Abstract:Objectives To assess the effectiveness of tecovirimat (TPOXX) for treating mpox in terms of difference in healing time and extent of viral clearance. Design Emulation of a target trial based on observational data. Setting Italy Participants Forty-one men hospitalized for mpox as of September 29th, 2022. Main outcome measures Main outcome was the time to clinical recovery. Secondary outcome was the variation in viral load in the upper respiratory tract (URT) after treatment. Results The median time from symptom… Show more
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