Postoperative pain control with intrathecal morphine

Abstract

Summary A clinicalstudy of the use of intrathecal morphine in two groups

Pharmacokinetic aspects of spinal morphine analgesia

“…The intrathecal approach has been used for the control of pain after orthopaedic, abdominal and open-heart surgery, and for the control of pain in labour and myocardial infarction (GJESSING & TOMLIN 1981, PAS-QUALUCCI et a1 1981, BARAKA et a1 1981, BENGTS-SON et al 1983, KALSO 1983, TAKASAKI & ASANO 1983, JONES et a1 1984, PATERSON et a1 1984.…”

Delayed respiratory depression associated with 0.15 mg intrathecal morphine for cesarean section: a review of 1915 cases

“…In nonobstetric patients, a number of case reports describe respiratory depression caused by various doses of intrathecal morphine for postoperative analgesia [1,[7][8][9]. There have been four relatively large-scale (number of subjects ≥ 100) studies [10][11][12][13].…”

Intrathecal morphine combined with hyperbaric tetracaine

“…the respiratory depression ha5 also been reported with the use of larger doses OF morphine (0.5-2.0 mg).i- 4 We would like to report on the efficacy ofintrathecal morphine given at the same t i n e as spinal analgesia for postoperative pain relief, ar.d to define the dose needed to produce analgesia without causing respiratory depression.…”