In this paper, we propose a novel methodology that combines the opposition Nelder–Mead algorithm and the selection phase of the genetic algorithm. This integration aims to enhance the performance of the overall algorithm. To evaluate the effectiveness of our methodology, we conducted a comprehensive comparative study involving 11 state-of-the-art algorithms renowned for their exceptional performance in the 2022 IEEE Congress on Evolutionary Computation (CEC 2022). Following rigorous analysis, which included a Friedman test and subsequent Dunn’s post hoc test, our algorithm demonstrated outstanding performance. In fact, our methodology exhibited equal or superior performance compared to the other algorithms in the majority of cases examined. These results highlight the effectiveness and competitiveness of our proposed approach, showcasing its potential to achieve state-of-the-art performance in solving optimization problems.