, 2002). Recent reports showed that the crude extracts of this plant possessed antitumor and antioxidant activities.…”

Section: Introductionmentioning

confidence: 99%

New triterpenoidal saponins from Koelreuteria paniculata

Mostafa

El‐Hela

Mohammad

et al. 2016

Phytochemistry Letters

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Bioassay guided fractionation and chemical investigation of the ethanolic extract of the aerial parts of Koelreuteria paniculata Laxm. (Sapindaceae), resulted in the isolation and identification of three new triterpenoid saponins 1–3 named Paniculatosoid A–C, along with eleven known compounds. The structures of the isolated compounds were elucidated using 1D and 2D NMR experiments, HRESIMS, and comparison with literature data. The occurrence of tridesmosidic saponin is reported for the first time from family Sapindaceae, as well as it is rarely found in natural saponins. Compounds 4–13 were evaluated for their antibacterial, antifungal, antimalarial and antileishmanial activities. Compound 12 showed weak antibacterial activity against Escherichia coli with an IC50 value of 101 μM. Compounds 12 and 13 showed antimalarial activity against chloroquine-sensitive (D6) Plasmodium falciparum protozoan with IC50 values of 6.46 and 6.95 μM, and against chloroquine-resistant (W2) Plasmodium falciparum protozoan with IC50 values of 9.34 and 4.18 μM.

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Polyphenolic compounds from the leaves of Koelreuteria paniculata Laxm

Cited by 31 publications

References 13 publications

Activity‐Guided Isolation and Identification of Radical Scavenging Components in Gao‐Cha Tea

Activity‐Guided Isolation and Identification of Radical Scavenging Components in Gao‐Cha Tea

Antibacterial constituents of the leaves of Dacryodes edulis

New triterpenoidal saponins from Koelreuteria paniculata

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