Portable smartphone platform based on tunable chiral fluorescent carbon dots for visual detection of L-Asp and L-Lys

Wei, Shanshan; Wang, Bin; Zhang, Hongyuan; Wang, Chenzhao; Cui, Shufeng; Yin, Xiangyu; Jiang, Chunzhu; Sun, Guoying

doi:10.1016/j.cej.2023.143103

Cited by 33 publications

(8 citation statements)

References 57 publications

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“…In addition, smartphone color identifiers enable a more accurate visual detection to compensate for the inability of the naked eye to discriminate subtle color deficiencies, making R-L-CDs promising candidates for application as biosensors (Figure 18a). 659 CQDs prepared using CA and other organic small molecules as carbon sources can have unexpected advantages. For instance, Ge et al developed ultrasmall permeable CQDs with a NIR-II window photothermal irradiation and good biocompatibility using CA and urea, which produce a sufficient photothermal effect to ablate tumors under laser irradiation at 1064 nm without damaging healthy tissues.…”

Section: Sensing and Imaging Applications Of Cds-based Sensorsmentioning

confidence: 99%

“…In particular, chiral red light CDs (R-L-CDs) can be used as fluorescent probes for rapidly identifying l -aspartate ( l -Asp) and l -Lys in water and biological samples. In addition, smartphone color identifiers enable a more accurate visual detection to compensate for the inability of the naked eye to discriminate subtle color deficiencies, making R-L-CDs promising candidates for application as biosensors (Figure a) …”

Section: Sensing and Imaging Applications Of Cds-based Sensorsmentioning

confidence: 99%

“…(a) One-step preparation of multicolor CDs and the fluorescence quenching and recovery process of R-L-CDs in presence and absence of l -Asp and l -Lys. Reproduced with permission from ref . Copyright 2023 Elsevier.…”

Section: Sensing and Imaging Applications Of Cds-based Sensorsmentioning

confidence: 99%

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Zero-Dimensional Carbon Nanomaterials for Fluorescent Sensing and Imaging

Yang,

Xu,

et al. 2023

Chem. Rev.

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Advances in nanotechnology and nanomaterials have attracted considerable interest and play key roles in scientific innovations in diverse fields. In particular, increased attention has been focused on carbon-based nanomaterials exhibiting diverse extended structures and unique properties. Among these materials, zero-dimensional structures, including fullerenes, carbon nano-onions, carbon nanodiamonds, and carbon dots, possess excellent bioaffinities and superior fluorescence properties that make these structures suitable for application to environmental and biological sensing, imaging, and therapeutics. This review provides a systematic overview of the classification and structural properties, design principles and preparation methods, and optical properties and sensing applications of zero-dimensional carbon nanomaterials. Recent interesting breakthroughs in the sensitive and selective sensing and imaging of heavy metal pollutants, hazardous substances, and bioactive molecules as well as applications in information encryption, super-resolution and photoacoustic imaging, and phototherapy and nanomedicine delivery are the main focus of this review. Finally, future challenges and prospects of these materials are highlighted and envisaged. This review presents a comprehensive basis and directions for designing, developing, and applying fascinating fluorescent sensors fabricated based on zero-dimensional carbon nanomaterials for specific requirements in numerous research fields.

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Section: Sensing and Imaging Applications Of Cds-based Sensorsmentioning

confidence: 99%

Section: Sensing and Imaging Applications Of Cds-based Sensorsmentioning

confidence: 99%

See 1 more Smart Citation

Zero-Dimensional Carbon Nanomaterials for Fluorescent Sensing and Imaging

Yang,

Xu,

et al. 2023

Chem. Rev.

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show abstract

“…The chiral carbon core of these nanomaterials can be functionalized by various biomolecules, such as proteins, antibodies, and nucleic acids, to enhance their targeting ability and selectivity for specific biological targets. The chirality of Ch-CDs can selectively interact with biological targets, making them useful in biosensing applications and making them highly sensitive and specific biosensors . The emission wavelength of Ch-CDs can be tuned by changing the size of the nanomaterial or by altering the surface functional groups, making them versatile tools for bioimaging applications.…”

Section: Application Of Ch-cds In Biomedical Engineeringmentioning

confidence: 99%

“…The chirality of Ch-CDs can selectively interact with biological targets, making them useful in biosensing applications and making them highly sensitive and specific biosensors. 74 The emission wavelength of Ch-CDs can be tuned by changing the size of the nanomaterial or by altering the surface functional groups, making them versatile tools for bioimaging applications.…”

Section: Application Of Ch-cds In Biomedical Engineeringmentioning

confidence: 99%

Recent Progress on Chiral Carbon Dots: Synthetic Strategies and Biomedical Applications

Chen,

Yu,

et al. 2023

ACS Biomater. Sci. Eng.

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The discovery of chiral carbon dots (Ch-CDs) has opened up an exciting new research direction in the field of carbon dots. It not only retains the chirality of the precursor and exhibits highly symmetric chiral optical properties but also has properties such as chemical stability, antibacterial and antitumor properties, and good biocompatibility of carbon dots. Based on these advantages, the application of Ch-CDs in the biomedical field has attracted significant interest among researchers. However, a comprehensive review of the selection of precursors for Ch-CDs, preparation methods, and applications in biomedical fields is still lacking. Here, we summarize their precursor selection and preparation methods based on recent reports on Ch-CDs and provide the first comprehensive review for specific applications in biomedical engineering, such as biosensing, bioimaging, drug carriers, antibacterial and antibiofilm, and enzyme activity modulation. Finally, we discuss application prospects and challenges that need to be overcome. We hope this review will provide valuable guidance for researchers to prepare novel Ch-CDs and facilitate their application in biomedical engineering.

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Carbon‐based nanodots for biomedical applications and clinical transformation prospects

Ding,

Xiao,

Ren

et al. 2024

BMEMat

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Carbon dots (CDs), emerging as a promising class of nanomaterials, have garnered significant interest in the field of biomedicine due to their unique physicochemical properties. This review provides a comprehensive overview of the recent advancements in the biomedical applications of CDs, emphasizing their potential for revolutionizing diagnostics, therapy, and bio‐imaging. We discuss the synthesis and functionalization of CDs, which are pivotal in tailoring their properties for specific biomedical applications. The applications of CDs in bioimaging include fluorescence imaging, magnetic resonance imaging, photoacoustic imaging, etc. Additionally, this review delves into the benefits of CDs in the treatment of diseases including cancer, inflammation and Alzheimer's, etc. Finally, we look forward to the future of CDs in the field of biomedicine, emphasizing the necessity of interdisciplinary collaboration to overcome current obstacles and facilitate the clinical translation of CDs‐based technologies. This review aims to provide a summary and perspectives on the latest developments of CDs in biomedicine, hoping to inspire further research in this rapidly advancing field.

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Portable smartphone platform based on tunable chiral fluorescent carbon dots for visual detection of L-Asp and L-Lys

Cited by 33 publications

References 57 publications

Zero-Dimensional Carbon Nanomaterials for Fluorescent Sensing and Imaging

Zero-Dimensional Carbon Nanomaterials for Fluorescent Sensing and Imaging

Recent Progress on Chiral Carbon Dots: Synthetic Strategies and Biomedical Applications

Carbon‐based nanodots for biomedical applications and clinical transformation prospects

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