Post-menopausal osteoporosis: do body composition, nutritional habits, and physical activity affect bone mineral density?

Akkuş, Özlem Özpak; Atalay, B.

doi:10.20960/nh.03214

Cited by 7 publications

(4 citation statements)

References 25 publications

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“…A cross-sectional research of 100 premenopausal women in Spain found a negative connection between coffee intake and BMD, as evaluated by quantitative ultrasonography. [30] Caffeine and caffeine metabolites may have a role in the development of osteoporosis, according to this body of data. Furthermore, caffeine and BMD were examined at multiple places in a Mendelian randomized trial from Sweden, but no causal relationship was found.…”

Section: Discussionmentioning

confidence: 99%

Association of urinary caffeine and caffeine metabolites with bone mineral density in children and adolescents

Luo

Liu

Zheng³

et al. 2022

Medicine

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In epidemiological research, the link between coffee consumption and bone mineral density (BMD) is still debated. Moreover, there hasn't been any research on the relationship between urine caffeine and caffeine metabolites and BMD. This study aimed to investigate if there was a connection between urine caffeine and its metabolites and BMD in people between the ages of 8 and 19. Using data from the National Health and Nutrition Examination Survey 2009 to 2014, multivariate logistic regression models were utilized to investigate the association between urinary caffeine and caffeine metabolites and total BMD. Fitted smoothing curves and generalized additive models were also used. A total of 1235 adolescents were included in this analysis, after controlling for various variables, we found that the association between urinary theophylline and total BMD was negative, whereas the association between urinary paraxanthine, theobromine and caffeine and total BMD was positive. In our study, an inverted U-shaped association between urinary paraxanthine and urinary caffeine was found with BMD in women. In this crosssectional study, the correlation between urinary caffeine and its metabolites and total BMD differed by sex and race. More studies are needed to confirm the results of this study and to investigate the underlying causes.

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Section: Discussionmentioning

confidence: 99%

Association of urinary caffeine and caffeine metabolites with bone mineral density in children and adolescents

Luo

Liu

Zheng³

et al. 2022

Medicine

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“…[ 23 , 24 ] Nonetheless, other studies refute this conclusion, with one cross-sectional study of 100 premenopausal women in Spain reporting that coffee consumption negatively affected BMD as measured by quantitative ultrasonography. [ 25 ] These findings suggest that caffeine and caffeine metabolites may play a role in the development of osteoporosis. In our study, we found a U-shaped relationship between urinary theophylline, urinary paraxanthine, and BMD, with inflection points at levels of 0.006 mmol/L for theophylline and 0.052 mmol/L for paraxanthine.…”

Section: Discussionmentioning

confidence: 99%

Association between urine caffeine metabolites and bone mineral density: A population-based study

Tan,

Shen,

Tang

et al. 2023

Medicine

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The association between coffee intake and bone mineral density (BMD) remains a subject of debate in epidemiological research. Furthermore, the potential relationship between BMD and urine caffeine or caffeine metabolites has not yet been explored. Therefore, the present study aimed to investigate the possible association between BMD and urine caffeine and its metabolites in U.S. adults. We employed multivariate linear and logistic regression models to analyze the relationship between urine caffeine and caffeine metabolites and lumbar BMD using data from the National Health and Nutrition Examination Survey (NHANES) from 2009 to 2014. Additionally, fitted smoothing curves and generalized additive models were used. After adjusting for several factors, we found no significant association between urine caffeine and its metabolites and BMD. However, subgroup analyses stratified by gender and ethnicity showed that the relationship between urine caffeine and its metabolites and lumbar BMD remained consistent. Our investigation revealed that the inflection points for the U-shaped relationship between urinary theophylline and paraxanthine and BMD were observed at levels of 0.006 mmol/L for theophylline and 0.052 mmol/L for paraxanthine. In this cross-sectional study, we found no significant correlation between urine caffeine and its metabolites and BMD. However, more research is required to confirm our findings, as well as to investigate the underlying mechanisms.

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“…Definition: Osteoporosis is defined by the World Health Organization as a condition affecting the bones on a systemic level, marked by reduced bone density, deterioration of bone structure, and a higher likelihood of suffering from fractures due to fragility, with hip fractures being the most severe outcome [1]. In osteoporosis can be divided into two main categories: primary and secondary osteoporosis.…”

Section: Osteoporosismentioning

confidence: 99%

Advances in the diagnosis and treatment of osteoporosis and sarcopenia

2024

medsc

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With the increase in human life expectancy and the advent of an aging society, the prevalence of osteoporosis and sarcopenia, as age-accelerating diseases, has been increasing year by year, creating a heavy burden on society. Osteoporosis and sarcopenia have multiple etiologies, including genetic, metabolic, lifestyle, and exercise variables. Moreover, poor nutritional status, including insufficient consumption of calcium, vitamin D, and protein, as well as decreased physical activity, are major risk factors for sarcopenia and osteoporosis. Osteoporosis and sarcopenia raise chances of fractures and falls, affects exercise capacity, reduces quality of life, and directly or indirectly affects the life expectancy of the population. Adequate nutritional supplementation and physical activity are the main strategies for preventing and delaying osteoporosis and sarcopenia, in addition to pharmacological interventions that are thought to be potentially beneficial. This review provides the progress of epidemiologic, diagnostic, and therapeutic studies of osteoporosis and sarcopenia, and provides some reference value for further research.

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Post-menopausal osteoporosis: do body composition, nutritional habits, and physical activity affect bone mineral density?

Abstract: Post-menopausal osteoporosis: do body composition, nutritional habits, and physical activity affect bone mineral density? Osteoporosis posmenopáusica: ¿afectan a la densidad mineral ósea la composición corporal, los hábitos nutricionales y la actividad física?

Cited by 7 publications

References 25 publications

Association of urinary caffeine and caffeine metabolites with bone mineral density in children and adolescents

Association of urinary caffeine and caffeine metabolites with bone mineral density in children and adolescents

Association between urine caffeine metabolites and bone mineral density: A population-based study

Advances in the diagnosis and treatment of osteoporosis and sarcopenia

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