Postpartal Heart Failure

Hull, Edgar; Hidden, Eleanor

doi:10.1097/00007611-193803000-00010

Cited by 59 publications

(22 citation statements)

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“…The present study, an extension of a similar study reported by Hull in 1937. relates this type of case to the terminal aspects of pregnancy and the puerperium with an incidence of 1 in 1300 deliveries. Four case reports with necropsy findings, together with the clinical observations made on a total of 15 cases are presented.…”

supporting

confidence: 66%

Idiopathic Myocardial Failure in the Last Trimester of Pregnancy and the Puerperium

Meadows

1957

Circulation

110

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Instances of congestive heart failure due to unexplained myocardial disease are not infrequently discussed in the literature. The present study, an extension of a similar study reported by Hull in 1937. relates this type of case to the terminal aspects of pregnancy and the puerperium with an incidence of 1 in 1300 deliveries. Four case reports with necropsy findings, together with the clinical observations made on a total of 15 cases are presented. The frequency of recurrence of the syndrome with subsequent pregnancies and the predominance in the puerperium of this type of congestive failure over those of the usual etiologies suggests that the relationship to pregnancy is not fortuitous.

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supporting

confidence: 66%

Idiopathic Myocardial Failure in the Last Trimester of Pregnancy and the Puerperium

Meadows

1957

Circulation

110

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“…46 Subsequent reports from the United States, South Africa, Jamaica, Latin America, and West Africa have revealed that the condition is common in developing countries, particularly among women of African descent, and is uncommon in industrialized countries. [47][48][49][50][51] Furthermore, in developed countries, PCM often has a more malignant course, with histological evidence of myocarditis, which may demand treatment with immunosuppressive drugs and, in some cases in which drugs fail, cardiac transplantation.…”

Section: Peripartum Cardiomyopathymentioning

confidence: 99%

Epidemiology and Etiology of Cardiomyopathy in Africa

Sliwa

Damasceno²,

Mayosi³

2005

Circulation

226

144

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Background— Cardiomyopathy, an often irreversible form of heart muscle disease that is associated with a dismal outcome, is endemic in Africa. The primary objective of this review was to summarize the current state of knowledge on the epidemiology and etiology of cardiomyopathy in people living in Africa and to identify new avenues for research. Methods and Results— We searched MEDLINE (January 1, 1966, through February 12, 2005) and reference lists of articles for relevant references. Unlike other parts of the world in which cardiomyopathy is rare, dilated cardiomyopathy is a major cause of heart failure throughout Africa. Similarly, peripartum cardiomyopathy is ubiquitous on the continent, with an incidence ranging from 1 in 100 to 1 in 1000 deliveries. There is an apparent marked regional variation in the pathogenesis of dilated cardiomyopathy and peripartum cardiomyopathy, underlining the heterogeneity of causative factors in these conditions. By contrast, endomyocardial fibrosis is restricted to the tropical regions of East, Central, and West Africa. Although the pathogenesis of endomyocardial fibrosis is not fully understood, it seems that the conditioning factors are geography and diet, the triggering factor may be an as yet unidentified infective agent, and the perpetuating factor is eosinophilia. Although epidemiological studies are lacking, hypertrophic cardiomyopathy and arrhythmogenic right ventricular cardiomyopathy seem to have characteristics similar to those of other populations elsewhere in the world. Conclusions— There is a need for large-scale epidemiological studies of the incidence, prevalence, determinants, and outcome of cardiomyopathy in Africa to inform strategies for the treatment and prevention of heart muscle disease on the continent.

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“…1,2 The first large case series was published in New Orleans in 1937, 3,4 but the syndrome remained poorly defined until the seminal publications by Demakis and Rahimtoola 5 and Demakis et al 6 in 1971. Those authors published data on 27 patients, specifically defined the syndrome as occurring in the peripartum period, and first introduced the term peripartum cardiomyopathy (PPCM).…”

mentioning

confidence: 99%

Peripartum Cardiomyopathy

2016

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Abstract-Peripartum cardiomyopathy is a potentially life-threatening pregnancy-associated disease that typically arises in the peripartum period and is marked by left ventricular dysfunction and heart failure. The disease is relatively uncommon, but its incidence is rising. Women often recover cardiac function, but long-lasting morbidity and mortality are not infrequent. Management of peripartum cardiomyopathy is largely limited to the same neurohormonal antagonists used in other forms of cardiomyopathy, and no proven disease-specific therapies exist yet. Research in the past decade has suggested that peripartum cardiomyopathy is caused by vascular dysfunction, triggered by late-gestational maternal hormones. Most recently, information has also indicated that many cases of peripartum cardiomyopathy have genetic underpinnings. We review here the known epidemiology, clinical presentation, and management of peripartum cardiomyopathy, as well as the current knowledge of the pathophysiology of the disease.

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Postpartal Heart Failure

Cited by 59 publications

References 0 publications

Idiopathic Myocardial Failure in the Last Trimester of Pregnancy and the Puerperium

Idiopathic Myocardial Failure in the Last Trimester of Pregnancy and the Puerperium

Epidemiology and Etiology of Cardiomyopathy in Africa

Peripartum Cardiomyopathy

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