Posterior Segment Ocular Manifestations in Patients with HLA-B27—associated Uveitis

Rodriguez, Alejandro; Akova, Yonca A.; Pedroza-Seres, Miguel; Foster, C. Stephen

doi:10.1016/s0161-6420(94)31179-1

Cited by 112 publications

(75 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This type of uveitis usually has a good therapeutic response to corticosteroid therapy. 2,3 We now report a case of HLA-B27-associated …”

mentioning

confidence: 87%

“…5 Posterior segment involvement in HLA-B27-associated uveitis occurs somewhere between 4 and 17.4% in Caucasians. 2,6 Benitez del Castillo reported that the blood-aqueous barrier had been broken when HLA-B27-positive acute anterior uveitis was in active stage. 7 However, these cases usually have good responses to corticosteroid or immunosuppressive therapy.…”

Section: Commentmentioning

confidence: 99%

See 1 more Smart Citation

Proliferative vitreoretinopathy developed in HLA-B27-associated uveitis

Kodama

Numaga

Kaburaki

et al. 2003

Eye

View full text Add to dashboard Cite

“…This type of uveitis usually has a good therapeutic response to corticosteroid therapy. 2,3 We now report a case of HLA-B27-associated …”

mentioning

confidence: 87%

Section: Commentmentioning

confidence: 99%

Proliferative vitreoretinopathy developed in HLA-B27-associated uveitis

Kodama

Numaga

Kaburaki

et al. 2003

Eye

View full text Add to dashboard Cite

“…This is similar to reports of complications of uveitis associated with SpA in existing literature. 12,15,16 …”

Section: Characteristics Of Uveitismentioning

confidence: 99%

Uveitis of spondyloarthritis in Indian subcontinent: a cross sectional study

et al. 2017

View full text Add to dashboard Cite

Background: The seronegative spondyloarthritis (SpA) are known to have intimate association with ocular inflammatory disease. While anterior uveitis accounts for 50-92% of all cases of uveitis in the West, it ranges between 28 and 50% in the Asian countries. The aim of this study was to document the clinical profile of uveitis in patients with spondyloarthritis in the Indian subcontinent.Methods: In our hospital based cross sectional study, 166 patients fulfilling Assessment of SpondyloArthritis international Society’ (ASAS) criteria for spondyloarthritis (SpA) were evaluated for evidence and nature of uveitis, including by a slit lamp bio microscope. The characteristics of Uveitis were defined as per the SUN (Standardization of Uveitis Nomenclature) Working Group criteria. 84.3% (140) of the patients were male.Results: Ankylosing spondylitis was the commonest type of spondyloarthritis accounting for 69.3% patients. Evidence of past or present uveitis was found in 16.3% patients. Of the patients with uveitis 96.3% had anterior uveitis. 88.9% of the patients had redness of the eye, and 85.2% reported pain in the eye during an episode of uveitis. Mean duration of musculoskeletal symptoms prior to the diagnosis of SpA was 4.36 years. Of the 24 patients who could recall the course of uveitis 70.8% (17) had recurrent episodes. As a complication of uveitis 18.5% had cataract, and 14.8% had posterior synechiae. 78.3% patients were HLA-B27 positive. 19.2% of HLA-B27 positive patients had uveitis, whereas only 5.6% out of the 36 HLA-B27 negative patients had uveitis.Conclusions: The proportion of patients with uveitis in our study (16.3%) was considerably less than in other studies. The characteristics and profile of uveitis in our cohort of SpA patients from the Indian subcontinent were similar to those previously reported in literature.

show abstract

“…Complications included extensive, persistent synechiae, glaucoma secondary to the inflammation itself or to the use of topical steroids, vitritis, papillitis, and cystoid macular edema [7][8][9].…”

Section: Uveitis and Hla-b27mentioning

confidence: 99%

Uveitis, diabetes, or cataracts? The mysterious case of the blurry left eye

Goldberg¹

2017

Eye Care Vis

View full text Add to dashboard Cite

Uveitis and diabetes can lead to macular edema and cataracts, resulting in reduced vision. This report discusses a unique case history of a patient presenting with all of these ocular pathologies, in which we were challenged to determine the cause of ocular inflammation and take a stepwise approach to managing each condition. Through utilization of clinical reasoning and ancillary testing, we were able to identify cataracts as the primary cause of reduced vision. The patient's chief complaint was successfully resolved with a treatment regimen of high-dosage topical steroid and cycloplegic agent.

show abstract

Posterior Segment Ocular Manifestations in Patients with HLA-B27—associated Uveitis

Cited by 112 publications

References 25 publications

Proliferative vitreoretinopathy developed in HLA-B27-associated uveitis

Proliferative vitreoretinopathy developed in HLA-B27-associated uveitis

Uveitis of spondyloarthritis in Indian subcontinent: a cross sectional study

Uveitis, diabetes, or cataracts? The mysterious case of the blurry left eye

Contact Info

Product

Resources

About