Population Data on the Thirteen CODIS Core Short Tandem Repeat Loci in African Americans, U.S. Caucasians, Hispanics, Bahamians, Jamaicans, and Trinidadians

Abstract

Allele distributions for 13 tetrameric short tandem repeat (STR) loci, CSF1PO, FGA, TH01, TPOX, VWA, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, and D21S11, were determined in African American, United States Caucasian, Hispanic, Bahamian, Jamaican, and Trinidadian sample populations. There was little evidence for departures from Hardy-Weinberg expectations (HWE) in any of the populations. Based on the exact test, the loci that departed significantly from HWE are: D21S11 (p = 0.010, Bahamians); CSF1PO (p = 0.014, Trinidadians); TPOX (p = 0.011, Jamaicans and p = 0.035, U.S. Caucasians); and D16S539 (p = 0.043, Bahamians). After employing the Bonferroni correction for the number of loci analyzed (i.e., 13 loci per database), these observations are not likely to be significant. There is little evidence for association of alleles between the loci in these databases. The allelic frequency data are similar to other comparable data within the same major population group.

Discrimination of common bean cultivars using multiplexed microsatellite markers

“…The standardization of accurate microsatellite genotyping systems that can be used in different laboratories and the effective use of the generated molecular profiles as descriptors for a particular crop of interest require validation steps to confirm that the same molecular patterns are obtained at different institutions. For instance, the establishment of a typing system in humans for forensic purposes was the result of an organized validation effort involving a number of laboratories worldwide (Kimpton et al, 1996), which yielded a set of 13 internationally recommended SSRs (Budowle et al, 1999). A similar study conducted for Eucalyptus involving an international network of laboratories in eight countries resulted in a set of 25 SSRs for the characterization of this genus, with six loci P.C.B.…”

Genetic Differentiation of the Cabo Verde Archipelago Population Analysed by STR Polymorphisms

“…Finally allele 7 of D13S317, which appears in one individual from Santiago Is. (CVS), has only been spotted in Bahamians and Jamaicans (Budowle et al 1999). Results from the admixture analysis show an extremely high percentage of the p 1 contribution to the Cabo Verde gene pool (Table 3).…”

A Large Population Genetic Study of 15 Autosomal Short Tandem Repeat Loci for Establishment of Korean DNA Profile Database

“…Further, two Chinese populations revealed that a relatively small number of loci were different from Koreans: a Shanghai population differed at 6 loci (Li et al, 2009) and a Yunnan Han China population at 4 loci (Nie et al, 2008). Although, a Southwestern American Hispanic population showed significant differences at only 5 loci (Budowle et al, 1999), the R st values indicated that two Chinese populations are more close to Korean population than American Hispanic population (R st value: Shanghai, 0.00301; Yunnan-Han, 0.00147; US Hispanic, 0.02589).…”

“…Allele frequencies of most loci in the Korean population were significantly different from those in European or American populations (p < 0.05). For example, by comparisons of a Korean population, Greek (Sánchez-Diz et al, 2008) and Brazilian populations differed at 12 loci (Fridman et al, 2008), while US Caucasian and African-American populations differed at 11 STR loci (Budowle et al, 1999). Further, two Chinese populations revealed that a relatively small number of loci were different from Koreans: a Shanghai population differed at 6 loci (Li et al, 2009) and a Yunnan Han China population at 4 loci (Nie et al, 2008).…”