Polypoidal choroidal vasculopathy masquerading as central serous chorioretinopathy

Yannuzzi, Lawrence A.; Freund, K. Bailey; Goldbaum, Mauro; Scassellati-Sforzolini, Baldo; Guyer, David R.; Spaide, Richard F.; Maberley, David; Wong, Damon Wing Kee; Slakter, Jason S.; Sorenson, John A.; Fisher, Yale L.; Orlock, Dennis A.

doi:10.1016/s0161-6420(99)00173-6

Cited by 188 publications

(101 citation statements)

References 22 publications

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“…A history of CSC implied CSC in either eye because there was often a bilateral pathology in the choroidal vasculature even with a unilateral clinical presentation. 24,25,27,28 Because PCV masquerading as CSC 21 was a well-known phenomenon, we had to confirm the reported history of CSC and that these incidences were not actually PCV or exudative AMD. Therefore, in this study, we excluded two reports on the history of CSC that supposedly occurred after the age of 50 years and within 10 years of the onset of AMD.…”

Section: Discussionmentioning

confidence: 99%

Polypoidal choroidal vasculopathy and history of central serous chorioretinopathy

Toyama

Ohtomo

Noda

et al. 2014

Eye

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Purpose To evaluate the possible causative role of central serous chorioretinopathy (CSC) in the development of exudative age-related macular degeneration (AMD). Methods In a cross-sectional study at an institutional setting, 150 control subjects who had senile cataract or nasolacrimal duct stenosis and who were older than 50 years were enrolled. The background data for 89 patients with typical AMD (tAMD) and 138 patients with polypoidal choroidal vasculopathy (PCV) were used for comparison. Their medical records were taken for history of CSC, hypertension, systemic steroid use, and smoking. The fundus was also evaluated for signs of atrophic retinal pigment epithelial (RPE) tract and for focal photocoagulation scars in the macula. Results After adjusting for age, gender, and history of hypertension, systemic steroid use, and smoking, history of CSC was significantly more frequent (Po0.0001) in patients with PCV (15 patients, 10.9%) compared with patients with tAMD (2 patients, 2.2%) or control subjects (0 patients). On fundoscopy, an atrophic RPE tract (seven patients) or a focal photocoagulation scar (one patient) was observed only in patients with PCV (eight patients, 5.8%), and the frequency was statistically significant compared with that with tAMD (P ¼ 0.0143) or control subjects (P ¼ 0.0143). The laterality of CSC and AMD involved the same eye in 9 of 10 patients among those who had unilateral AMD and a reported unilateral CSC history. Conclusion A history of CSC may be a predisposing factor for the development of PCV in the Japanese population.

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Section: Discussionmentioning

confidence: 99%

Polypoidal choroidal vasculopathy and history of central serous chorioretinopathy

Toyama

Ohtomo

Noda

et al. 2014

Eye

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“…Vascular diseases include malignant hypertension, toxemia of pregnancy, retinal vein occlusion, Coats disease, retinal angiomatous diseases, and different forms of choroidal neovascularization including polypoidal choroidal vasculopathy. 53,54 Choroidal tumors that may be associated with SRD include some nevi, melanoma, hemangioma, lymphoma, and metastatic tumors. Other conditions that are associated with SRD include central serous chorioretinopathy, familial exudative vitreoretinopathy, Norrie disease, uveal effusion syndrome, nanophthalmia, and optic nerve head pits and colobomas are still somewhat enigmatic and are not classified under any of the three disease processes that lead to SRD discussed above.…”

Section: (Iii) Types and Pathogenetic Mechanisms Of Retinal Detachmentmentioning

confidence: 99%

Pathology and pathogenesis of retinal detachment

Ghazi

Green

2002

Eye

227

160

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Retinal detachment, separation of the neurosensory retina from the underlying retinal pigment epithelium, is a sight threatening condition that is considered one of the few ocular emergencies. The literature is enormously rich in studies that focused on different aspects of this disease process. Yet certain aspects remain largely unanswered. We briefly review major aspects of retinal detachment and discuss various important contributions in this field, focussing mainly on the pathogenesis of and predisposing factors to retinal detachment, and on the pathologic changes that occur following its development and following various surgical procedures currently used in its management.

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“…Nos casos resistentes ao tratamento, sugere-se a investigação diagnóstica de prová-veis pontos de escape situados fora do pólo posterior e doenças que podem simular quadros de CCS conforme citadas no diagnóstico diferencial, principalmente membranas neovasculares de coróide e coroidopatia vascular polipoidal (36) . Os riscos da fotocoagulação na região justa-foveal são consideráveis.…”

Section: Tratamentounclassified

Coroidoretinopatia central serosa

Serracarbassa¹

2002

Arq. Bras. Oftalmol.

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O autor descreve os achados clínicos e novos métodos diagnósticos da coroidoretinopatia central serosa. Discute os estudos experimentais e clínicos relacionados à patogênese da doença e apresenta as alternativas de tratamento e prognóstico da coroidoretinopatia central serosa, baseado em levantamento bibliográfico. Os aspectos clínicos da coroidoretinopatia central serosa (CCS) foram inicialmente descritos por Von Graefe* em 1886 (1) . Cerca de cem anos depois, Maumenee (2) , utilizando-se da angiofluoresceinografia, observou que o descolamento seroso da retina na região macular era conseqüência do escape de contraste no epitélio pigmentado da retina (EPR). INCIDÊNCIAA CCS atinge preferencialmente indivíduos do sexo masculino (em 85% dos casos), na faixa etária de 20 a 45 anos. É rara em pacientes da raça negra, e pode apresentar formas atípicas quando atinge indivíduos de origem latina e oriental.Pacientes com personalidade descrita como "perfil tipo A", caracterizados por altos níveis de tensão emocional e ansiedade, apresentariam predisposição para o desenvolvimento da CCS.A doença é tipicamente unilateral, podendo acometer o olho adelfo em 10% dos casos de forma simultânea ou intercalada. Apesar da unilateralidade, são observadas alterações atróficas do EPR nos olhos contra-laterais em cerca de 1/3 dos pacientes.

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Polypoidal choroidal vasculopathy masquerading as central serous chorioretinopathy

Cited by 188 publications

References 22 publications

Polypoidal choroidal vasculopathy and history of central serous chorioretinopathy

Polypoidal choroidal vasculopathy and history of central serous chorioretinopathy

Pathology and pathogenesis of retinal detachment

Coroidoretinopatia central serosa

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