Polyphenolic profile and antioxidant properties of bee-collected pollen from sunflower (Helianthus annuus L.) plant

Kostić, Aleksandar Ž.; Milinčić, Danijel D.; Gašić, Uroš; Nedić, Nebojša; Stanojević, Sladjana P.; Tešić, Živoslav Lj.; Pešić, Mirjana B.

doi:10.1016/j.lwt.2019.06.011

Cited by 85 publications

(90 citation statements)

References 47 publications

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“…Extraction of extractable phenolic compounds was performed following the procedure proposed by Kostić et al (2019). Polyphenols were extracted by 80% methanol.…”

Section: Methodsmentioning

confidence: 99%

Polyphenolic profiles, antioxidant, and in vitro anticancer activities of the seeds of Puno and Titicaca quinoa cultivars

et al. 2020

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Background and objectives Quinoa is considered to be a “natural functional food” due to a lot of bioactive compounds that are beneficial for human health by helping prevent the risks of different diseases. The aim of this study was to test the health‐promoting characteristics of Puno and Titicaca quinoa seeds grown in Serbia by assessing their phenolic and flavonoid content, antioxidant activities, and potential anticancer effect on human colorectal cancer cells. Findings Thirteen phenolic compounds were identified and quantified in the seeds of both cultivars, but their profile and concentration of individual phenolic compounds differed. Cytotoxic activities were present in both cultivars, whereas the pronounced concentration and time‐dependent effects were more expressed in Puno extracts. Conclusions The extracts of the seeds of both cultivars are a rich source of phenolic and flavonoid compounds and with high antioxidant activities. Potent anticancer activity against the human colorectal cancer was expressed in both investigated cultivars. Significance and novelty The study confirmed the health benefit potential of Puno and Titicaca quinoa cultivars, grown in Serbia. These results are the first to demonstrate a potent anticancer activity of quinoa seed extract against the human colorectal cancer cell line HCT‐116, as well as the presence of 7 new phenolic and flavonoid compounds.

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“…Extraction of extractable phenolic compounds was performed following the procedure proposed by Kostić et al (2019). Polyphenols were extracted by 80% methanol.…”

Section: Methodsmentioning

confidence: 99%

Polyphenolic profiles, antioxidant, and in vitro anticancer activities of the seeds of Puno and Titicaca quinoa cultivars

et al. 2020

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“…floral pollen from Murcia University (USA) contains quercetin, kaempferol, and isorhamnetin and its derivates as the main phenolic compounds [13]. [15,151].…”

Section: Pollen As a Source Of Polyphenolsmentioning

confidence: 99%

“…The dominant presence and high content of carbohydrates, proteins, and lipids highlights pollen as an ideal natural supplement that provides energy; it has good nutritional value, regulates certain biochemical functions, and strengthens the body's immune and physiological systems [4,6]. Furthermore, pollen is a rich source of different important compounds ( Figure 1)-vitamins (with the prevalence of group-B vitamins) [7,8], carotenoids (such as lutein, β-cryptoxanthin, and β-caroten) [9], minerals [10][11][12], and polyphenols [13][14][15], which makes it attractive for use in the diets of children and adults suffering from certain avitaminoses and loss of appetite. Due to the diversity of active natural metabolites, especially vitamins, carotenoids, and polyphenols, pollen has a significant biological activity, expressed as the antioxidant, antibacterial, and anti-carcinogenic activity and the hepatoprotective, and the cardioprotective effect [6].…”

Section: Introductionmentioning

confidence: 99%

The Application of Pollen as a Functional Food and Feed Ingredient—The Present and Perspectives

et al. 2020

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Pollen is recognized as an excellent dietary supplement for human nutrition, which is why it can be found in different forms on the market (granules, capsules, tablets, pellets, and powders). But, the digestibility of pollen's nutrients is strongly affected by the presence of a pollen shell, which can decrease the bioavailability of nutrients by 50% and more. Since consumers have become more aware of the benefits of a healthy diet and the necessity to improve pollen digestibility, different pollen-based functional food products have been developed and extensive studies were done to estimate the beneficial effects of pollen-based feed on animal growth, health, and rigor mortise stage. Considering the positive effects of pollen nutrients and phytometabolites on human and animal health, the aim of this paper was to give an overview of recent achievements in the application of pollen in the formulation of functional food and animal diets. Special attention was paid to the effects of pollen's addition on the nutritional, functional, techno-functional, and sensory properties of the new formulated food products. Anti-nutritional properties of pollen were also discussed. This review points out the benefits of pollen addition to food and feed and the possible directions in the further development of functional food and feed for the wellbeing of everyone.Biomolecules 2020, 10, 84 2 of 36 improvement and for the prevention of some respiratory infections. In addition, they emphasized the fact of the longevity of some residents of Ukraine and Russia which can be linked to their regular consumption of honey enriched with pollen [2]. Since then, a significant "breakthrough" about the application of pollen as a dietary supplement has been made and the number of available research articles has drastically increased.Nowadays, pollen is often recognized as the "only perfectly complete food" [4], and "the world's best food product" [5]. The dominant presence and high content of carbohydrates, proteins, and lipids highlights pollen as an ideal natural supplement that provides energy; it has good nutritional value, regulates certain biochemical functions, and strengthens the body's immune and physiological systems [4,6]. Furthermore, pollen is a rich source of different important compounds (Figure 1)-vitamins (with the prevalence of group-B vitamins) [7,8], carotenoids (such as lutein, β-cryptoxanthin, and β-caroten) [9], minerals [10][11][12], and polyphenols [13][14][15], which makes it attractive for use in the diets of children and adults suffering from certain avitaminoses and loss of appetite.

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“…The presence of each identified peak (glycoside) from all bee-pollen samples is shown in Table S2 (Supplementary Material). Tentative identification of flavonol glycosides was done using the MS fragmentation data available in the literature [5][6][7][8]33]. The nature of interglycosidic linkages (1→2 or 1→6) for the identified flavonol glycosides was proposed according to Ferreres et al [11].…”

Section: Identification Of Flavonoid Glycosides By Uhplc-ltq Orbitrap Msmentioning

confidence: 99%

“…However, due to the high diversity of phenolic substances, quantitative determination of individual flavonoid glycosides is difficult. For example, liquid chromatography (LC) coupled with mass spectrometry (MS) has been applied in recent research for the identification and quantification of flavonol glycosides in bee-pollen [4][5][6][7][8], red spice paprika from Serbia [9], as well as in Lathyrus cicera L. seeds [10]. Using advanced LC-MS techniques, the structures of compounds, for which standards are not commercially available, could be determined by the study of their characteristic fragmentation patterns thanks to the great number of rules for structural characterization that were summarized in the past [11][12][13].…”

Section: Introductionmentioning

confidence: 99%

Phenolic Composition Influences the Health-Promoting Potential of Bee-Pollen

et al. 2019

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Information on compositional, nutritional and functional properties of bee-pollen, as a health-promoting food, is essential for defining its quality. Concerning the nutritional importance of phenolic compounds, the aim of this study was to determine the phenolic profile and antioxidant activity of twenty-four bee-pollen samples collected from different regions of Serbia. High-performance thin-layer chromatographic (HPTLC) fingerprinting was used for profiling of bee-pollen samples according to the botanical type. HPTLC hyphenated with image analysis and a pattern recognition technique confirmed the grouping of samples caused by the specific phenolic composition of pollens of different botanical origin. Flavonoid glycosides in bee-pollen samples were identified by applying ultra-high-performance liquid chromatography (UHPLC) coupled with linear ion trap-Orbitrap mass spectrometry (LTQ Orbitrap MS). Eight out of twenty-seven flavonol glycosides were identified in bee-pollen samples for the first time. All analyzed bee-pollen samples showed a high number of phenolic compounds which may have therapeutic potential.

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Polyphenolic profile and antioxidant properties of bee-collected pollen from sunflower (Helianthus annuus L.) plant

Cited by 85 publications

References 47 publications

Polyphenolic profiles, antioxidant, and in vitro anticancer activities of the seeds of Puno and Titicaca quinoa cultivars

Polyphenolic profiles, antioxidant, and in vitro anticancer activities of the seeds of Puno and Titicaca quinoa cultivars

The Application of Pollen as a Functional Food and Feed Ingredient—The Present and Perspectives

Phenolic Composition Influences the Health-Promoting Potential of Bee-Pollen

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