Polysaccharide-Based Graft Copolymers for Biomedical Applications

Pal, Sagar; Das, Ranajit

doi:10.1007/978-3-642-36566-9_9

Cited by 4 publications

(4 citation statements)

References 103 publications

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“…Resveratrol exhibits comparable antioxidant activity as quercetin, polyphenols, Vitamin C, and E, phenolic compounds, carotenoids, α-lipoic acid, melatonin, gallic acid, and N-acetyl cysteine, captopril. However, the material is superior to other antioxidants based on its broad biological activity, including anticancer, anti-inflammatory and chemoprevention properties, and rapid metabolism within the body due to its shortened half-life [104]. The mechanical, biological, and chemical properties can be enhanced through modifications in the synthetic routes.…”

Section: Resveratrol Conjugated and Grafted Polymersmentioning

confidence: 99%

“…The mechanical, biological, and chemical properties can be enhanced through modifications in the synthetic routes. For example, Siddalingappa et al [104] reported the successful synthesis of Resveratrol-PEG ethers via alkali-mediated etherification. The plasma stability of the moieties was augmented by aggregation behavior and polymer hydrophobicity, and the antioxidant demonstrated ideal antioxidant behavior in mice models.…”

Section: Resveratrol Conjugated and Grafted Polymersmentioning

confidence: 99%

“…The plasma stability of the moieties was augmented by aggregation behavior and polymer hydrophobicity, and the antioxidant demonstrated ideal antioxidant behavior in mice models. Further customized changes were viable through carbodiimide coupling reaction-mediated surface and chemical modifications with α-methoxy poly (ethylene glycol)-co-polylactide succinyl ester resveratrol, MeO-PEG succinyl ester resveratrol, and α-methoxy-ω-carboxylic acid poly(ethylene glycol) succinylamide resveratrol [104].…”

Section: Resveratrol Conjugated and Grafted Polymersmentioning

confidence: 99%

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Recent Advances in Antioxidant Polymers: From Sustainable and Natural Monomers to Synthesis and Applications

2021

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Advances in technology have led to the production of sustainable antioxidants and natural monomers for food packaging and targeted drug delivery applications. Of particular importance is the synthesis of lignin polymers, and graft polymers, dopamine, and polydopamine, inulin, quercetin, limonene, and vitamins, due to their free radical scavenging ability, chemical potency, ideal functional groups for polymerization, abundance in the natural environment, ease of production, and activation of biological mechanisms such as the inhibition of the cellular activation of various signaling pathways, including NF-κB and MAPK. The radical oxygen species are responsible for oxidative damage and increased susceptibility to cancer, cardiovascular, degenerative musculoskeletal, and neurodegenerative conditions and diabetes; such biological mechanisms are inhibited by both synthetic and naturally occurring antioxidants. The orientation of macromolecules in the presence of the plasticizing agent increases the suitability of quercetin in food packaging, while the commercial viability of terpenes in the replacement of existing non-renewable polymers is reinforced by the recyclability of the precursors (thyme, cannabis, and lemon, orange, mandarin) and marginal ecological effect and antioxidant properties. Emerging antioxidant nanoparticle polymers have a broad range of applications in tumor-targeted drug delivery, food fortification, biodegradation of synthetic polymers, and antimicrobial treatment and corrosion inhibition. The aim of the review is to present state-of-the-art polymers with intrinsic antioxidant properties, including synthesis scavenging activity, potential applications, and future directions. This review is distinct from other works given that it integrates different advances in antioxidant polymer synthesis and applications such as inulin, quercetin polymers, their conjugates, antioxidant-graft-polysaccharides, and polymerization vitamins and essential oils. One of the most comprehensive reviews of antioxidant polymers was published by Cirillo and Iemma in 2012. Since then, significant progress has been made in improving the synthesis, techniques, properties, and applications. The review builds upon existing research by presenting new findings that were excluded from previous reviews.

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Section: Resveratrol Conjugated and Grafted Polymersmentioning

confidence: 99%

Section: Resveratrol Conjugated and Grafted Polymersmentioning

confidence: 99%

Section: Resveratrol Conjugated and Grafted Polymersmentioning

confidence: 99%

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Recent Advances in Antioxidant Polymers: From Sustainable and Natural Monomers to Synthesis and Applications

2021

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“…Natural polysaccharides can be modified through graft copolymerization with various monomers onto their chains by covalent bonds to improve their characteristic properties such as water repellency, thermal stability, acid-base, and flame resistance, and dyeability. Modified natural polysaccharides are widely used in potentially new applications because they have the advantages of natural polysaccharides in addition to synthetic polymers [1,52,61].…”

Section: Graft Copolymerization Of Xgmentioning

confidence: 99%

Synthesis and Potential Applications of Modified Xanthan Gum

Elella

2021

J. Chem. Eng. Res. Updates.

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Designing high-performance adsorbents for wastewater treatment and antibacterial materials for food and biomedical applications and excellent drug carrier to prolong time retention of the therapeutic drug based on biodegradable polymers has gained more interest in recent years. Among these materials, xanthan gum, which is a natural polysaccharide and plays a vital role in various applications such as industry, enhanced oil recovery, water-based paints, pharmaceuticals, and personal care products because it has excellent properties such as biodegradability and non-toxicity. On the other hand, it has many affected limitations, including microbially attack, poor thermal and mechanical stability, and low surface area. So, in this review, we focused on the advanced modifications on xanthan gum and their applications in wastewater treatment, protein delivery, and designing antimicrobial materials.

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Gum acacia polysaccharide-based pH sensitive gels for targeted delivery of neridronate

Aderibigbe

Ray

2016

Polym. Bull.

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Polysaccharide-Based Graft Copolymers for Biomedical Applications

Cited by 4 publications

References 103 publications

Recent Advances in Antioxidant Polymers: From Sustainable and Natural Monomers to Synthesis and Applications

Recent Advances in Antioxidant Polymers: From Sustainable and Natural Monomers to Synthesis and Applications

Synthesis and Potential Applications of Modified Xanthan Gum

Gum acacia polysaccharide-based pH sensitive gels for targeted delivery of neridronate

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