Poor oral Hygiene may be the Sole Cause of Oral Cancer

Oji, Chima; Chukwuneke, FN

doi:10.1007/s12663-012-0359-5

Cited by 34 publications

(28 citation statements)

References 21 publications

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“…Tooth loss is also related to poorer oral hygiene (Adegboye et al 2012 ; Marshall et al 2002 ). Poorer oral hygiene potentially affects the gastrointestinal flora and nutritional status and may thus have implications for the development of cancer (Huang et al 2016 ; Oji and Chukwuneke 2012 ).…”

Section: Discussionmentioning

confidence: 99%

Association between tooth loss and risk of oesophageal cancer: a dose–response meta-analysis

Wang

Peng

et al. 2016

SpringerPlus

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Many epidemiological studies have found that tooth loss is associated with susceptibility to oesophageal cancer. However, a definitive answer is yet to be discovered, and the findings are inconclusive. We performed a meta-analysis to assess the relationship between tooth loss and oesophageal cancer risk. We searched PubMed and Embase databases to screen eligible studies up to June 2015. Nine observational studies (eight articles) involving 2604 patients and 113,995 participants were included in the meta-analysis. The combined odds ratio for tooth loss and oesophageal cancer was 1.53 (95 % CI 1.02–2.29) for the high versus lowest teeth loss categories. However, inconsistent results were detected in the stratified and sensitivity analysis. In dose–response analysis, the summary odds ratio for each one tooth loss increment was 1.01 (95 % CI 1.00–1.02). The current evidence, based solely on six case–control studies and three cohort studies, suggests that tooth loss is a potential marker of oesophageal cancer. However, no firm conclusion can be drawn at this time that tooth loss may play a causal role in development of oesophageal cancer. Additional large-scale and high-quality prospective studies are required to evaluate the association between tooth loss and risk of oesophageal cancer.

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Section: Discussionmentioning

confidence: 99%

Association between tooth loss and risk of oesophageal cancer: a dose–response meta-analysis

Wang

Peng

et al. 2016

SpringerPlus

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“…74 Oral cancer is more likely to be associated with poor oral hygiene. 75,76 Moreover, there has been no effect on the breath alcohol levels after using the alcohol-containing mouthwash. 77…”

Section: Other Concernsmentioning

confidence: 99%

Translating mouthwash use for gonorrhoea prevention into a public health campaign: identifying current knowledge and research gaps

et al. 2019

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The gonorrhoea rate among gay and bisexual men who have sex with men (MSM) has been increasing rapidly in many Western countries. Furthermore, gonorrhoea is becoming increasingly resistant to antibiotics and only limited options remain for treatment. Recent evidence suggests that the oropharynx may play an important role in gonorrhoea transmission. It is hypothesised that reducing the prevalence of oropharyngeal gonorrhoea will also reduce the population incidence of gonorrhoea. Mouthwash has been proposed as a novel non-antibiotic intervention to prevent oropharyngeal gonorrhoea; hence, reducing the probability of antibiotic resistance developing. However, its efficacy is yet to be confirmed by a randomised controlled trial – the findings of which will be available in 2019. If the trial shows mouthwash is effective in preventing gonorrhoea, this finding could potentially be translated into a public health campaign to increase the mouthwash use in the MSM population. This article summarises the current evidence of the effectiveness of mouthwash against gonorrhoea and discusses the potential literature gaps before implementing the mouthwash intervention at a population level.

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“…Use of chewing sticks or neem twigs leads to infrequent tooth cleaning is a prime cause of oral cancer. 23…”

Section: Internal Environmentmentioning

confidence: 99%

Early detection and prevention of oral cancer: an appraisal

Agrawal

Saxena

Jain

et al. 2019

Int J Community Med Public Health

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Oral cancers (OC) represent the majority of head and neck cancers with more than half million patients being affected each year worldwide. Oral squamous cell carcinoma is the sixth commonest cancer worldwide, accounting for approximately 4% of all cancers. Therefore, an improvement in the prevention and control of oral cancer is of critical importance. This may be achieved by reducing the risk through avoidance of tobacco and alcohol, recognizing and treating premalignant lesions and detecting developed OC at an early stage. Data search for the present review was done electronically. Electronic search was conducted using databases such as Pubmed and Medline, Cochrane library, articles published in peer-reviewed journals, text books, grey literature and from sites of World Health Organization, Centre For Diseases Control Report, Global Adult Tobacco Survey and Global Youth Tobacco Survey reports. This review ruled out web of causation and web of prevention including early detection and prevention to be an ideal strategy to reduce the prevalence of oral cancer and its impact on quality of life. Screening and early detection in population at risk have been proposed to decrease both morbidity and mortality associated with the oral cancer.

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Poor oral Hygiene may be the Sole Cause of Oral Cancer

Abstract: In the absence of other known carcinogens, poor oral hygiene may be the single factor that caused oral cancer in these subjects. Research is needed to investigate the pathological mechanism that is associated with this risk factor.

Cited by 34 publications

References 21 publications

Association between tooth loss and risk of oesophageal cancer: a dose–response meta-analysis

Association between tooth loss and risk of oesophageal cancer: a dose–response meta-analysis

Translating mouthwash use for gonorrhoea prevention into a public health campaign: identifying current knowledge and research gaps

Early detection and prevention of oral cancer: an appraisal

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