Post Percutaneous Coronary Intervention Pericarditis and Positive Effect of Colchicine on Patient Condition

Abstract

The global prevalence of MI in individuals < 60 years was found to be 3.8%. Also, following the assessment of 20 eligible investigations with a sample size of 5,071,185 individuals (> 60 years), this value was detected at 9.5% [1]. Cardiac catheterization is an invasive procedure used for both diagnostic as well as therapeutic purpose in patients having myocardial infarction either STEMI OR NSTEMI. It is important to understand that, the chances of having any major complication post coronary angiography occur in less than 2% of the population, with mortality of less than 0.08% [2]. Rupture of large vessels during visualization and stenting needs to be consider, although it is highly unlikely. As a result of any perforation of large vessel leads to pericardial effusion and inflammation of pericardium. Our case study is about a 43-year-old male, who was diagnosed with pericarditis. His presenting symptoms and ECG changes were mimicking inferior wall non-ST elevation myocardial infarction (NSTEMI) or old infarction changes along with small Q wave, there were no typical findings on ECG indicative of pericarditis. Laboratory findings showed raised cardiac markers (troponin 1, CKMB).Patient underwent for coronary angiography and no acute pathology was seen. Follow up echocardiography revealed mild pericardial fluid accumulation that triggered his recurrent chest pain. On the bases of his recurrent symptoms, a course of anti-inflammatory drug that is colchicine 0.5mg was initiated, which is highly recommended to prevent recurrent pericarditis. Chest pain was relieved and ST segment depression almost returned to normal base line after 3 weeks though it was old infarction it takes usually 4 to 6 weeks return to normal. Despite the lack of specific clinical manifestation, post-traumatic pericarditis should be considered in patients with symptoms and signs of pericarditis and a prior history of iatrogenic injury or thoracic trauma.