Porcine Parainfluenza Virus Type 1 (PPIV-1) in U.S. Swine: Summary of Veterinary Diagnostic Laboratory Data

Welch, Michael; Park, Jie; Gauger, Phillip C.; Harmon, Karen M.; Lin, Kevin Y.; Piñeyro, Pablo; Zhang, Jianqiang

doi:10.31274/ans_air-180814-389

Cited by 5 publications

(11 citation statements)

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“…Furthermore, within BS-1 we were also able to identify a co-infection with PRRSV. Co-infections with PRRSV and/or SIV have been reported previously (Lau et al, 2013;Welch et al, 2017), with PPIV-1 being speculated to play a synergistic role within the porcine respiratory disease complex. However, the role of these co-infections in the porcine respiratory disease complex remains to be ascertained (Park et al, 2019;Welch et al, 2017).…”

Section: Country Of Originmentioning

confidence: 95%

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First detection of porcine respirovirus 1 in Germany and the Netherlands

Schuele

Lizarazo-Forero

Cassidy

et al. 2021

Transbound Emerg Dis

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Porcine respirovirus 1, also referred to as porcine parainfluenza virus 1 (PPIV-1), was first detected in deceased pigs from Hong Kong in 2013. It has since then been found in the USA, Chile and most recently in Hungary. Information on the pathogenicity and global spread is sparse. However, it has been speculated to play a role in the porcine respiratory disease complex. To investigate the porcine virome, we screened 53 pig samples from 26 farms within the Dutch-German border region using shotgun metagenomics sequencing (SMg). After detecting PPIV-1 in five farms through SMg, a real-time reverse transcriptase PCR (RT-qPCR) assay was designed, which not only confirmed the presence of the virus in 1 of the 5 farms but found an additional 6 positive farms. Phylogenetic analysis found the closest match to be the first detected PPIV-1 strain in Hong Kong. The Dutch-German region represents a significant area of pig farming within Europe and could provide important information on the characterization and circulation of porcine viruses, such as PPIV-1. With its recent detection in Hungary, these findings suggest widespread circulation of PPIV-1 in Central Europe, highlighting the need for further research on persistence, pathogenicity and transmission in Europe.

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Section: Country Of Originmentioning

confidence: 95%

“…Viruses that belong to the Paramyxoviridae family have been associated with respiratory symptoms in farm animals and may cross host species barriers (Welch et al., 2017 ). Porcine respirovirus 1, also referred to as porcine parainfluenza virus 1 (PPIV‐1), belongs to the Respirovirus genus within the Paramyxoviridae family.…”

Section: Introductionmentioning

confidence: 99%

First detection of porcine respirovirus 1 in Germany and the Netherlands

Schuele

Lizarazo-Forero

Cassidy

et al. 2021

Transbound Emerg Dis

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“…However, SMg was able to recover part of the genome for other co-detections; PRRSV (Ct 26) was recovered from the BS sample and SIV (Ct 19 and 21) was recovered from the NS samples (Table 1). Co-infections with PRRSV and/or SIV have been reported previously (Lau et al, 2013;Welch et al, 2017) but the role of these co-infections in the porcine respiratory disease complex remains to be ascertained (Welch et al, 2017;Park et al, 2019). It must be noted that samples in this study were pooled, and as such, viruses/co-infections cannot necessarily be linked to an individual animal.…”

Section: Resultsmentioning

confidence: 93%

“…Viruses that belong to the Paramyxoviridae family have been associated with respiratory symptoms in farm animals and may cross host species barriers (Welch et al, 2017). Porcine respirovirus 1 (PRV1), also referred to as porcine parainfluenza 1, belongs to the Respirovirus genus within the Paramyxoviridae family.…”

Section: Introductionmentioning

confidence: 99%

“…While the pathogenicity of PRV1 in pigs is still unclear, it has been isolated from pigs with respiratory symptoms (Lau et al, 2013). Moreover, it has been detected in co-infections with swine influenza virus (SIV) and porcine reproductive and respiratory syndrome virus (PRRSV), which suggests it could also play a role within the porcine respiratory disease complex (Welch et al, 2017). However, information on the global spread and epidemiology is sparse.…”

Section: Introductionmentioning

confidence: 99%

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First detection of porcine respirovirus 1 in Germany and in the Netherlands

Schuele¹,

Lizarazo²,

Cassidy³

et al. 2020

Preprint

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PRV1 was first detected in deceased pigs from Hong Kong in 2013. It has since been detected in the USA, Chile and most recently in Hungary. Information on the pathogenicity and global spread is sparse, however it has been speculated to play a role in the porcine respiratory disease complex. In an effort to investigate the porcine virome, we screened 53 pig samples from 29 farms using SMg within the Dutch/German border region. In five farms we detected PRV1. qPCR confirmed the presence of the virus in 2 of these farms and found an additional 6 positive farms. Phylogenetic analysis found the closest match to the first detected PRV1 strain in Hong Kong. The Dutch/German region represents a major area of pig farming within Europe and could provide important information on the characterization and circulation of porcine viruses, such as PRV1. Together with the recent detection of PRV1 in Hungary, these findings suggest widespread of PRV1 in Central Europe, highlighting the need for further research on persistence, pathogenicity and transmission in Europe.

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First report of Porcine respirovirus 1 in South Korea

Park

Kim

et al. 2022

Transbounding Emerging Dis

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Porcine respirovirus 1 (PRV1) is a recently emerging porcine respiratory virus that belongs to the genus Respirovirus of the Paramyxoviridae family. Since its first detection in Hong Kong, China in 2009, PRV1 has been subsequently identified in several American and European countries, suggesting that the emerging virus may have been globally distributed. However, in Asia, the virus has been reported only in China. Here, we report that PRV1 was first detected in pigs from 16 farms located in seven provinces across Korea, with a prevalence of 71.4% based on the tested oral fluid samples, suggesting that the virus is already widespread in Korean pig herds. For further genetic characterization of the Korean PRV1 strains, a complete genome and two F gene sequences were obtained from PRV1-positive samples collected from three different pig farms. Phylogenetic analysis based on the complete genome and F gene sequences showed that all three Korean PRV1 strains were grouped into European lineage 1 and were closely related to strains from Hong Kong (China), Germany and Poland. We could not obtain evidence for the origin of Korean PRV1 because of the limited availability of PRV1 sequences. In conclusion, PRV1 was first identified in Korean pig herds and genetically characterized in the present study. These results contribute to a better understanding of the global geographical distribution and genetic characteristics of PRV1.

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Porcine Parainfluenza Virus Type 1 (PPIV-1) in U.S. Swine: Summary of Veterinary Diagnostic Laboratory Data

Cited by 5 publications

References 0 publications

First detection of porcine respirovirus 1 in Germany and the Netherlands

First detection of porcine respirovirus 1 in Germany and the Netherlands

First detection of porcine respirovirus 1 in Germany and in the Netherlands

First report of Porcine respirovirus 1 in South Korea

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