Population screening for chronic kidney disease: a survey involving 38 721 Brazilians

Lima, A.O; Kesrouani, Silvana; Gomes, R. A.; Cruz, Jenner; Kirsztajn, Gianna Mastroianni

doi:10.1093/ndt/gfs063

Cited by 9 publications

(4 citation statements)

References 11 publications

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“…The semi-quantitative dipstick method of albuminuria assessment without confirmation test, the bias in reading the results and the presence of transient proteinuria could explain this high prevalence. Nevertheless, some authors have also reported low prevalence of albuminuria on dipstick with prevalence ranging from 2.25 to 7.4 %, which could reflect true lower risk of albuminuria in their population as well as bias in reading the results [ 10 , 11 , 25 , 27 ].…”

Section: Discussionmentioning

confidence: 99%

Prevalence and determinants of chronic kidney disease in rural and urban Cameroonians: a cross-sectional study

Kaze

Meto²,

Halle

et al. 2015

BMC Nephrol

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BackgroundChronic kidney disease (CKD) is a global public health problem that disproportionally affects people of African ethnicity. We assessed the prevalence and determinants of CKD and albuminuria in urban and rural adults Cameroonians.MethodsThis was a cross-sectional study of 6-month duration (February to July 2014), conducted in the health district of Dschang (Western Region of Cameroon), using a multistage cluster sampling. All adults diagnosed with albuminuria (≥30 mg/g) and/or decreased estimated glomerular filtration rate (eGFR) (<60 ml/min/1.73 m2) were re-examined three months later. Logistic regression models were used to relate baseline characteristics with prevalent CKD.ResultsWe included 439 participants with a mean age of 47 ± 16.1 years; with 185 (42.1 %) being men and 119 (27.1 %) being urban dwellers. There was a high prevalence of hypertension (25.5 %), diabetes (9.8 %), smoking (9.3 %), alcohol consumption (59.7 %), longstanding use of herbal medicine (90.9 %) and street medications (87.5 %), and overweight/obesity (53.3 %) which were predominant in rural area. The prevalence of CKD was 13.2 % overall, 14.1 % in rural and 10.9 % in urban participants. Equivalents figures for CKD stages G3-G4 and albuminuria were 2.5 %, 1.6 % and 5.0 %; and 12.1 %, 14.1 % and 6.7 % respectively. Existing hypertension and diabetes were associated with all outcomes. Elevated systolic blood pressure and the presence of hypertension and diabetes were the predictors of albuminuria and CKD while urban residence was associated with CKD stages G3-G4.ConclusionThe prevalence of CKD and albuminuria was high in this population, predominantly in rural area, and driven mostly by the commonest risk factors.Electronic supplementary materialThe online version of this article (doi:10.1186/s12882-015-0111-8) contains supplementary material, which is available to authorized users.

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Section: Discussionmentioning

confidence: 99%

Prevalence and determinants of chronic kidney disease in rural and urban Cameroonians: a cross-sectional study

Kaze

Meto²,

Halle

et al. 2015

BMC Nephrol

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“…In a survey of Brazilian adults participating in CKD prevention campaigns (mean age 45±22 years), 7.3% of the 37,771 urine samples examined showed proteinuria. [ 3 ] The estimated prevalence of patients on chronic dialysis in Brazil in 2012 was 503 per million, with 31.9% aged ≥ 65 years. [ 4 ]…”

Section: Introductionmentioning

confidence: 99%

Aging and decreased glomerular filtration rate: An elderly population-based study

et al. 2017

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BackgroundAlthough a reduced glomerular filtration rate (GFR) in old people has been attributed to physiologic aging, it may be associated with kidney disease or superimposed comorbidities. This study aims to assess the prevalence of decreased GFR in a geriatric population in a developing country and its prevalence in the absence of simultaneous diseases.Study design and methodsThis is a cross-sectional study of data from the Saúde, Bem-Estar e Envelhecimento cohort study (SABE study[Health, Well-Being and Aging]), a multiple cohorts study. A multistage cluster sample composed of 1,253 individuals representative of 1,249,388 inhabitants of São Paulo city aged ≥60 years in 2010 was analyzed. The participants answered a survey on socio-demographic factors and health, had blood pressure measured and urine and blood samples collected. GFR was estimated and defined as decreased when <60 mL/min/1.73m2. Kidney damage was defined as dipstick-positive hematuria or urinary protein:creatinine > 0.20 g/g.ResultsThe prevalence of GFR <60 mL/min/1.73m2 was 19.3%. Individuals with GFR <60 mL/min/1.73m2 were older (75±1 versus 69±1 years, p<0.001), had lower schooling (18 versus 30% with complete 8-year basic cycle, p = 0.010), and higher prevalence of hypertension (82 versus 63%, p<0.001), diabetes (34 versus 26%, p = 0.021), cardiovascular disease (43 versus 24%, p<0.001) and kidney damage (35% versus 15%, p<0.001). Only 0.7% of the entire studied population had GFR <60 mL/min/1.73m2 without simultaneous diseases or kidney damage. Among the individuals with GFR <60 mL/min/1.73m2, 3.5% had neither renal damage nor associated comorbidities, whereas among those with GFR ≥60 mL/min/1.73m2, 11.0% had none of these conditions. Logistic regression showed that older age, cardiovascular disease and hypertension were associated with GFR<60 mL/min/1.73m2.ConclusionsDecreased GFR was highly prevalent among the geriatric population in a megalopolis of a developing country. It was rarely present without simultaneous chronic comorbidities or kidney damage.

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“…In Juiz de Fora (MG) the prevalence of CKD in individuals aged more than 18 years was 9.6% 9 , and in São Paulo (SP) the prevalence in adults was 8.4% 28 .…”

Section: Discussionmentioning

confidence: 99%

“…However, some studies find higher prevalences of CKD, ranging from 15.3% in a community of ethnic minorities in China 32 to 21.8% in Iran 33 . Hence, the prevalence of CKD in the global population, especially in developing 28,30,33,35 . This difference between the prevalences can be explained by the fact that albuminuria increases gradually according to age and many studies did not include older adults.…”

Section: Discussionmentioning

confidence: 99%

Anthropometric measurements and markers of renal function in adults and older adults

et al. 2016

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A B S T R A C T ObjectiveTo determine whether anthropometric indicators are associated with markers of renal function in adults and older adults. MethodsThis cross-sectional study included 279 adults and older adults attending eight primary healthcare units in eastern Goiânia, Góias. Sociodemographic, lifestyle, and clinical data were collected using a standard questionnaire. Body mass index was categorized as overweight (≥25 kg/m²) or non-overweight. Waist circumference was classified as normal or high; chronic kidney disease was defined as a glomerular filtration rate below 60 mL/minutes/1.73 m²; micro/macroalbuminuria was defined as an albumin/creatinine ratio above 30 mg/g. The association between anthropometric indicators and renal function markers was assessed by multiple linear regression analysis. ResultsChronic kidney disease was present in 8.9% and micro/macroalbuminuria in 34.8% of the sample. The prevalence of overweight was 57.0%. Waist circumference and body mass index were positively associated with glomerular

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Population screening for chronic kidney disease: a survey involving 38 721 Brazilians

Abstract: This initiative provided information on proteinuria and possible cases of CKD based on a large sampling of the Brazilian population. Proteinuria was detected in 7.3% of these individuals, and such prevalence is similar to that previously described in developed countries.

Cited by 9 publications

References 11 publications

Prevalence and determinants of chronic kidney disease in rural and urban Cameroonians: a cross-sectional study

Prevalence and determinants of chronic kidney disease in rural and urban Cameroonians: a cross-sectional study

Aging and decreased glomerular filtration rate: An elderly population-based study

Anthropometric measurements and markers of renal function in adults and older adults

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