Polyvinyl Alcohol-based Hydrogel: A Systematic Literature Review on Thermal Properties by Differential Scanning Calorimetry

Putro, Permono Adi; Sulaeman, Ahmad Sofyan; Maddu, Akhiruddin

doi:10.1088/1742-6596/2019/1/012101

Cited by 5 publications

(2 citation statements)

References 82 publications

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“…BNPs-PT displayed three thermal events related to interactions between the polymers PVA and PLGA at 45.5, 56.6, and 94.89 °C. The first peak exhibited two signals at 45.5 and 56.6 °C, close to the typical endothermic peaks of PLGA and PVA’s glass transition [ 61 ]. The third peak at 94.89 °C may be related to trehalose’s crystalline nature.…”

Section: Resultsmentioning

confidence: 99%

PEG 400:Trehalose Coating Enhances Curcumin-Loaded PLGA Nanoparticle Internalization in Neuronal Cells

et al. 2023

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This work proposes a combination of polyethylene glycol 400 (PEG) and trehalose as a surface modification approach to enhance PLGA-based nanoparticles as a drug carrier for neurons. PEG improves nanoparticles’ hydrophilicity, and trehalose enhances the nanoparticle’s cellular internalization by inducing a more auspicious microenvironment based on inhibiting cell surface receptor denaturation. To optimize the nanoprecipitation process, a central composite design was performed; nanoparticles were adsorbed with PEG and trehalose. PLGA nanoparticles with diameters smaller than 200 nm were produced, and the coating process did not considerably increase their size. Nanoparticles entrapped curcumin, and their release profile was determined. The nanoparticles presented a curcumin entrapment efficiency of over 40%, and coated nanoparticles reached 60% of curcumin release in two weeks. MTT tests and curcumin fluorescence, with confocal imaging, were used to assess nanoparticle cytotoxicity and cell internalization in SH-SY5Y cells. Free curcumin 80 µM depleted the cell survival to 13% at 72 h. Contrariwise, PEG:Trehalose-coated curcumin-loaded and non-loaded nanoparticles preserved cell survival at 76% and 79% under the same conditions, respectively. Cells incubated with 100 µM curcumin or curcumin nanoparticles for 1 h exhibited 13.4% and 14.84% of curcumin’s fluorescence, respectively. Moreover, cells exposed to 100 µM curcumin in PEG:Trehalose-coated nanoparticles for 1 h presented 28% fluorescence. In conclusion, PEG:Trehalose-adsorbed nanoparticles smaller than 200 nm exhibited suitable neural cytotoxicity and increased cell internalization proficiency.

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Section: Resultsmentioning

confidence: 99%

PEG 400:Trehalose Coating Enhances Curcumin-Loaded PLGA Nanoparticle Internalization in Neuronal Cells

et al. 2023

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“…Based on the search and knowledge of the author, the study of the TP of PAA-based hydrogels using SLR has never been done before. In addition, the Boolean algorithm has been used in database search using Publish or Perish (PoP) software as a new strategy for SLR studies 40 , which gives very good results when using Google Scholar as the data source because it has a maximum limit of 1000 meta-databases. Therefore, this research can provide consideration for researchers among academics or practitioners in the synthesis of materials, especially poly(acrylic acid)–based hydrogels and their copolymerized forms.…”

Section: Introductionmentioning

confidence: 99%

Thermal studies of hydrogels based on poly(acrylic acid) and its copolymers by differential scanning calorimetry: A systematic literature review

Sulaeman

Putro

Nikmatin

2022

Polymers and Polymer Composites

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This systematic literature review aims to study the thermal properties (TP) of poly(acrylic acid)-based hydrogels (PAA) by differential scanning calorimetry. The data sources were obtained from Google Scholar via Publish or Perish software from 2018 to 2020. The synthesis results show that most of the analysis of TP in PAA-based hydrogel consists of glass transition temperature ([Formula: see text]), melting temperature ([Formula: see text]), and enthalpy ([Formula: see text]). The subsequent thermal properties analysis is important for a new development and depth study in the future application.

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Synthesis of silk sericin/silk fibroin/Moringa oleifera-based hydrogel with antibacterial activity

Hidayat,

Hardiansyah,

Kusuma Wardhani

et al. 2025

Biocatalysis and Agricultural Biotechnology

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Polyvinyl Alcohol-based Hydrogel: A Systematic Literature Review on Thermal Properties by Differential Scanning Calorimetry

Cited by 5 publications

References 82 publications

PEG 400:Trehalose Coating Enhances Curcumin-Loaded PLGA Nanoparticle Internalization in Neuronal Cells

PEG 400:Trehalose Coating Enhances Curcumin-Loaded PLGA Nanoparticle Internalization in Neuronal Cells

Thermal studies of hydrogels based on poly(acrylic acid) and its copolymers by differential scanning calorimetry: A systematic literature review

Synthesis of silk sericin/silk fibroin/Moringa oleifera-based hydrogel with antibacterial activity

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