Post-exercise ankle–brachial index decline and risk of all-cause mortality: A meta-analysis

Sun, Hongxiao; Liu, Longguang; Jing, Yuntian; Wang, Jian; Zhou, Yao; Chen, Kang; Hu, Xinhua

doi:10.1177/2047487319849507

Cited by 2 publications

(2 citation statements)

References 14 publications

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“…There is a higher prevalence of lesions in the dorsalis pedis artery than in popliteal or anterior/posterior tibial arteries; the dorsalis pedis artery was the first artery to develop diabetic macrovascular disease and was crucial for early screening ( 29 ). It could be viewed as a representation of the systemic vasculature in T2DM.…”

Section: Discussionmentioning

confidence: 99%

“…This results in damage to the vascular endothelium, which stimulates the release of multiple vasoactive factors from endothelial cells, resulting in an imbalance of vasodilator/constrictor factors (e.g., an imbalance in the secretion of nitric oxide/endothelin), which contributes to the development of PAD (28). There is a higher prevalence of lesions in the dorsalis pedis artery than in popliteal or anterior/posterior tibial arteries; the dorsalis pedis artery was the first artery to develop diabetic macrovascular disease and was crucial for early screening (29). It could be viewed as a representation of the systemic vasculature in T2DM.…”

Section: Discussionmentioning

confidence: 99%

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Effects and safety of Ginkgo biloba on blood metabolism in type 2 diabetes mellitus: a systematic review and meta-analysis

Zou,

Fang,

Han

et al. 2024

Front. Endocrinol.

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BackgroundThere has existed controversy regarding the use of Ginkgo biloba (GKB) for blood metabolism among type 2 diabetes mellitus(T2DM) patients, and we tried to analyze the effects and safety of GKB on T2DM patients.MethodsWe conducted a literature search between January 2003 and December 2022 of seven online databases (PubMed, Scopus, Embase, Google Scholar, Web of Sciences, Cochrane Library, and China National Knowledge Infrastructure). A systematic literature review and meta-analysis were performed to compare the effects and safety of GKB among T2DM patients. Four groups of parameters were extracted and analyzed: hemorheology parameters, lipid profile, glycemic control markers, and adverse events.ResultsIn the end, 13 eligible articles with 11 indicators among 1573 patients were included. In the hemorheology parameters section, GKB showed significantly lower plasma viscosity (PV) (SMD=-0.91, 95%CI [-1.45, -0.36], P<0.01) and hematocrit (Hct) (SMD=-0.60, 95%CI [-0.97, -0.24], P<0.01) than the control group. GKB shoed higher velocity of the dorsalis pedis artery (VDPA) (SMD=0.51, 95%CI [0.26, 0.76], P<0.01) and ankle brachial index (ABI) (SMD=0.71, 95%CI [0.32, 1.10], P<0.01) than the control. In both the lipid profile and glycemic control markers sections, we did not find any difference between GKB and control groups, including total cholesterol (TC), triglyceride (TG), low-density lipoprotein (LDL), high-density lipoprotein (HDL), hemoglobin A1c (HbA1c), and fasting serum glucose (FSG). In addition, we saw no difference in adverse events (AE). The sensitivity analysis and funnel plot showed that the results in this research were robust and had no publication bias.ConclusionIn conclusion, GKB might safely reduce the risk of peripheral arterial or even systemic cardiovascular disease. However, GKB did not directly improve lipid and blood glucose levels in T2DM patients.Systematic review registrationhttps://inplasy.com/, identifier INPLASY202350096.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Effects and safety of Ginkgo biloba on blood metabolism in type 2 diabetes mellitus: a systematic review and meta-analysis

Zou,

Fang,

Han

et al. 2024

Front. Endocrinol.

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Ankle-Brachial Index: Diagnostic Tool of Peripheral Arterial Disease and Predictor of Cardiovascular Risk—An Update of Current Knowledge

Poredos,

Stanek,

Catalano

et al. 2024

Angiology

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The ankle-brachial index (ABI) was introduced as a screening method for the diagnosis of lower extremity peripheral arterial disease (PAD). Later findings recognized ABI as a prognostic marker of adverse cardiovascular events due to its relation to atherosclerosis in other vascular territories. This narrative review aims to appraise the validity, reliability, and utility of ABI in the detection of PAD and the determination of global atherosclerotic cardiovascular risk. While the ABI value can be influenced by different physiological characteristics including age, sex, body position, and techniques used for ABI determination, it has high specificity and reproducibility in the assessment of vascular patients. In conclusion, when used correctly, the ABI remains a reliable and invaluable indicator of lower-limb perfusion and a useful tool for predicting the risk of future cardiovascular events. However, its underutilization in clinical settings is noteworthy.

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Post-exercise ankle–brachial index decline and risk of all-cause mortality: A meta-analysis

Cited by 2 publications

References 14 publications

Effects and safety of Ginkgo biloba on blood metabolism in type 2 diabetes mellitus: a systematic review and meta-analysis

Effects and safety of Ginkgo biloba on blood metabolism in type 2 diabetes mellitus: a systematic review and meta-analysis

Ankle-Brachial Index: Diagnostic Tool of Peripheral Arterial Disease and Predictor of Cardiovascular Risk—An Update of Current Knowledge

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