Polyposis Syndromes

and, Randall W. Burt; Jasperson, Kory

doi:10.1002/9781118512074.ch79

Yamada' S Textbook of Gastroenterology 2015

DOI: 10.1002/9781118512074.ch79

|View full text |Cite

Polyposis Syndromes

Randall W. Burt and

Kory Jasperson

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2020

Publication Types

Select...

Book1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 346 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Cancers of the gastrointestinal tract

Labib¹,

Bridgewater²,

Pereira³

2020

Oxford Textbook of Medicine

View full text Add to dashboard Cite

Cancers of the gastrointestinal tract are one of the most rewarding interfaces in translational medicine, leading to greater understanding of the genetic mechanisms leading to cancer and the development of novel targeted therapies. Diagnosis of gastrointestinal tract cancers is usually made or suspected at endoscopy and confirmed by biopsy. Oesophageal cancer is a common cancer, usually of squamous cell histology, that is particularly prevalent in East Asia and Southeast Africa. Typical presentation is with dysphagia. Overall survival at 5 years is 15%. Usually adenocarcinoma, stomach cancer is particularly prevalent in East Asia, Eastern Europe, and Western South America. Predisposing factors include Helicobacter pylori infection, low socioeconomic status, tobacco smoking, heavy alcohol use, and diet. Dysphagia, early satiety, and anaemia are common presenting features, with weight loss being an indication of advanced disease. Overall survival at 5 years is 18.9%. Colorectal cancer is the third most common cancer in men and second most common in women worldwide, and is predisposed to by a Western diet. Most cases arise by transformation of an adenoma to a carcinoma by sequential inherited and acquired mutations. Typical presentations of left-sided tumours are alteration in bowel habit, obstruction, or overt bleeding, whereas right-sided tumours often present with iron-deficiency anaemia. Overall survival at 5 years is now almost 60%.

show abstract

Cancers of the gastrointestinal tract

Labib¹,

Bridgewater²,

Pereira³

2020

Oxford Textbook of Medicine

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Polyposis Syndromes

Cited by 1 publication

References 346 publications

Cancers of the gastrointestinal tract

Cancers of the gastrointestinal tract

Contact Info

Product

Resources

About