Positron emission tomography as a tool for the 'tailored' management of retroperitoneal fibrosis: a nephro-urological experience

Piccoli, Giorgina Barbara; Consiglio, Valentina; Arena, Vincenzo; Pelosi, Ettore; Douroukas, Anastasios; Ragni, F.; Fiori, Cristian; Cortese, Gianfranco; Deagostini, Maria Chiara; Porpiglia, Francesco; Scarpa, R.M.

doi:10.1093/ndt/gfq051

Cited by 25 publications

(23 citation statements)

References 34 publications

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“…However, the possibility remains that both idiopathic retroperitoneal fibrosis and gastric cancer were coincidently coexistant in this patient. It has been reported that the sensitivity of positron emission tomography (PET) is very high for retroperitoneal fibrosis; however, it may not allow the distinction between retroperitoneal neoplastic tissue, eventually associated with retroperitoneal fibrosis, and metabolically active fibrotic tissue (14). The uptake of 67Ga, which is also known to accumulate malignant lesions, was found to be negative in the periaortic tissue in the present case.…”

Section: Discussioncontrasting

confidence: 59%

Retroperitoneal Fibrosis in a Patient with Gastric Cancer Manifested by Lower Extremity Edema and Hydrocele

et al. 2012

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Herein we report a 57-year-old man with lower extremity edema and swelling in the scrotum who was found to have a periaortic soft tissue mass and hydronephrosis by computed tomography. With the most plausible diagnosis of retroperitoneal fibrosis, corticosteroid therapy was initiated; however, it did not improve his symptoms. Upper gastroscopy performed on day 20 post admission showed ulcerative regions with an irregular border and fusion of thickened rugae at the gastric angle; the diagnosis of gastric adenocarcinoma was confirmed histologically. It is important to always be aware of unrecognized malignancies that are accompanied by retroperitoneal fibrosis.

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Section: Discussioncontrasting

confidence: 59%

Retroperitoneal Fibrosis in a Patient with Gastric Cancer Manifested by Lower Extremity Edema and Hydrocele

et al. 2012

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“…Fluorodeoxyglucose Positron Emission Technology (PET) is a non-invasive, safe, whole body imaging method with potential to identify other diseased sites, any associated autoimmune or neoplastic disorder and also can be used for surveillance of disease activity [19]. Biopsy can be done to identify histopathology of the disease [20].…”

Section: Discussionmentioning

confidence: 99%

Deep Vein Thrombosis /Pulmonary Embolism in a Patient with Retroperitoneal Fibrosis: A Case Report

Agrawal¹

2012

J Clin Case Rep

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Introduction: Retroperitoneal Fibrosis (RPF) is a clinicopathological condition characterized by inflammatory fibrotic reaction around infrarenal aorta, iliac vessels and surrounding retroperitoneum with myriad presentations. This case report shows how a Deep Vein Thrombosis (DVT) and subsequent Pulmonary Embolism (PE) can be a potential complication of this disease. A potential temporal association was seen with chronic beta blocker use and retroperitoneal fibrosis.

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“…It can be a helpful tool in making therapeutic decisions, e.g. about removing the ureteral stent or reducing the dose of immunosuppressant [48]. In a high proportion of patients, despite a good clinical response and a decrease of inflammatory parameters, the imaging tests show a remaining residual mass.…”

Section: Diagnosticsmentioning

confidence: 99%

Retroperitoneal fibrosis – the state-of-the-art

2016

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Retroperitoneal fibrosis (RPF) is a rare disease, hallmarked by inflammation and deposition of fibrous tissue around the abdominal aorta. This process may spread contiguously and involve adjacent structures, leading to many complications, among which the most frequent and most severe is ureteral obstruction. The condition usually has idiopathic origin (idiopathic retroperitoneal fibrosis – IRF), but can also develop secondarily to a number of factors. The etiology of the disease remains unclear. Current research suggests that about half of the cases of IRF may be a symptom of a recently discovered, clinically heterogeneous immunoglobulin G4-related disease (IgG4-RD). Corticosteroids are the first-line treatment for IRF, but effective attempts to use immunosuppressants are also made. This paper presents the current state of knowledge on the etiopathogenesis, clinical presentation, diagnosis and therapeutic possibilities in different forms of RPF. Based on the latest research, an analysis of the relationship between IRF and IgG4-RD was performed.

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Positron emission tomography as a tool for the 'tailored' management of retroperitoneal fibrosis: a nephro-urological experience

Abstract: PET is a promising tool for surveillance of disease activity and for planning the removal of ureteral stents in RF.

Cited by 25 publications

References 34 publications

Retroperitoneal Fibrosis in a Patient with Gastric Cancer Manifested by Lower Extremity Edema and Hydrocele

Retroperitoneal Fibrosis in a Patient with Gastric Cancer Manifested by Lower Extremity Edema and Hydrocele

Deep Vein Thrombosis /Pulmonary Embolism in a Patient with Retroperitoneal Fibrosis: A Case Report

Retroperitoneal fibrosis – the state-of-the-art

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