Portable low-cost open-source wireless spectrophotometer for fast and reliable measurements

Laganovska, Katrīna; Zolotarjovs, Aleksejs; Vázquez, Mercedes; Donnell, Kirsty Mc; Liepiņš, Jānis; Ben‐Yoav, Hadar; Karitans, Varis; Smits, Krisjanis

doi:10.1016/j.ohx.2020.e00108

Cited by 66 publications

(47 citation statements)

References 20 publications

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“…Portable low-cost open-source wireless spectrophotometer for fast and reliable Measurements (17) € 225 Development of a Low-Cost UV-Vis Spectrophotometer and Its Application for the Detection of Mercuric Ions Assisted by Chemosensors (18) US$ 86 (15,19) used Arduino as a controller Cost will be high…”

Section: Circuit Analysismentioning

confidence: 99%

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A low-cost absorbance measurement device using microcontroller

Shree¹,

Shinde²

2021

IJST

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Objectives: To design a low-cost absorbance measurement device using a microcontroller that can be used for student's learning. Methods/Statistical analysis: The setup device is designed based upon Beer-Lambert Law with some LEDs through various sample solutions along with LDR at a different range of wavelength and the results are shown on a 16x2 LCD by use of a PIC16F877a microcontroller. The results are also compared with the standard colorimetric method. Findings: The setup device able to measure the absorbance of different colors of sample solutions at a wide range of wavelength (400-700nm) and measured by utilizing different LEDs to the transmitter end and an LDR at the receiver end. The proposed experimental device's performance was compared with the standard colorimeter for efficiency check. The efficiency of the setup device is near to the colorimeter of more than 95%. Novelty/Applications: For educational purpose, the proposed setup device is well affordable due to low cost (US$10.98) and easy to maintain because of compact size and data acquisition directly through microcontroller.

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Section: Circuit Analysismentioning

confidence: 99%

“…(15) The electronics field is an interesting concern among innovation designers. (16) The microcontroller is a fundamental part of automated devices, where it controls and minimizes manual activity.In (17)(18)(19) , utilize Arduino as a microcontroller (µc) which is costly as compared to the PIC microcontroller.…”

Section: Introductionmentioning

confidence: 99%

A low-cost absorbance measurement device using microcontroller

Shree¹,

Shinde²

2021

IJST

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“…These devices are SCiO manufactured by Consumer Physics, LinkSquare manufactured by Stratio, Inc., Tellspec spectrometer manufactured by Tellspec, Inc. and a personal spectrometer developed on the basis of the open source project [26].…”

Section: Developing a Prototype Systemmentioning

confidence: 99%

“…Of course, a device with a very high cost will not be as much in demand and widespread as one with a small cost. Today there are already examples of devices for spectrometric analysis with low cost and small size [25,26].…”

Section: Introductionmentioning

confidence: 99%

Prototype Design and Experimental Evaluation e-Healthcare System based on Molecular Analysis Devices

Zakharov¹,

Paramonov²,

Muthanna³

et al. 2021

IJACSA

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Recently, wireless body area networks (WBANs) and mobile Internet of Things (IoT) have been greatly increased and integrated into a different type of systems such as electronic/mobile-healthcare (e/m-healthcare) systems. In addition, analyzing the composition of drugs or performing the medical rapid tests in the conditions field are the main tasks of the m-healthcare system, in which the traditional laboratory methods of analysis are not suitable. Therefore, in this study, we proposed a novel structure with a distributed e-health system to perform such analysis, where portable infrared micro spectrometers are utilized and then boundary calculations are applied. More specifically, this system is proposed to use a portable infrared micro spectrometer with a specially designed application connected to a public communication network, which can process the results of analysis using boundary calculations. Moreover, it provides remote processing and long-term storage of analysis data using artificial neural networks and cloud technologies. Finally, simulation results show that preprocessing (error checking), data buffering and Edge Computing can significantly reduce the network latency and volume of transferred data.

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“… 9 − 11 Other groups have developed low-cost, wireless spectrophotometers to perform more quantitative measurements. 12 , 13 However, the use of a mini-spectrophotometer in the design can make the device cost-prohibitive for use in an at-home setting.…”

Section: Introductionmentioning

confidence: 99%

Toward a Quantitative Colorimeter for Point-of-Care Nitrite Detection

Siu

Hsieh

et al. 2022

ACS Omega

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This paper reports on a low-cost, quantitative, point-of-care solution for the early detection of nitrite, a common biomarker for urinary tract infections (UTIs). In a healthy individual, nitrite is not found in the urine. However, a subject with a suspected UTI will produce nitrite in their urine since the bacteria present will convert nitrate into nitrite. Traditionally, nitrite is monitored by urinary dipsticks that are either read by eye or using a reflectance spectrophotometer. Both methods provide a semiquantitative positive or negative result at best. In this paper, we described a novel, affordable, portable transmission-based colorimeter for the quantitative measurement of nitrite. A unique permutation of the Griess reaction was optimized for the clinical detection of nitrite in urine and is reported. By using nitrite spiked in a salt buffer, artificial, and human urine samples, the performance of the colorimeter was evaluated against dipsticks read using two commercial dipstick analyzers, Urisys 1100 (Roche Diagnostics) and Clinitek Status+ (Siemens Medical Solutions). The colorimeter was able to detect the clinically relevant range of nitrite from 0.78 to 200 μM in a salt buffer. The detection limit in artificial urine was determined as 1.6 μM, which is ∼16× more sensitive than commercial dipstick reflectance analyzers, enabling the possibility for earlier detection of urinary infections. The colorimeter is assembled using off-the-shelf components (<$80) and controlled by a smartphone application via low-energy bluetooth. It has a built-in color correction algorithm and is designed to enable for a turbidity correction in samples containing bacteria or other cellular debris as well. The mobile application can display the nitrite concentration for a single sample or display the results over a period of time. Tracking urinalysis results longitudinally can help identify trends such as increases in nitrite concentrations over an individual’s baseline and identify possible infections earlier. While the detection of nitrite was showcased here, this portable analyzer can be expanded to other colorimetric-based chemistries to detect a panel of biomarkers, which can improve the overall sensitivity and specificity of the desired assay.

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Portable low-cost open-source wireless spectrophotometer for fast and reliable measurements

Cited by 66 publications

References 20 publications

A low-cost absorbance measurement device using microcontroller

A low-cost absorbance measurement device using microcontroller

Prototype Design and Experimental Evaluation e-Healthcare System based on Molecular Analysis Devices

Toward a Quantitative Colorimeter for Point-of-Care Nitrite Detection

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