Post-traumatic and postoperative endophthalmitis: a comparison of visual outcomes.

Abstract

Endophthalmitis complicating penetrating ocular injury generally has a worse visual prognosis than does postsurgical endophthalmitis.' 2 Several factors may account for the differences in final visual acuities between these groups, such as the virulence of the infecting organisms, the severity of any associated ocular trauma, and the rapidity of diagnosis and institution of appropriate therapy. ' The use of intravitreal antibiotics and vitrectomy has improved success rates in the treatment of experimental and clinical endophthalmitis in selected cases.' To understand better the factors affecting the prognosis of traumatic versus postoperative endophthalmitis we retrospectively reviewed 50 consecutive cases of exogenous endophthalmitis. Subjects and methodsThis study included 50 consecutive cases of exogenous endophthalmitis that had presented to the

Experimental Staphylococcal Endophthalmitis

“…Seventy-one percent of 323 isolates were identified as coagulase-negative cocci and 9.9% as S. aureus . Other studies [5, 70, 71, 72, 73]have also shown that coagulase-negative staphylococci (e.g., S. epidermidis ) were the most frequent isolates followed by S. aureus . It is believed that one of the sources of these bacteria is the patient’s normal flora of the conjunctiva, lids, and lashes [74, 75, 76, 77].…”

Effect of taurolidine on the normal eyelid and conjunctival flora

“…[22][23][24][25][26] The vehicle used in this study contained the same concentration of polyvinylpyrrolidone, and we observed an insignificant decrease in the number of colonies after the therapy with the vehicle or saline. The vehicle or saline may possibly wash bacteria from the conjunctival cul-de-sac in conjunction with tears as an irrigation liquid as has been demonstrated that saline irrigation leading to a decrease in bacterial counts via a washout phenomenon.…”

<i>Listeria monocytogenes</i> Endophthalmitis in a Renal-Transplant Patient Receiving Ciclosporin

“…If the infectious process reaches the vitreous cavity, an emergency vitrectomy will allow drainage of the vitreous abscess, elimination of the de structive elements, good diffusion of the anti biotics and clearing of the ocular media. Such treatment improves the visual prognosis in en dophthalmitis [16],…”

“…Exogenous contamination is ob served either after a perforating trauma or af ter intraocular surgery. The microorganisms most frequently encountered are staphylococci and gram-negative bacilli [16]. Endophthalm itis of endogenous origin is secondary to bac teremia.…”