Population-Based Study on the Epidemiology of Ménière's Disease

Bruderer, Saskia Gabriela; Bodmer, Daniel; Stohler, Nadja A; Jick, Susan S.; Meier, Christoph

doi:10.1159/000475875

Cited by 70 publications

(61 citation statements)

References 32 publications

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“…16 Moreover, a consistent higher prevalence of migraine in MD has been reported. 41 Furthermore, there have been described cases of MD patients with associated vestibular migraine, suggesting a shared pathophysiology. [42][43][44] This observation could be explained if patients with the overlapping syndrome share some common allelic variants with pleiotropic effects on the brain and the inner ear.…”

Section: Other Comorbidities In MDmentioning

confidence: 99%

Current Understanding and Clinical Management of Meniere's Disease: A Systematic Review

Pérez-Carpena

Lopez-Escamez

2019

Semin Neurol

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Meniere's disease (MD) is a set of uncommon disorders with core phenotype of tinnitus, episodic vertigo, and sensorineural hearing loss. MD shows a genetic predisposition and a family history is found in 10% cases, with an autosomal dominant inheritance pattern. It is a multifactorial condition whose onset and development are triggered by the combined effect of genetic and environmental factors. Histopathological studies have associated MD with the accumulation of endolymph in the cochlea and the vestibular organs. However, endolymphatic hydrops does not fully explain the persistence of tinnitus, hearing loss progression, or the frequency of vertigo attacks.There are several comorbidities associated with MD, such as migraine, anxiety, autoimmune, and autoinflammatory disorders, adding more complexity to the phenotype. This “extended phenotype” can make the diagnosis and clinical management more complex, but it could also lead to a better characterization, understanding, and treatment of MD patients.We have conducted a systematic review on MD to update current knowledge, focusing on its mechanisms, diagnosis, comorbidities, and practical management.

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Section: Other Comorbidities In MDmentioning

confidence: 99%

Current Understanding and Clinical Management of Meniere's Disease: A Systematic Review

Pérez-Carpena

Lopez-Escamez

2019

Semin Neurol

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“…Similar findings of increased prevalence of anxiety and depression were reported in population based epidemiological studies as well. 19 Despite using a methodology involving a structured psychiatric instrument, patients with MD and MV showed significantly higher prevalence of psychiatric comorbidity (MD=57%, MV=65%) especially anxiety and depressive disorders, than patients with VN (22%), BPPV (15%) and normal subjects (20%). 20 Confirmation of increased prevalence of mental health problems was obtained from larger studies as well.…”

Section: Discussionmentioning

confidence: 92%

Anxiety and depression associated with vertigo: a cross sectional study from India

Asha

Kumar

Punnoose

et al. 2019

Int J Otorhinolaryngol Head Neck Surg

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Background: Vertigo is a common clinical symptom in the community as well as in specialist settings. Depression and anxiety are common among vertigo patients and have a significant impact on the course of illness.Methods: This study was conducted at the outpatient clinics of Department of ENT, Government Medical College, Kottayam. Zung self-rating anxiety and Zung self-rating depression scales were used. Results: There were 158 patients in the study. The commonest diagnosis was benign paroxysmal positional vertigo (BPPV) (76; 48.1%) followed by migrainous vertigo (MV) (41; 25.9%), Meniere’s disease (MD) (31; 19.6%) and vestibular neuronitis (VN) (10; 6.3%). 74 (46.83%) patients had depression. Depression was most prevalent among MD (26; 83.87%) followed by MV (29; 70.73%). Mean depression score was highest with MD (58; SD=8.136) followed by MV (54.29; SD=10.441). 70 (44.03%) patients had anxiety. 50 being women and 20 men. A diagnosis of anxiety was most common in MD (25; 80.6%) followed by MV (33; 80.5%). Mean anxiety score was highest in MD (56.48; SD=11.003) followed by MV (54.15; SD=12.041), A diagnosis of anxiety was most common among patients with MD (25; 80.6%) followed by MV (33; 80.5%).Conclusions: There is a high prevalence of depression and anxiety in Meniere’s disease and migrainous vertigo in India as evidenced by this study. Identification and appropriate management of coexisting mental health problems to address the disability, poor quality of life and protracted course is an integral part of managing vertigo.

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“…In previous studies, the estimated prevalence of MD ranged from 17 to 513 per 100,000 [Havia et al, 2005;Shojaku et al, 2005;Radtke et al, 2008;Harris and Alexander, 2010;Bruderer et al, 2017;Guerra-Jiménez et al, 2017;Tyrrell et al, 2014]. The epidemiology of MD is variable according to the methodological differences, changes over time in diagnostic criteria, and populations surveyed.…”

Section: Introductionmentioning

confidence: 99%

Epidemiology and Seasonal Variation of Ménière’s Disease: Data from a Population-Based Study

Kim

Cheon

2020

Audiol Neurotol

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Introduction: Ménière’s disease (MD) is a disease of the inner ear. In Asian countries, there is one previous epidemiologic study that used a retrospective survey of a specific district. Previous studies have demonstrated that weather variables are strongly associated with symptom aggravation in MD. However, no study has reported on seasonal variation of MD. Methods: We conducted a retrospective population-based study using the Korean national health insurance claims database (NHICD). In the present study, the prevalence and incidence of MD from 2013 to 2017 were calculated. Prevalence and incidence of MD according to sex, age group, and monthly incidence are presented. Seasonal incidence was calculated for four seasons. The seasonal average humidity and atmospheric pressure were also calculated. Results: The incidence rate of MD showed a rapid yearly increase from 2013 to 2017 in Korea. The prevalence and incidence rate by age group continued to increase up to the 70 year olds. The female-to-male ratio was 2.17. The seasonal incidence of MD was relatively high in summer and autumn and relatively low in winter and spring; however, there were no significant differences. Discussion/Conclusions: The rapid progression to an aging society, increase in medical accessibility, and lifestyle changes could be the reasons for the elevation of the incidence rate in the Korean population. Consistent with a previous study, the incidence of MD was higher in seasons with high humidity and low atmospheric pressure; however, there were no significant differences. Further studies about the relationship between diet and MD, seasonality of MD with long-term analysis, and investigating the underlying mechanisms connecting weather and MD are needed.

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Population-Based Study on the Epidemiology of Ménière's Disease

Cited by 70 publications

References 32 publications

Current Understanding and Clinical Management of Meniere's Disease: A Systematic Review

Current Understanding and Clinical Management of Meniere's Disease: A Systematic Review

Anxiety and depression associated with vertigo: a cross sectional study from India

Epidemiology and Seasonal Variation of Ménière’s Disease: Data from a Population-Based Study

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