Popular Use of Traditional Chinese Medicine in HIV Patients in the HAART era

Ma, Kurtland; Lee, Shui Shan; Chu, E K Y; Tam, Dennise K.P.; Kwong, Victoria S. C.; Ho, Choi-Fung; Cheng, Kathy Lai Sim; Wong, Ka-Hing

doi:10.1007/s10461-007-9245-4

Cited by 12 publications

(13 citation statements)

References 16 publications

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“…This prevalence rate of CM use is somewhat lower than that observed in other commonly occurring chronic conditions in Chinese communities [17]–[19]. In non-CM-using patients, nearly 58% did not believe CM could help their condition, suggesting that the lower prevalence of CM use in schizophrenic population is mainly related to their negative attitude towards this traditional remedy.…”

Section: Discussionmentioning

confidence: 59%

An Epidemiological Study of Concomitant Use of Chinese Medicine and Antipsychotics in Schizophrenic Patients: Implication for Herb-Drug Interaction

et al. 2011

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BackgroundHerb-drug interactions are an important issue in drug safety and clinical practice. The aim of this epidemiological study was to characterize associations of clinical outcomes with concomitant herbal and antipsychotic use in patients with schizophrenia.Methods and FindingsIn this retrospective, cross-sectional study, 1795 patients with schizophrenia who were randomly selected from 17 psychiatric hospitals in China were interviewed face-to-face using a structured questionnaire. Association analyses were conducted to examine correlates between Chinese medicine (CM) use and demographic, clinical variables, antipsychotic medication mode, and clinical outcomes. The prevalence of concomitant CM and antipsychotic treatment was 36.4% [95% confidence interval (95% CI) 34.2%–38.6%]. Patients using concomitant CM had a significantly greater chance of improved outcomes than non-CM use (61.1% vs. 34.3%, OR = 3.44, 95% CI 2.80–4.24). However, a small but significant number of patients treated concomitantly with CM had a greater risk of developing worse outcomes (7.2% vs. 4.4%, OR = 2.06, 95% CI 2.06–4.83). Significant predictors for concomitant CM treatment-associated outcomes were residence in urban areas, paranoid psychosis, and exceeding 3 months of CM use. Herbal medicine regimens containing Radix Bupleuri, Fructus Gardenia, Fructus Schisandrae, Radix Rehmanniae, Akebia Caulis, and Semen Plantaginis in concomitant use with quetiapine, clozapine, and olanzepine were associated with nearly 60% of the risk of adverse outcomes.ConclusionsConcomitant herbal and antipsychotic treatment could produce either beneficial or adverse clinical effects in schizophrenic population. Potential herb-drug pharmacokinetic interactions need to be further evaluated.

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Section: Discussionmentioning

confidence: 59%

An Epidemiological Study of Concomitant Use of Chinese Medicine and Antipsychotics in Schizophrenic Patients: Implication for Herb-Drug Interaction

et al. 2011

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“…A study done in China on seventy-six male HIV patients on use of traditional Chinese medicine showed that all except one had achieved undetectable viral load [21]. …”

Section: Discussionmentioning

confidence: 99%

Pattern of Traditional Medicine Utilization among HIV/AIDS Patients on Antiretroviral Therapy at a University Hospital in Northwestern Ethiopia: A Cross‐Sectional Study

Gurmu

Teni

Tadesse

2017

Evidence-Based Complementary and Alternative Medicine

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The objective of this study was to assess traditional, complementary, and alternative medicine (TCAM) utilization pattern among HIV/AIDS patients on antiretroviral therapy at University of Gondar Comprehensive Specialized Hospital. Materials and Methods. Data on sociodemographic profile and clinical and TCAM utilization were collected using a structured, pretested questionnaire from April 01 to May 28, 2014, through interviews with patients. Data on CD4 count, HIV stage, and ART regimen were collected from patient records. Analysis was conducted descriptively using SPSS version 20. Results. Of the 300 participants, 43.7% reported using TCAM, with the largest proportion of them from religious institutions (churches/mosques) (41.22%), followed by home prepared (32.82%) and traditional healers (16.03%). The leading forms of TCAM used were spiritual and herbal therapies constituting 56.49% and 36.64% of the patients, respectively. The most frequently used herbal products included Nigella sativa (22.92%) and Moringa oleifera (20.83%). Most of the patients (73.30%) using TCAM reported improvement in their conditions. Conclusions. TCAM utilization among HIV/AIDS patients on ART was common and different sources and types were used alongside ART, with improvement reported by most. Further research is needed to identify CAM therapies which may be used as adjunct treatments among these patients.

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“…In 2005, a survey in Hong Kong showed that 59.2% of HIV/ AIDS patients use TCM, most patients using TCM for treatment of a minor illness (60.0%) and general healthcare (57.8%), while they chose western medicine for therapy of important disease [60].Although numerous studies have shown the efficacy of TCM for prevention of HIV infection and treatment of AIDS patients, few of these studies were strictly designed, and the evidence was inadequate. Also, some people doubted that whether there were any inhibitors for treatment of AIDS patients from Chinese's herbs.…”

Section: Summary and Perspectivesmentioning

confidence: 99%

Traditional Chinese Medicine as Prevention and Treatment Strategies of HIV Infection

Tan¹

2016

J. Drug

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Traditional Chinese medicine (TCM) has produced impressive responses in treatment of acquired immunodeficiency syndrome (AIDS) patients. However, various terms, such as principle, standard, assumption, convention, and concept, for TCM treatment are not accepted by conventional AIDS experts. The increasing popularity of TCM has also inspired horror about their toxicity and uncertainty of complex components. In this paper, the evidence of Chinese herbal treatment of AIDS patients and prevention of the spread of HIV was provided; an overview of the TCM practitioners' concepts of how TCM work was discussed. We reported fourteen relevant studies, including ten Chinese herbal compounds, and four TCM extracts. In the TCM's study, these aspects, including critically assessing the authenticity, strict quality assurance measures, feasible evaluation system of the acute and chronic toxicity and clinical efficacy, are very important. We believe that potential drugs derived from TCM will be found, and TCM will play a crucial role in the prevention and treatment of AIDS.

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Popular Use of Traditional Chinese Medicine in HIV Patients in the HAART era

Cited by 12 publications

References 16 publications

An Epidemiological Study of Concomitant Use of Chinese Medicine and Antipsychotics in Schizophrenic Patients: Implication for Herb-Drug Interaction

An Epidemiological Study of Concomitant Use of Chinese Medicine and Antipsychotics in Schizophrenic Patients: Implication for Herb-Drug Interaction

Pattern of Traditional Medicine Utilization among HIV/AIDS Patients on Antiretroviral Therapy at a University Hospital in Northwestern Ethiopia: A Cross‐Sectional Study

Traditional Chinese Medicine as Prevention and Treatment Strategies of HIV Infection

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