Polyurethane foam covering for wounds, burns and ulcers

Smirnov, Sergey V.; Шахламов, М. В.; Litinsky, M.A.; Yanshin, D.V.; Sachkov, A. V.; Obolensky, V. N.

doi:10.1016/j.wndm.2013.10.001

Cited by 4 publications

(2 citation statements)

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“…The important development occurred during the 19th century due to the introduction of antibiotics. The modern wound dressing was established; the current approach for wound dressing is based on foams [ 7 ], films [ 8 ], hydrogel [ 9 ], and nanofibrous mats [ 10 ], with natural polymers such as alginate, chitosan, and bacterial cellulose or synthetic polymers such as polyurethane.…”

Section: Introductionmentioning

confidence: 99%

Cotton Cellulose-Derived Hydrogel and Electrospun Fiber as Alternative Material for Wound Dressing Application

Jirawitchalert

Mitaim

Chen

et al. 2022

International Journal of Biomaterials

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Cotton has been recognized as a useful biomaterial over decades, and it has been widely applied in the textile industry. However, a large amount of cotton waste is generated during the manufacturing processes, but it has been considered as a low-value product. With high content of cellulose remaining in cotton waste, our study focuses on transforming cotton cellulose into a valuable product. Cellulose was extracted from cotton waste and modified into two main materials for wound dressing application: hydrogel-based water absorbent materials and electrospun composite nanofibers. In order to enhance the water absorption, carboxymethyl cellulose (CMC), the modified cellulose with functional group prone to interact with water molecules, has been developed in this study. The hydrogel-based CMC was created by using the chemical cross-linking reaction of epichlorohydrin (ECH). The hydrogel demonstrated the swelling and reswelling ability by 1718 ± 137% and 97.95 ± 9.76%, respectively. Meanwhile, cellulose/PEG in trifluoroacetic acid (TFA) was successfully fabricated as nonwoven composite by a conventional electrospinning technique. The fabrics provided highly appropriated properties as wound dressing, including the following: water absorption was up to 1300 times and water vapor permeability controlled in the range of 2163–2285 g·m−2·day−1. This showed the preliminary information for recovering cotton waste into valuable products.

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Section: Introductionmentioning

confidence: 99%

Cotton Cellulose-Derived Hydrogel and Electrospun Fiber as Alternative Material for Wound Dressing Application

Jirawitchalert

Mitaim

Chen

et al. 2022

International Journal of Biomaterials

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show abstract

“…The selection of the material to be used is made according to its properties and the type of wound. In this respect, several materials can be used, such as hydrocolloids [8,9], foams [10], films [11,12] or hydrogels [1,[13][14][15].…”

Section: Introductionmentioning

confidence: 99%

Gelatin-PVP Hydrogels with Potential Skin Grafts Applications

Serafim

Petre

Moraru

et al. 2015

KEM

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This work presents the synthesis and characterization of natural-synthetic hydrogels based on gelatin (Gel) and polyvinylpyrrolidone (PVP), with potential for skin grafts applications. The natural component, Gel insures the biocompatibility and biodegradability of the bicomponent system [1], while the synthetic counterpart, PVP, is a physiologic inert component, extensively used in medicine due to its water affinity and due to its capacity of confer elasticity to films and membranes with potential applications in skin grafts [2]. The obtained hydrogels were subjected to morpho-structural analysis and rheological and mechanical tests (traction). The water affinity of the systems was estimated and their capacity to generate porous substrates through freeze-drying was evaluated.

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Development and Research of Polyurethane Foam Composite Materials With Lysozyme

Rudenchyk¹,

Rozhnova²,

Galatenko³

2021

Polim. z.

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The article is devoted to the development and research of the structure and properties of polyurethane foam (PUF) composite materials with the antibacterial enzyme lysozyme. A series of PUF composite materials with lysozyme of various concentrations (1, 3 and 5 wt %) were obtained. It is established that the immobilization of lysozyme occurs due to intermolecular hydrogen bonds by the method of IR spectroscopy. According to the results of physical-mechanical tests the adhesive strength of polyurethane foam compositions with lysozyme is in the range of 0,82–1,16 MPa. The introduction of lysozyme into the composition of polyurethane foams and an increase its amount causes a decrease in the values of adhesion strength by 18,1–29,3 %. According to differential scanning calorimetry the tested systems are single-phase with a glass transition temperature in the range of -49,20 to -49,86 °C. The introduction of lysozyme into the composition causes an increase heating capacity at the glass transition, which can be associated with a decrease of the packing density of macrochains resulting in an increase in free volume, which leads to an increase molecular mobility. According to the results of the analysis of transmission optical microscopy micrographs the studied PUF have a microporous structure, which depends on the content of filler in their composition. It was found that the presence of lysozyme in the composition of composite materials leads to a decrease in the percentage of porosity, an increase in the number of pores with a diameter of up to 300 μm, which is 76,7–82,4 % (while for PUF – 69,5 %) and the absence of pores with a diameter larger than 990 μm. Thermogravimetric characteristics indicate the heat resistance of the synthesized PUF to a temperature of 179,95 °C, which allows dry sterilization of samples without changing their characteristics. PUF composite materials with lysozyme are promising materials that can be used in medical practice as polymer compositions for the treatment of wounds and burns.

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Polyurethane foam covering for wounds, burns and ulcers

Cited by 4 publications

References 0 publications

Cotton Cellulose-Derived Hydrogel and Electrospun Fiber as Alternative Material for Wound Dressing Application

Cotton Cellulose-Derived Hydrogel and Electrospun Fiber as Alternative Material for Wound Dressing Application

Gelatin-PVP Hydrogels with Potential Skin Grafts Applications

Development and Research of Polyurethane Foam Composite Materials With Lysozyme

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