Post-stroke depression: Prevalence and relationship with disability in chronic stroke survivors

Srivastava, Abhishek; Taly, Arun B.; Gupta, Anupam; Murali, T

doi:10.4103/0972-2327.64643

Cited by 95 publications

(69 citation statements)

References 23 publications

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“…In this present study urban dwellers had higher proportions of PSD compared to rural dwellers; this is similar to earlier work 36 . This could be due to locations where the two centers where this study was conducted are urban and serve mainly urban dwellers, although one of them is a national referral serving the whole country.…”

Section: Discussionsupporting

confidence: 93%

Post-stroke depression among stroke survivors attending two hospitals in Kampala Uganda

Gyagenda¹,

Ddumba²,

Odokonyero³

et al. 2016

Afr H. Sci.

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Background: The burden of stroke worldwide is increasing rapidly. There is paucity of data on post-stroke depression (PSD) among stroke survivors in Uganda, despite the high prevalence of PSD reported elsewhere. Methods: In a cross-sectional study, we assessed adult participants with confirmed first stroke with a standardized questionnaire. The Patient Health Questionnaire-9 was used to assess for depression among non-aphasic patients while the Aphasic Depression Rating Scale was administered to aphasic patients. Univariable and multivariable analyses performed to describe associations with PSD. Results: Forty three females (58.9%) and 30 males (41.1%) who had a stroke participated. Fifty eight (79.5%) had ischemic strokes and 12 participants (16.4%) were aphasic. The prevalence of PSD among the study participants was 31.5%. PSD was higher among patients assessed within 6 months after the onset of stroke. PSD was strongly associated with the total Barthel index of activities of daily living (BIADL) score; p=0.001. There was no significant association between demographic characteristics and PSD. Conclusion: There is a high prevalence of unrecognized post-stroke depression. Post-stroke depression was strongly associated with the patient's inability to undertake activities of daily life. There is urgent need for integration of screening for and management of post-stroke depression among stroke survivors.

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Section: Discussionsupporting

confidence: 93%

Post-stroke depression among stroke survivors attending two hospitals in Kampala Uganda

Gyagenda¹,

Ddumba²,

Odokonyero³

et al. 2016

Afr H. Sci.

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“…PSD is a significant health concern being associated with increased disability [8,9], mortality [10], poorer functional outcomes [11], reduced quality of life (QoL) [12,13] and increased use of healthcare services [14]. Previous perceptions from earlier observational studies indicate that the greatest risk for PSD occurs within a few months of stroke onset [5,15,16], although a recent systematic review found the risk was similar (around 30%) in the early, medium and long-term recovery stages [17].…”

Section: Introductionmentioning

confidence: 99%

Predictors of depression and anxiety in community dwelling stroke survivors: a cohort study

White

Attia

Sturm

et al. 2014

Disability and Rehabilitation

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While more common than depression immediately post-stroke, anxiety attenuates while the burden of depression persists over 12 months. Clinical programs should assess anxiety and depression, provide treatment pathways for those identified, and address modifiable risk factors, especially social support and social engagement. Implications for Rehabilitation Psychological distress post stroke is persisting. Multi-disciplinary teams that establish goals with patients promoting social and community engagement could assist in managing psychological morbidity. A shift towards promoting longer-term monitoring and management of stroke survivors must be undertaken, and should consider the factors that support and hinder psychological morbidity.

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“…The social, physical and psychological consequences of stroke are devastating [7–10]. These consequences are described by studies that elaborate Quality of Life(QOL).…”

Section: Introductionmentioning

confidence: 99%

Quality of life after stroke in Pakistan

et al. 2016

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BackgroundThere is very little information about the quality of life (QOL) of stroke survivors in LMIC countries with underdeveloped non communicable health infrastructures, who bear two thirds of the global stroke burden.MethodologyWe used a sequential mix methods approach. First, a quantitative analytical cross-sectional study was conducted on 700 participants, who constituted 350 stroke survivor and their caregiver dyads. QOL of stroke survivor was assessed via Stroke Specific Quality of Life Scale (SSQOLS) whereas QOL of caregivers was assessed through RAND-36. In addition; we assessed complications, psychosocial and functional disability of stroke survivors. Following this quantitative survey, caregivers were qualitatively interviewed to uncover contextually relevant themes that would evade quantitative surveys. Multiple linear regression technique was applied to report adjusted β-coefficients with 95% C.I.ResultsThe QOL study was conducted from January 2014 till June 2014, in two large private and public centers. At each center, 175 dyads were interviewed to ensure representativeness. Median age of stroke survivors was 59(17) years, 68% were male, 60% reported depression and 70% suffered post-stroke complications. The mean SSQOLS score was 164.18 ± 32.30. In the final model severe functional disability [adjβ -33.77(-52.44, -15.22)], depression [adjβ-23.74(-30.61,-16.82)], hospital admissions [adjβ-5.51(-9.23,-1.92)] and severe neurologic pain [adjβ -12.41(-20.10,-4.77)] negatively impacted QOL of stroke survivors (P < 0.01).For caregivers, mean age was 39.18 ± 13.44 years, 51% were female and 34% reported high stress levels. Complementary qualitative study revealed that primary caregivers were depressed, frustrated, isolated and also disappointed by health services.ConclusionThe QOL of Stroke survivors as reported by SSQOLS score was better than compared to those reported from other LMIC settings. However, Qualitative triangulation revealed that younger caregivers felt isolated, depressed, overwhelmed and were providing care at great personal cost. There is a need to develop cost effective holistic home support interventions to improve lives of the survivor dyad as a unit.Trial registration NCT02351778 (Registered as Observational Study).Electronic supplementary materialThe online version of this article (doi:10.1186/s12883-016-0774-1) contains supplementary material, which is available to authorized users.

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Post-stroke depression: Prevalence and relationship with disability in chronic stroke survivors

Cited by 95 publications

References 23 publications

Post-stroke depression among stroke survivors attending two hospitals in Kampala Uganda

Post-stroke depression among stroke survivors attending two hospitals in Kampala Uganda

Predictors of depression and anxiety in community dwelling stroke survivors: a cohort study

Quality of life after stroke in Pakistan

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