Polysaccharides in Sipunculus nudus: Extraction condition optimization and antioxidant activities

Zhang, Qin; Dong, Lanfang; Tong, Tong; Wang, Qingchao; Xu, Mingzhu

doi:10.1007/s11802-017-2969-5

Cited by 5 publications

(4 citation statements)

References 24 publications

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“…Sipunculus nudus polysaccharide (SNP) prepared by alkali extraction not only has strong hydroxyl and superoxide scavenging ability, but also inhibits the hematopoietic bone marrow damage induced by radiation via reducing the nitric oxide levels and increasing the activity of antioxidant enzymes [103,140]. Similarly, SNPs with an average molecular weight of 680 kDa prepared by alkali extraction not only have strong scavenging activity against hydroxyl radicals (99% at 10 mg/mL), but also prevent radiation-induced bone marrow oxidative damage by increasing DNA content in bone marrow cells (Tables 1 and 2) [104].…”

Section: Animal Polysaccharidesmentioning

confidence: 99%

The Antioxidant Activity of Polysaccharides Derived from Marine Organisms: An Overview

et al. 2019

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Marine-derived antioxidant polysaccharides have aroused extensive attention because of their potential nutritional and therapeutic benefits. However, the comprehensive comparison of identified marine-derived antioxidant polysaccharides is still inaccessible, which would facilitate the discovery of more efficient antioxidants from marine organisms. Thus, this review summarizes the sources, chemical composition, structural characteristics, and antioxidant capacity of marine antioxidant polysaccharides, as well as their protective in vivo effects mediated by antioxidative stress reported in the last few years (2013–2019), and especially highlights the dominant role of marine algae as antioxidant polysaccharide source. In addition, the relationships between the chemical composition and structural characteristics of marine antioxidant polysaccharides with their antioxidant capacity were also discussed. The antioxidant activity was found to be determined by multiple factors, including molecular weight, monosaccharide composition, sulfate position and its degree.

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Section: Animal Polysaccharidesmentioning

confidence: 99%

The Antioxidant Activity of Polysaccharides Derived from Marine Organisms: An Overview

et al. 2019

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“…Amino acid composition has an important effect on the antioxidant activity of peptides (Umayaparvathi et al, 2015). Previous reports show that the presence of hydrophobic amino acid residues is essential for antioxidant peptides (Shi et al, 2017 antioxidant activity (Zhang et al, 2017). Moreover, we showed that F5 (YAKRCFR) possessed the highest antioxidant activity.…”

Section: Discussionmentioning

confidence: 58%

“…In the present study, F1 through F5 were collected by RPLC due to different polarities, with their respective sequences (the highest‐abundance ion peak) identified as AWVDY, MSFRFY, EPLRY, RKPPWPP, and YAKRCFR. All peptides were abundant in hydrophobic amino acids, including Y residues present in the N‐terminus, which were previously reported as being involved in antioxidant activity (Zhang et al, 2017 ). Moreover, we showed that F5 (YAKRCFR) possessed the highest antioxidant activity.…”

Section: Discussionmentioning

confidence: 77%

“…The effect of hydroxyl radicals was measured using the 2‐deoxyribose oxidation method (Zhang et al, 2017 ). The reaction mixture contained 0.2 ml of 0.15 M sodium phosphate buffer (pH 7.4), 0.3 ml of 5 mM phenanthroline dissolved in ethanol, 0.3 ml of 0.75 mM FeSO 4 , 0.20 ml of 10 mM hydrogen peroxide, 1 ml of distilled water, and 1 ml of sample solutions in a tube.…”

Section: Methodsmentioning

confidence: 99%

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Isolation and characterization of antioxidant peptides from oyster (Crassostrea rivularis) protein enzymatic hydrolysates

Huang

Jianwei

Yang

et al. 2022

Food Science & Nutrition

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Peptides from oysters have several bioactive functions. In this study, we identified antioxidant peptides from oysters (Crassostrea rivularis) and investigated their structure–function relationship. We used an 8 kDa molecular‐weight (MW) cut‐off membrane and semiprep reversed‐phase liquid chromatography to collect five peptides (F1–F5) and identified the highest‐abundance ion‐peak sequences AWVDY (F1), MSFRFY(F2), EPLRY(F3), RKPPWPP(F4), and YAKRCFR(F5) having MWs of 652, 850, 676, 877, and 943 Da, respectively, using ultra‐performance liquid chromatography‐quadrupole/time‐of‐flight tandem mass spectrometry. These peptides exhibited high antioxidant activities, similar to butylated hydroxytoluene, reduced glutathione, and ascorbic acid. F5 demonstrated the highest scavenging activity for DPPH radicals (IC50 = 21.75 μg/ml), hydroxyl radicals (IC50 = 18.75 μg/ml), and superoxide radicals (IC50 = 11.00 μg/ml), while F3 demonstrated the highest reducing power. Furthermore, F5 significantly protected Caco‐2 cells from H2O2‐induced oxidative damage. These results suggest that the antioxidant peptide F5 is a promising food additive that protects against oxidative damage.

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Marine polymers and their antioxidative perspective

Sasidharan¹,

Sabu²,

Venugopal³

2023

Marine Antioxidants

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Polysaccharides in Sipunculus nudus: Extraction condition optimization and antioxidant activities

Cited by 5 publications

References 24 publications

The Antioxidant Activity of Polysaccharides Derived from Marine Organisms: An Overview

The Antioxidant Activity of Polysaccharides Derived from Marine Organisms: An Overview

Isolation and characterization of antioxidant peptides from oyster (Crassostrea rivularis) protein enzymatic hydrolysates

Marine polymers and their antioxidative perspective

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