Positive Affect and Letheby's Naturalization of Psychedelic Therapy

Abstract

Letheby’s naturalistic theory of psychedelic therapy argues that the therapeutic power of psychedelics lies in their ability to allow individuals “to discover the contingency, mutability and simulatory nature of their own sense of identity and habitual modes of attention.” The general shape of this project is persuasive; it is hard to see how the claim that successful therapy must involve changes to the self could be objected to, and Letheby sketches a consistent, if speculative, picture of psychedelic experience. But the role of affect in psychedelic therapy is insufficiently explored by Letheby as a comparison to MDMA-assisted therapy indicates. This comparison further suggests that Letheby’s reliance on a particular conceptualization of ego dissolution experiences is in need of further explanation and justification.

Predicting the Intensity of Psychedelic-Induced Mystical and Challenging Experience in a Healthy Population: An Exploratory Post-Hoc Analysis

“…We find no evidence that affect as measured by the PANAS predicts the experience of OBN or DED. 29 While the data available for this study did not include the factor of emotional excitability as referenced by Studerus et al, 28 this would be an area for future study.…”

“…It is therefore reasonable to assume that affect would have bearing on the outcome of a psychedelic experience. 29 According to the Positive and Negative Affect Scale [PANAS], 30 positive affects are defined as being interested, excited, strong, alert, enthusiastic, proud, inspired, determined, attentive, and active. Affects including being distressed, upset, guilty, hostile, irritable, ashamed, nervous, jittery, afraid, and scared are defined as negative.…”