Poster #241 OBSESSIVE COMPULSIVE SYMPTOMS BUT NOT OBSESSIVE-COMPULSIVE DISORDER ARE RELATED TO LOWER QUALITY OF LIFE IN SCHIZOPHRENIA

Üçok, Alp; Tihan, Aysu; Tükel, Raşit

doi:10.1016/s0920-9964(12)71073-3

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“…These findings were not influenced by chronicity of illness in the participants, as well as the concurrent use of Clozapine. Furthermore, the presence of OCS had been associated with higher suicidality in patients with schizophrenia 12,54 in which our study also revealed similar finding. This is clinically important as practicing clinicians ought to be aware of the impact of OCS, hence be more vigilant when assessing this group of patients for suicidality.…”

Section: Discussionsupporting

confidence: 87%

The effect of obsessive compulsive symptoms on psychopathology in patients with schizophrenia

Seng¹,

Yee²,

Danaee³

et al. 2018

Arch. Clin. Psychiatry (São Paulo)

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Background: There is a growing interest on the impact of comorbid obsessive-compulsive symptoms (OCS) on the course and severity of schizophrenia in recent years. Objectives: This study determined the prevalence of OCS in schizophrenia patients and the clinical outcomes of the comorbidity. Methods: A total of 220 schizophrenia patients were recruited. All the participants completed Structure Clinical Interview version, Yale Brown Obsessive Compulsive Scale, Calgary Depression Scale for Schizophrenia, Columbia Suicide Severity Rating Scale and World Health Organization Quality of Life-Brief Version (WHOQOL-BREF). Results: Significantly higher number of schizophrenia patients with OCS were taking Clozapine (p = 0.023) and antidepressants (p = 0.013). Schizophrenia patients with OCS showed more severe positive (p < 0.001) and general symptoms (p < 0.001) of schizophrenia, higher depressive symptoms (p = 0.013), higher suicidality (p < 0.001), more hospitalization (p = 0.044), poorer physical (p = 0.034) and psychological (p = 0.032) domain in WHOQOL-BREF. Discussion: Schizophrenia patients with OCS are associated with more severe psychopathology and depressive symptoms which subsequently suffered poorer physical and psychological health. Hence, recognition of OCS in schizophrenia and early initiation of effective treatment may be able to reduce the burden for people with chronic mental illness.

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Section: Discussionsupporting

confidence: 87%