Portable measurement system for silicon nanowire field-effect transistor-based biosensors

In this study we present packaging techniques for SD-card form factor test adapters. Our test adapters consist of FETbased biochemical sensors and a CMOS integrated analog multiplexer connected to a printed circuit board (PCB). Protection of the test adapter is required for long term stability and reliable measurements of the biochemical sensor in a liquid environment. Two different encapsulation techniques and biocompatible materials with different thermomechanical properties were used for this purpose. Adhesive strength measurements of these encapsulants on different substrates were carried out.Finally, the package was integrated into a portable measurement system for multiplexed measurements. Measured gate characteristics were compared between blank and packaged test adapters. FET characteristics were measured in dry as well as in liquid environment.Our packaging technique is mechanically stable, suitable for measurements in liquid environments influences neither the electrical characteristics of the FET devices as nor data acquisition.

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“…This SDcard adapter is plugged into the portable measurement system using standard SD-Card contacts [7].…”

Section: Biochemical Sensor Integrationmentioning

confidence: 99%

Package characterization of FET-based biochemical sensors

Voitsekhivska

Suthau

Kirsten

et al. 2014

2014 IEEE 16th Electronics Packaging Technology Conference (EPTC)

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Hybrid Silicon Nanowire Devices and Their Functional Diversity

et al. 2019

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In the pool of nanostructured materials, silicon nanostructures are known as conventionally used building blocks of commercially available electronic devices. Their application areas span from miniaturized elements of devices and circuits to ultrasensitive biosensors for diagnostics. In this Review, the current trends in the developments of silicon nanowire‐based devices are summarized, and their functionalities, novel architectures, and applications are discussed from the point of view of analog electronics, arisen from the ability of (bio)chemical gating of the carrier channel. Hybrid nanowire‐based devices are introduced and described as systems decorated by, e.g., organic complexes (biomolecules, polymers, and organic films), aimed to substantially extend their functionality, compared to traditional systems. Their functional diversity is explored considering their architecture as well as areas of their applications, outlining several groups of devices that benefit from the coatings. The first group is the biosensors that are able to represent label‐free assays thanks to the attached biological receptors. The second group is represented by devices for optoelectronics that acquire higher optical sensitivity or efficiency due to the specific photosensitive decoration of the nanowires. Finally, the so‐called new bioinspired neuromorphic devices are shown, which are aimed to mimic the functions of the biological cells, e.g., neurons and synapses.

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